Activity of the small molecule PLK1, 2, and 3 inhibitor BI 2536 in preclinical models of MM in the absence of the bone microenvironment. by Douglas W. McMillin (348456)

“…<p>(A) BI 2536 (0–80 nM; 72 hrs) was tested against a panel of MM cell lines by MTT assay, the majority having IC50 values <40 nM. …”

Table 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Data Sheet 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Table 2_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Table 4_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Table 3_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Image 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.pdf by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Non-contributory pension programs and frailty of older adults: Evidence from Mexico by Emma Aguila (3461918)

Contrasting effects of necrotrophic and biotrophic plant pathogens on the aphid Aphis fabae by Al-Naemi, F.

“…However, sequential plant infection (pathogens applied 5 days apart) led to a 70% decrease in fecundity and 50% reduction in intrinsic rate of increase. …”
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Hypoxia and hyperoxia alter NO levels and can drive vasodilation and vasoconstriction. by William Davis Haselden (9175156)

“…<p>All simulations in this figure used a dynamic model. In these simulations we varied arterial oxygen concentration, and the baseline diameter of the vessel was 50μm. …”

SU86.86 cells exhibit phenotypic and genotypic changes following selection by IH. by Daniel Verduzco (712932)

“…A significant decrease in expression of E-cadherin (A) and p53 (B) was detected by quantitative Real-Time PCR. …”

Postsynaptic structural and functional changes induced by NMDA-evoked LTD. by Barbara Calabrese (553229)

“…(<b>D₂</b>) Time montage of an individual spine expressing Lifeact-RFP and eGFP at indicated time points following nLTD induction (time ‘0’ = start of NMDA addition). …”

Table_1_Neuromodulation With Thoracic Dorsal Root Ganglion Stimulation Reduces Ventricular Arrhythmogenicity.pdf by Yuki Kuwabara (8964737)

“…</p><p>Conclusions: In a porcine model, we show that thoracic DRGS decreased cardiac sympathoexcitation and indices associated with ventricular arrhythmogenicity during programmed ventricular extrastimulation. …”

Relationship between fat distribution, iron status, and hepcidin in Qatari obese adults by Abdelhamid, kerkadi

“…We noted a decrease in ferritin, Hemoglobin, serum iron and RBC with an increase in % fat. …”
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Effect of MEHP and PMA on the gene transcription of TSPO, PKCε, PPAR-α, PPAr-β/δ, and PPAR-γ. by Enrico Campioli (336888)

“…Cells were seeded for 24 h before treatment with MEHP (A–C) or PMA (D) and collected after the indicated time points (A) or after 4 days (B–D). qRT-PCR results are normalized to RPS18, expressed in terms of mean and S.E.M. calculated from 3 independent experiments, and presented as fold increase or decrease compared to control. …”

B220 expression as an immunological marker for differentiation of Feline Leukemia Virus carrying cats by Isadora Duarte Santos Frota (10441492)

Nanomediated Stimulation: An Alternative to Brassinolide Hormone Replacement Therapy for Plant Resistance Activation by Hui Feng (174331)

Are <i>Elaeagnus umbellata </i> invasions limited by microbial mutualists? by Scott Meiners (8344812)

Parameters of VMR separated by light or dark periods run at 6 dpf. by Morgan Barnes (7876373)

“…There is a significant decrease in distance moved in the dark (p < 0.0001) and light periods (p < 0.0001), a decrease in velocity in the light (p < 0.001) and dark periods (p < 0.01), a decrease in activity state in the light (p < 0.01) and dark periods (p < 0.001) and an increase in distance to point in the light period (p < 0.01) in the 24 + fish. …”

High-Throughput Screening of Australian Marine Organism Extracts for Bioactive Molecules Affecting the Cellular Storage of Neutral Lipids by James Rae (210551)

“…Screening an <em>n</em>-butanol extract library from Australian marine organisms we identified 114 extracts that produced either an increase or a decrease in LD formation in fatty acid-treated A431 cells with varying degrees of cytotoxicity. …”