Characterization of the Osteoblast and Chondrocyte Phenotype in Wise^−/− Mutants. by Debra L. Ellies (557960)

“…(B) Active osteoblast cell proliferation as detected using BrdU in a 1.5 month mouse. <i>Wise</i>^−/− mutants display a significant (asterisk) 2.9 fold increase in active osteoblast proliferation of long bones at 1.5 months. …”

Schematic representation of the events following PBS injection and hyper-activation of EGFP expression. by Claire Hippert (171005)

“…The ensuing events also result in either <i>de novo</i> uncoating of encapsidated virions or reactivation of transcriptionally-silenced genomes leading to activated EGFP expression (consistent with the 65-fold increase in EGFP mRNA levels). …”

NDR1 suppresses TGFβ-repression of cell proliferation. by Isabelle Pot (427025)

“…Each point is the mean+SEM (n = 7) of the percent decrease in population growth by TGFβ. …”

Toll signaling in the Drosophila larval fat body shifts programs of anabolic lipid metabolism and dysregulates nutrient storage by Brittany Martínez (8728753)

“…However, we observe 50% decreases in fat body transcript levels of both <i>lipin</i>, a phosphatidic acid phosphatase,<i> </i>and<i> midway, </i>the homolog of diacylglycerol acyltransferase, both of which carry out triglyceride synthesis. …”

Effect of park prescriptions with and without group visits to parks on stress reduction in low-income parents: SHINE randomized trial by Nooshin Razani (4857142)

“…In multivariable analysis, each unit increase in park visits per week was associated with a significant and incremental decrease in stress (change in PSS10–0.53; 95% CI [-0.89, -0.16]; p = 0.005) at three months.…”

Heatmap visualization of protein and transcriptional Dube3a dependent changes. by Laura Jensen (405470)

“…<p><b>A)</b> Fold change for proteins identified as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061952#pone-0061952-g001" target="_blank">Figure 1</a> was calculated using fluorescent intensity as compared to <i>Heatshock</i>-GAL4 alone or w- extracts. …”

FGFR2b-ligands signaling controls cell proliferation in the mesenchyme of the limb bud. by Soula Danopoulos (346564)

“…Mann-whitney non-parametric test was performed. *p≤0.05. Scale bar A–H: 50 µm.</p>…”

Normalized fluorescence of calcium indicator Fluo-4 with and without addition of calcium chelator EGTA. by Stefan Kalies (388164)

“…<p>a) Fluorescence images at different points in time referring to supplemental video <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124052#pone.0124052.s006" target="_blank">S2 Video</a>. …”

CSF/plasma levels, transthyretin stabilisation and safety of multiple doses of tolcapone in subjects with hereditary ATTR amyloidosis by Yusuke Takahashi (19844)

“…<p>To investigate the effect of tolcapone on cerebrospinal fluid (CSF) transthyretin (TTR) tetramer stability in patients with hereditary transthyretin (ATTRv) amyloidosis.</p> <p>A total of 9 patients were enrolled in the study (3 men, 50.3 ± 14.4 years old). …”

The changes of urinary levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). by Yuan-Hong Jiang (398786)

“…<p>The urinary levels of NGF (pg/ml) and BDNF (pg/ml) were compared between baseline and after 6-month treatment of HA (6M) in responders and non-responders based on (A) a visual analogue scale (VAS, for pain) decrease of ≥ 2, (B) global response assessment (GRA) increase of ≥ 2 and (C) functional bladder capacity (FBC) increase of ≥ 50%. …”

Quantification of nAChRs in patient’s biopsied muscle. by Asma Ben Ammar (290015)

“…(<b>B</b>) The nAChR γ-subunit mRNA level, which is synonymous with denervation, was measured in the extrasynaptic zone in patient and was increased by 5-fold compared with the control. The mean value of control AChR (A) or AChR γ-subunit mRNA levels were defined as 1 in arbitrary units. …”

Influence of DMF and MMF on NO production of LPS stimulated microglia. by Darius Moharregh-Khiabani (212285)

“…<p>After stimulation for 24 h with 10 ng/ml LPS a dose dependent decrease of NO production in cells incubated with DMF (5, 10, 50µM/ml) could be observed. …”

Supplementary Material for: Presence of Kidney Disease as an Outcome Predictor in Patients with Pulmonary Arterial Hypertension by Bitker L. (4875295)

Sholl analysis and spine density analysis in mouse hippocampal neurons. by Qiang-qiang Xia (8060987)

“…WT N = 50/10 cells/mice; HET N = 50/10). *P<0.05, **P<0.01, ***P<0.001, unpaired student’s t-test; graphs depict mean ± SEM. …”

Dephosphorylation of ERK1/2 is involved in the WIN-induced down regulation of MMP-9 mRNA, but not in the effect of WIN on MMP-9 protein. by Svantje Tauber (121637)

“…WIN treatment resulted in a dephosphorylation of ERK associated with inhibition of secretion, intracellular accumulation and decrease of MMP-9 mRNA (lanes 1 and 2). …”

miRNA Expression in Endometrium and Trophoblast. by Jocelyn M. Wessels (337687)

“…A negative fold change indicates a decrease in the miRNA in endometrium. …”

Alterations in tone and FM sweeps evoked activity during repetitive stress. by Ghattas Bisharat (20706928)

“…There was a decrease in activity during repetitive stress (mean ± SE, 2-way ANOVA condition F = 13.9, <i>p</i> = 2.03 × 10⁻⁰⁴, condition: intensity interaction F = 4.3, <i>p</i> = 0.01, nested ANOVA (mouse nested within session) F = 2.1, <i>p</i> = 0.001 condition: intensity interaction F = 2.1, <i>p</i> = 0.001), especially at moderate sound intensities (post hoc 50 dB <i>p</i> = 2.36 × 10⁻⁰⁴, but not at lower 30 dB <i>p</i> = 1 or higher intensities 70 dB <i>p</i> = 1 Bonferroni corrected). …”

Knockdown of <i>Lmo4</i> in the BLC leads to enhanced freezing to the context and the cue. by Rajani Maiya (123315)

“…B) Immunohistochemical analyses revealed a robust decrease in LMO4 expression in GFP positive/infected cells (arrows point to infected neurons, right panel) from shLmo4-injected mice but not from shScr-injected mice (arrows point to infected neurons, left panel). …”

The Cd content, chlorophyll content, and SOD and CAT activities changes under Cd stress in <i>M</i>. <i>lutarioriparia</i>. by Jia Wang (51945)

“…One enzyme unit (U) was equal to the amount used to inhibit 50% of the photochemical reduction of NBT, and a decrease in absorbance of 0.01 at OD240 nm minute−1 was considered to indicate 1 U of CAT activity. …”

Effect of Nutrient Restriction and Re-Feeding on Calpain Family Genes in Skeletal Muscle of Channel Catfish (<em>Ictalurus punctatus</em>) by Elena Preziosa (391490)

“…Starvation of channel catfish (average weight, 15–20 g) for 35 days influenced the expression of <i>clpn1</i> (2.3-fold decrease, P<0.05), <i>clpn2</i> (1.3-fold increase, P<0.05), and <i>clpn3</i> (13.0-fold decrease, P<0.05), whereas the subsequent refeeding did not change the expression of these genes as measured by quantitative real-time PCR analysis. …”