Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Decreased dendritic spine density in the mature cortex of <i>Cln6^nclf</i> mice. by Jeremy P. Morgan (479017)

The TLR4 activator LPS decreases photoreceptor viability and reducesWnt-mediated protection from oxidative stress. by Hyun Yi (57741)

“…White bars, no H₂O₂; black bars, with H₂O₂. Mean ± SD, *p<0.05 no additions with H₂O₂ (n = 5) compared with Wnt3a (n = 4); #p<0.05 50 µg/ml LPS+Wnt3a (n = 5) compared with Wnt3a+ H₂O₂ (n = 4). …”

Translocation of EHEC-Hly to mitochondria results in cytosolic cytochrome c release and ΔΨ_m decrease. by Martina Bielaszewska (79970)

“…(<b>C, D</b>) Intensities of the cytochrome c signals in mitochondrial (mito) and cytosolic (cyto) fractions shown in panels A and B were quantified in HBMEC (<b>C</b>) and Caco-2 cells (<b>D</b>) using densitometry, expressed in arbitrary densitometric units (DU) and are presented as means ± standard deviations from three independent experiments. * Significantly decreased (<i>p</i><0.05) compared to mitochondrial cytochrome c in control cells; ** significantly increased (<i>p</i><0.05) compared to cytosolic cytochrome c in control cells (unpaired Student's <i>t</i> test). …”

Claudin-18 knockdown by siRNA. (A) Claudin-18 siRNA significantly decreases the mRNA level of claudin-18 in MKN74. by Tadayuki Oshima (461127)

Sound stress exposure prolonged the period of decreased withdrawal threshold after complete Freund’s adjuvant (CFA) injection. by Satoka Kasai (3861115)

“…They showed a significant decrease in 50% withdrawal threshold on day 7 after CFA injection, and CFA-treated mice exposed to sound stress showed a significant decrease in 50% withdrawal threshold during days 7–21 after CFA injection (CFA, on day 7, ****<i>P</i> < 0.001 vs day 0, on day 10, ***<i>P</i> < 0.001 vs day0; CFA + stress, day 7, 10, 14, and 21, ****<i>P</i> < 0.0001 vs day 0, Dunnett’s test). …”

Pharmacologic inhibition of CaMKII and VEGF decreases tumorigenicity of 143B OS cells <i>in vitro</i>. by Paul G. Daft (720351)

Pairwise correlations in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Rac1 activity decreases in the presence of DECMA-1 and E-cadherin:Fc in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…<p>3-D MDCK cell aggregates were incubated with 10 µg/ml of DECMA-1 monovalent Fab' fragments (A), or 10 µg/ml of purified E-cadherin:Fc extracellular domain (E), or 10 µg/ml of Fc protein (I) for the indicated times. …”

The NADPH oxidase-related pathway contribute to decreased tube formation in EPCs under high concentrated oxLDL. by Feng-Yen Lin (143413)

Imatinib or masitinib decreases cell surface expression of mature c-Kit in UT-7/Epo cell line. by Diane D'allard (405441)

Cofilin concentration selectively decreases in spines following nLTD and involves the capthepsin B/L class of proteases. by Barbara Calabrese (553229)

PSD-95 decreases acid-evoked currents in hippocampal neurons, and is dependent upon <i>ASIC2</i>. by Anne Marie S. Harding (546425)

AP-3 knockdown resulted in decreased β-hexosaminidase release in FcεRI stimulated mast cells. by Elaine Zayas Marcelino da Silva (386342)

Electrical stimulation induces increased glucose uptake and decreased glycogen content in C2C12 myotubes. by Yasuko Manabe (107491)

Phytoplankton community mean cell size decreases with temperature and increases with dilution rate. by Kalista Higini Peter (296566)

Decreased lung tissue neutrophil infiltration in fCB-CD34⁺ cell-treated mice. by Xiaojia Huang (298132)

Bcl-xL protein levels were decreased in response to siRNA transfection in A549, SK-LU1 and NP-69 cells. by Norahayu Othman (495150)

“…<p>(<b>A</b>) Western blot indicating a significant decrease in Bcl-xL protein levels in comparison to non-transfected cells 48 h post-transfection. …”

Factors associated with abnormal left ventricular ejection fraction (decreased or increased) in patients with sepsis in the intensive care unit by Dong Geum Shin (6019568)

“…<div><p>Background</p><p>Sepsis-induced cardiomyopathy (SIC) is known to show cardiac dysfunction in patients with sepsis. Both a decrease or an increase in ejection fraction (EF), an indicator of cardiac function, can occur. …”

Presence of <i>Klf4</i> promoter elements decreases the effects of enhancer E2 in reporter assays. by Jack B. Waite (19762178)