Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27 by Yohann Bernard (198579)

“…Administration of our lead compound (FL3) to mice attenuated cardiomyocyte apoptosis and cardiac fibrosis, as reflected by a 50% decrease of mortality.</p> <h3>Conclusions/Significance</h3><p>These results suggest a prophylactic potential of flavaglines to prevent doxorubicin-induced cardiac toxicity.…”

The effect of stretch on the MAP of the fish heart. by Simon M. Patrick (364948)

“…MAPD is shown at MAPD25 (A,D), MAPD50 (B,E) and MAPD90 (C,F) (mean ± S.E.M, <i>p</i><0.05). …”

Averaged traces of laser Doppler flowmetry in C57BL/6J and IP₃R2-KO mice. by Norio Takata (49477)

“…Each experimental condition has N>5 animals. Upon 200 µA stNBM, the cerebral blood flow (CBF) showed an immediate increase, followed by a transient decrease that overshot the baseline both in WT (<b>A</b>) and KO (<b>E</b>). …”

Independent model predictions versus experimental observations. by Ryan Tasseff (253998)

“…The ensemble predicted an approximate 50% decrease in androgen stimulated PSA expression due to AR knock-down 72 hours after treatment. …”

Involvement of serine/threonine kinase type I receptors. by Lauriane Sèdes (490693)

“…Only GCs transfected with siRNA against <i>Bmpr1a</i> present a significant decrease of AMH response.…”

Following treatment with BMP-7 polarization of monocytes into M2 macrophages increases as well as expression of anti-inflammatory markers. by Crystal Rocher (500661)

“…Scale bar  = 50 µm. Histogram B shows quantitative analysis of the percentage of cells expressing CD206 with a significant increase in the ACM+BMP7 group and a significant decrease in the ACM and ACM+BMP7+Foll groups; n = 5–6. …”

Evaluation of Basic Education teachers’ graphic literacy at training and profesional action by Francisco Rodríguez-Alveal (5550914)

“…However, the percentages decrease to 61.3% in the future professors and to 50% in the professors in active, because it is a histogram, representation widely used to show the distribution of quantitative information in any course of statistics at national and international level. …”

Assembly of Drosophila Centromeric Chromatin Proteins during Mitosis by Barbara G. Mellone (134260)

“…Pulse-chase experiments show that CID and CENP-C levels decrease by 50% at each cell division, as predicted for semi-conservative segregation and inheritance, whereas CAL1 displays higher turnover. …”

Morphological changes in NFs for RF-induced rat sciatic nerve injury. by Samjin Choi (358532)

“…CO, control; SH, sham; PRF, pulsed RF; CRF, continuous RF. Scale bar = 50 µm. (B) Definition of NFs for counting. M, myelin; A, axon. …”

Cas4 family proteins are 5′-3′ exonucleases. by Jing Zhang (23775)

“…A marked decrease in cleavage of the labelled oligonucleotide was observed, suggesting that Sso0001 is not highly processive, but can dissociate from substrates following each round of catalysis.…”

Morphological changes of yeast (<i>Saccharomyces cerevisiae</i>) cells after treatment with vanillin. by Aya Iwaki (406491)

“…For dose-dependency, wild-type cells were grown in YPD medium containing 0.00, 0.25, 0.50, 0.75 and 1.00 mM vanillin. For time dependency, time-course data were acquired as described in (A). …”

P3490 specifically detects pS137-PFN1 via immunofluorescence staining. by Jieya Shao (253931)

“…<i>D</i>, HEK293 cells were transiently transfected with Myc-tagged PFN1(wt, S137A or S137D), treated with 50 µM hydroxyfasudil for 16 hr, and double stained with an anti-Myc (red) and P3490 (green) antibodies. …”

Activation of deep SC neurons recapitulates delayed LER in <i>Setd5</i>^<i>+/−</i> animals. by Laura E. Burnett (18794525)

“…(<b>l</b>) Proportion of trials at different contrast looms that show an increase (white), decrease (black), or no change (grey) in speed upon light activation (20%: <i>p</i> = 0.698; 50%, <i>p</i> = 0.026; 98%, <i>p</i> = 0.021, X² test of independence). …”

Table_2_The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.XLSX by Yuxiao Zeng (770249)

“…It demonstrated that the formation rate of the hERO-derived neural retina (NR) was affected by PM2.5 in a concentration dosage-dependent manner. The areas of hEROs and the thickness of hERO-NRs were significantly reduced after PM2.5 exposure at the concentration of 25, 50, and 100 μg/ml, which was due to the decrease of proliferation and the increase of apoptosis. …”

Data_Sheet_1_The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.DOC by Yuxiao Zeng (770249)

“…It demonstrated that the formation rate of the hERO-derived neural retina (NR) was affected by PM2.5 in a concentration dosage-dependent manner. The areas of hEROs and the thickness of hERO-NRs were significantly reduced after PM2.5 exposure at the concentration of 25, 50, and 100 μg/ml, which was due to the decrease of proliferation and the increase of apoptosis. …”

Table_1_The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.XLSX by Yuxiao Zeng (770249)

“…It demonstrated that the formation rate of the hERO-derived neural retina (NR) was affected by PM2.5 in a concentration dosage-dependent manner. The areas of hEROs and the thickness of hERO-NRs were significantly reduced after PM2.5 exposure at the concentration of 25, 50, and 100 μg/ml, which was due to the decrease of proliferation and the increase of apoptosis. …”

Knockdown of NT-3 in <i>Fmr1</i> KO astrocytes rescued aberrant neuronal morphology. by Qi Yang (108283)

“…<p>A, GFP-positive astrocytes indicated the successful infection of NT-3 shRNAs. …”

Table_3_The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.XLSX by Yuxiao Zeng (770249)

“…It demonstrated that the formation rate of the hERO-derived neural retina (NR) was affected by PM2.5 in a concentration dosage-dependent manner. The areas of hEROs and the thickness of hERO-NRs were significantly reduced after PM2.5 exposure at the concentration of 25, 50, and 100 μg/ml, which was due to the decrease of proliferation and the increase of apoptosis. …”

Video_2_Breathing and Coughing: The Extraordinarily High Degassing of Popocatépetl Volcano Investigated With an SO2 Camera.WMV by Robin Campion (5872835)

“…The second type (E2), which corresponds to the strongest events, is anticipated by a rapid decrease of the SO₂ flux to abnormally low values and is followed by a return to its normal values. …”

Data_Sheet_1_Reducing the Cut-Off Value of the Fecal Immunochemical Test for Symptomatic Patients Does Not Improve Diagnostic Performance.PDF by Mercedes Navarro (460391)

“…Reducing the cut-off value to 10 μg/g yielded similar NPV results, with a decrease in specificity. Using a combination of symptoms with a positive FIT result did not improve FIT performance. …”