Reduction of OPL and decreased number of horizontal cells in P18 Oc-deficient mice. by Michaela Kreplova (9239560)

Insulin ICV injection (14 mU) decreases olfactory detection in fasted rats. by Pascaline Aimé (293920)

“…The mean olfactory detection indexes were not statistically different (paired t-test, p¹>0.05, ns; n = 11). (<i>C</i>) Insulin ICV injection (14 mU) decreases olfactory detection. …”

Inhibition of COX isoforms on murine norovirus (MNV) infection leads to decreased MNV replication. by Mia Madel Alfajaro (572993)

Caspase-9 silencing decreases the expression of neuronal markers in differentiating NT2 cells. by Giuseppa Pistritto (299715)

“…<p>NT2 cells stably transfected with scrambled si-RNA or with caspase-9 si-RNA (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036002#s2" target="_blank">Material and Methods</a> section) were harvested at the indicated time points during RA treatment. …”

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

“…<p>(A) Ki-67 expression in parathyroid glands of rats with CKD-induced sHPT treated with Cinacalcet either early in the inactive light phase (<i>Cina1</i>; N = 10) or early in the active dark phase (<i>Cina2</i>; N = 9) compared to untreated rats with sHPT investigated at similar time points (<i>PNX1</i>; N = 7 and <i>PNX2</i>; N = 7, respective) and to normal rats investigated at similar time points (<i>ctrl1</i>; N = 9 and <i>ctrl2</i>; N = 7, respective). …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Nasal mucociliary clearance was decreased in <i>Ttll1</i>^−/− mice. by Toshiyuki Iwata (419270)

“…<p>(A) Tosufloxacin (50 mg/kg) was administered to <i>Ttll1</i>^−/− mice with rhinosinusitis to inhibit cough for 7 days. …”

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. by Sung Won Lee (222509)

KCl treatment increases Elk1 SUMOylation and decreases katanin-p60 expression. by Ece Selçuk (436963)

Behavioral response to ambiguous conditioned fear cues is decreased in adult neurogenesis-deficient mice. by Lucas R. Glover (3912628)

nLTD decreases the molecular proximity between endogenous spine cofilin and F-actin by Barbara Calabrese (553229)

“…<p>. (<b>A</b>) Two examples from control cultures illustrate that endogenous cofilin is present both in neurons (MAP2-positive) and astrocytes (GFAP-positive) <i>Yellow arrows</i> point to astrocytic GFAP-positive processes, which often express levels of endogenous cofilin greater than or equal to that in neurons. …”

VEEV CPD shows decreased phosphorylation of capsid and replication is not sensitive to loss of PKCδ. by Brian D. Carey (6092747)

Swimming and swarming motility phenotypes of single gene deletion mutants putatively decreasing motility. by Julia Andrea Deditius (782678)

AMPs are increased in lesional HS, but DCD and other sweat-gland associated proteins are decreased. by Margaret Coates (6058580)

“…<p>(A) Volcano plot showing increased or decreased genes in HS. …”

Scrub typhus point-of-care testing: A systematic review and meta-analysis by Kartika Saraswati (5007164)

“…<div><p>Background</p><p>Diagnosing scrub typhus clinically is difficult, hence laboratory tests play a very important role in diagnosis. As performing sophisticated laboratory tests in resource-limited settings is not feasible, accurate point-of-care testing (POCT) for scrub typhus diagnosis would be invaluable for patient diagnosis and management. …”

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…Anthropogenic activities, particularly land use change and management practices, alter the global nitrogen (N) cycle. As a central part of the global N cycle, soil N supply from net N mineralization (NNM) and net nitrification (NN) contributes to over 50% of crop N uptake. …”

Decreased sensitivity of coculture HIV spread to RAL predicts multiple infections per cell. by Mikaël Boullé (3329427)

“…Blue dashed line represents parametrization of the cell-free infection response to RAL in terms of IC₅₀ (1.9 nM) and hill coefficient (0.7). Red dashed line represents the fit of coculture infection using the decreased sensitivity to RAL (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005964#sec008" target="_blank">Materials and methods</a>). …”

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

“…Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. …”

<i>Mycobacterium tuberculosis</i> thymidylate synthase (ThyX) is a target for plumbagin, a natural product with antimycobacterial activity - Fig 2 by Apurba Sarkar (8399571)

A representative stress-strain curve of a 3D printed PCL/30% (wt.) nHAp scaffold obtained after compressive testing displaying the linear region to derive E () and the point pertai... by Zahra Yazdanpanah (10038944)