Zn²⁺ is required for the enhancement of NMDAR fEPSPS which requires NR2B-containing NMDARs and activation of Src family kinases (SFK). by John A. Sullivan (6018725)

“…Statistical data are presented as mean ± SEM.</p>…”

Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey by John Ly (2901986)

“…</p><p>Conclusions</p><p>We detected a 30% decreased odds of FBD after the start of EVD in a rural Liberian county with relatively few cases. …”

Combination therapy of high dose PC1, kansui, and JQ1 reactivates latent HIV in a primary CD4+ T cell model of HIV latency. by Daniele C. Cary (3559394)

“…At 12 days post infection, cells were stimulated for 24 hours with: (A) PC1 (24 μM) and kansui (50 μg/ml) (B) PC1 (24 μM) and JQ1 (0.1 μM) (C) e PC1 (24 μM), kansui (50 μg/ml), and JQ1 (0.1 μM). …”

Combination therapy of low dose PC1, kansui, and JQ1 reactivates latent HIV in a primary CD4+ T cell model of HIV latency. by Daniele C. Cary (3559394)

“…At 12 days post infection, cells were stimulated for 24 hours with: (A) single and double PC1 (6 μM) and kansui (50 μg/ml) (B) single and double PC1 (6 μM) and JQ1 (0.1 μM) (C) single and triple PC1 (6 μM), kansui (50 μg/ml), and JQ1 (0.1 μM). …”

(A) Representative mEPSC traces from WT and hippocampal neurons in the presence of 10 μM bicuculline (Bic) and 1 μM tetrodotoxin (TTX) by Xiao-Wei Chen (58404)

“…(E) Analysis of decay time constant (τ) was performed on averaged mEPSCs obtained from 50 individual events. The decay time was best fitted with a single exponential function. …”

Data Sheet 1_Postoperative pain outcomes following uniportal vs. multiportal video-assisted thoracoscopic surgery: a systematic review and meta-analysis.pdf by Fahim Kanani (22589672)

“…Uniportal VATS significantly reduced pain at 24 h (SMD −0.98, 95% CI −1.12 to −0.84, p < 0.0001), equating to a reduction of 2.5 points on a 10-point scale. …”

Contour plots showing how the prevalence of escape amongst A) HLA matched hosts and B) all hosts varies according to the escape and reversion rate. by Helen R. Fryer (194033)

“…The contours show that the prevalence of escape amongst A) HLA-matched hosts and B) all hosts increases as the rate of escape increases and the rate of reversion decreases; however, the increase in escape prevalence in HLA-matched hosts with reversion rate is limited when revision takes an average of 10 years or less. …”

Data Sheet 1_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 2_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Using an ideal observer analysis to investigate the visual perceptual efficiency of individuals with a history of non-suicidal self-injury when identifying emotional expressions by Laura Ziebell (8393820)

“…An increased likelihood of mistaking angry for happy expressions and a decreased likelihood of mistaking sad for surprised expressions were recorded for the HNSSI group compared to controls. …”

Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3‑D <i>in Vitro</i> Model of Neurodevelopment by Josi M. Herron (8068040)

“…By using immunostaining and cell cycle analysis, we found that both BACs induced apoptosis and decreased proliferation of NPCs. To explore the mechanisms underlying their effect on neurosphere growth, we carried out RNA sequencing on neurospheres exposed to each BAC at 50 nM for 24 h, which revealed the activation of the integrated stress response by both BACs. …”

Table_1_Feasibility and assessment of self-reported dietary recalls among newly diagnosed multiple sclerosis: a quasi-experimental pilot study.docx by Solange M. Saxby (14455935)

“…From baseline to 12 months, the HB group had a decreased mean ratio in total grains (0.64; 95% CI 0.43–0.93; p = 0.02) and added sugars (0.52; 95% CI 0.35–0.75; p ≤ 0.001), and an increased mean ratio intake of cured meats (1.74; 95% CI 1.05–2.90; p = 0.04); whereas, the SOC group had a decreased mean ratio intake for beef, veal, pork, lamb, and game meat (0.60; 95% CI 0.40–0.90; p = 0.01). …”

Table_1_Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study.docx by Chengwei Fu (12129339)

“…Real taVNS was associated with a widespread decrease in ALFF in the right hemisphere, including the superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus (voxel p < 0.001, GRF corrected). …”

Supplementary Material for: Practical Value of Anti-Xa Activity in the Evaluation of Extracorporeal Circuit Anticoagulation during Haemodialysis: Results of a Cross-Sectional Singl... by Coene K.L.M. (4545349)

“…<b><i>Conclusion:</i></b> Anti-Xa activity measurements during dialysis can identify patients in whom LMWH dosage should be lowered in a subsequent dialysis session. Whether such an intervention leads to a decrease in haemorrhagic complications needs to be evaluated in prospective studies.…”

Table_1_Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target.xlsx by Sagar Sanjiv Desai (11634628)

“…Modelling of the IRAK1 mutation showed a decrease in its binding to known IRAK1 inhibitors.…”

Table_1_Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study.docx by Chengwei Fu (12129339)

“…Real taVNS was associated with a widespread decrease in ALFF in the right hemisphere, including the superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus (voxel p < 0.001, GRF corrected). …”

Table_1_Immediate modulatory effects of transcutaneous vagus nerve stimulation on patients with Parkinson’s disease: a crossover self-controlled fMRI study.docx by Chengwei Fu (12129339)

“…Real taVNS was associated with a widespread decrease in ALFF in the right hemisphere, including the superior parietal lobule, precentral gyrus, postcentral gyrus, middle occipital gyrus, and cuneus (voxel p < 0.001, GRF corrected). …”

Data Sheet 1_Impact of finerenone on chronic kidney disease progression in Chinese patients with type 2 diabetes: a FIGARO-DKD subgroup analysis.docx by Ping Li (31981)

“…Finerenone resulted in a numerical decrease in the risk of the cardiovascular composite outcome (hazard ratio 0.91; 95% confidence interval 0.50–1.67) and a significantly reduced risk of the key secondary kidney outcome (hazard ratio 0.48; 95% confidence interval 0.29–0.79; p = 0.0029). …”

Presentation_1_Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target.pptx by Sagar Sanjiv Desai (11634628)

“…Modelling of the IRAK1 mutation showed a decrease in its binding to known IRAK1 inhibitors.…”

Additional file 3 of C. elegans as a test system to study relevant compounds that contribute to the specific health-related effects of different cannabis varieties by Monique van Es-Remers (13895294)

“…In this assay C. elegans was exposed to different concentrations (5, 50 and 100 μg/mL) of the Non-Polar Fractions both in carboxylated (NPFdec) and non-decarboxylated (NPF) form. …”