Anisotropic Tuning of Graphite Thermal Conductivity by Lithium Intercalation by Xin Qian (714942)

“…We found that intercalation of lithium has an anisotropic effect on tuning the thermal conductivity: the thermal conductivity in the basal plane decreases monotonically from 1232 W/m·K of pristine graphite to 444 W/m·K of the fully lithiated LiC₆, while the thermal conductivity along the <i>c</i>-axis decreases first from 6.5 W/m·K for graphite to 1.3 W/m·K for LiC₁₈ and then increases to 5.0 W/m·K for LiC₆ as the lithium composition increases. …”

Dung Beetles along a Tropical Altitudinal Gradient: Environmental Filtering on Taxonomic and Functional Diversity by Cássio Alencar Nunes (2852327)

“…The altitudinal gradient ranged from 800 up to 1400 m a.s.l. and we collected dung beetles at every 100 m of altitude. …”

Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma by Bo Li (112195)

“…Herein, we report the structure-guided development of a series of covalent inhibitors of FAK. These new compounds displayed highly potent inhibitory potency against FAK enzymatic activity with IC₅₀ values in the nanomolar range. …”

The productivity of a research unit as a function of the funding <i>x</i>. by Miguel Navascués (164739)

Presentation1_The impact of Climate Change on extreme winds over northern Europe according to CMIP6.pdf by Xiaoli Guo Larsén (12502987)

“…We obtain the possible effect of climate change through the comparison of the extreme wind parameters, including the 50-year wind and the 95%-percentile of the wind speed, and the change in turbine class at 50 m, 100 m and 200 m, between a near future period (2020–2049) and the historic period (1980–2009). …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Validation of NUMB as a target for <i>miR-146a</i>. by Pei-Shi Hung (489732)

Image_1_Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.TIFF by Wenfei Xia (5055482)

Anti-inflammatory Meroterpenoids from <i>Baeckea frutescens</i> by Ji-Qin Hou (3642946)

“…Compound <b>8</b> exhibited anti-inflammatory activity with an IC₅₀ value of 0.36 μM, which might be related to the regulation of the NF-κB signaling pathway via the suppression of p65 nuclear translocation and the consequent decrease of IL-6 and TNF-α.…”

Anti-inflammatory Meroterpenoids from <i>Baeckea frutescens</i> by Ji-Qin Hou (3642946)

“…Compound <b>8</b> exhibited anti-inflammatory activity with an IC₅₀ value of 0.36 μM, which might be related to the regulation of the NF-κB signaling pathway via the suppression of p65 nuclear translocation and the consequent decrease of IL-6 and TNF-α.…”

Anti-inflammatory Meroterpenoids from <i>Baeckea frutescens</i> by Ji-Qin Hou (3642946)

“…Compound <b>8</b> exhibited anti-inflammatory activity with an IC₅₀ value of 0.36 μM, which might be related to the regulation of the NF-κB signaling pathway via the suppression of p65 nuclear translocation and the consequent decrease of IL-6 and TNF-α.…”

High blood glucose levels in rats after exposure to STZ. by Shatw Khalid Ali (13020885)

Potent 5‑Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1–UBE2M Interaction by Wenjuan Zhou (115285)

“…After finding a novel inhibitor <b>DC-1</b> with IC₅₀ = 1.2 μM, we performed a series of chemical optimizations, which finally led to the discovery of a potent thiazole containing 5-cyano-6-phenylpyrimidin-based inhibitor <b>DC-2</b> (IC₅₀ = 15 nM). …”

Reducing inherent biases introduced during DNA viral metagenome analyses of municipal wastewater by Nichole E. Brinkman (5052314)

“…<div><p>Metagenomics is a powerful tool for characterizing viral composition within environmental samples, but sample and molecular processing steps can bias the estimation of viral community structure. …”

The effects of metformin, donepezil, insulin glargine, and glibenclamide on brain biomarkers: Amyloid β 42, nitric oxide, acetylcholinesterase, malondialdehyde, β secretase, and pM... by Shatw Khalid Ali (13020885)

APL activity during tolerance acquisition promotes rapid tolerance. by Caleb Larnerd (20664157)

Enantiomeric Deoxycholic Acid:  Total Synthesis, Characterization, and Preliminary Toxicity toward Colon Cancer Cell Lines by Bryson W. Katona (2465581)

“…Using a modified method of the synthesis of <i>ent</i>-testosterone that proceeds through the (<i>R</i>)-(−)-Hajos−Parrish ketone, we have completed the successful synthesis of <i>ent</i>-DCA in 25 steps with a yield of 0.3% with all stereochemical assignments of the product confirmed by X-ray crystallography. …”

Enantiomeric Deoxycholic Acid:  Total Synthesis, Characterization, and Preliminary Toxicity toward Colon Cancer Cell Lines by Bryson W. Katona (2465581)

“…Using a modified method of the synthesis of <i>ent</i>-testosterone that proceeds through the (<i>R</i>)-(−)-Hajos−Parrish ketone, we have completed the successful synthesis of <i>ent</i>-DCA in 25 steps with a yield of 0.3% with all stereochemical assignments of the product confirmed by X-ray crystallography. …”

Enantiomeric Deoxycholic Acid:  Total Synthesis, Characterization, and Preliminary Toxicity toward Colon Cancer Cell Lines by Bryson W. Katona (2465581)

“…Using a modified method of the synthesis of <i>ent</i>-testosterone that proceeds through the (<i>R</i>)-(−)-Hajos−Parrish ketone, we have completed the successful synthesis of <i>ent</i>-DCA in 25 steps with a yield of 0.3% with all stereochemical assignments of the product confirmed by X-ray crystallography. …”