Mitochondrial single-stranded DNA binding protein novel <i>de novo SSBP1</i> mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, K... حسب Margaret A. Gustafson (2138056)

"…Recently, two studies have reported pathogenic variants in SSBP1 associated with hearing loss, optic atrophy, and retinal degeneration. Here, we report a 14-year-old Chinese boy with severe and progressive mitochondrial disease manifestations across the full Pearson, Kearns-Sayre, and Leigh syndromes spectrum, including infantile anemia and bone marrow failure, growth failure, ptosis, ophthalmoplegia, ataxia, severe retinal dystrophy of the rod-cone type, sensorineural hearing loss, chronic kidney disease, multiple endocrine deficiencies, and metabolic strokes. mtDNA genome sequencing identified a single large-scale 5 kilobase mtDNA deletion (m.8629_14068del5440), present at 68% and 16% heteroplasmy in the proband’s fibroblast cell line and blood, respectively, suggestive of a mtDNA maintenance defect. …"

Data_Sheet_1_Anaerobic Conversion of Saline Phenol-Containing Wastewater Under Thermophilic Conditions in a Membrane Bioreactor.docx حسب Julian D. Muñoz Sierra (9443015)

"…However, under such harsh conditions, effective biomass immobilization is difficult, limiting the use of the commonly applied sludge bed reactors. In this study, we assessed the long-term phenol conversion capacity of a lab-scale anaerobic membrane bioreactor (AnMBR) operated at 55°C, and high salinity (18 gNa<sup>+.…"

Table2_Exploring the role of Chinese herbal medicine in the long-term management of postoperative ovarian endometriotic cysts: a systematic review and meta-analysis.doc حسب Danni Ding (5571965)

"…The certainty of the evidence was evaluated using the GRADE profiler 3.2. Additionally, we extracted formulation from the included studies, conducting a thorough analysis.…"

Table1_Exploring the role of Chinese herbal medicine in the long-term management of postoperative ovarian endometriotic cysts: a systematic review and meta-analysis.docx حسب Danni Ding (5571965)

"…The certainty of the evidence was evaluated using the GRADE profiler 3.2. Additionally, we extracted formulation from the included studies, conducting a thorough analysis.…"

Table3_Exploring the role of Chinese herbal medicine in the long-term management of postoperative ovarian endometriotic cysts: a systematic review and meta-analysis.docx حسب Danni Ding (5571965)

"…The certainty of the evidence was evaluated using the GRADE profiler 3.2. Additionally, we extracted formulation from the included studies, conducting a thorough analysis.…"

Data_Sheet_2_Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspr... حسب Qian Zhu (191342)

"…<p>This study evaluated the effects of maternal probiotics and synbiotics addition on several traits and parameters in offspring. A total of 64 Bama mini pigs were randomly allocated into the control (basal diet), antibiotic (50 g/t virginiamycin), probiotics (200 mL/day probiotics), or synbiotics (500 g/t xylo-oligosaccharides and 200 mL/day probiotics) group and fed with experimental diets during pregnancy and lactation. …"

Data_Sheet_1_Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspr... حسب Qian Zhu (191342)

"…<p>This study evaluated the effects of maternal probiotics and synbiotics addition on several traits and parameters in offspring. A total of 64 Bama mini pigs were randomly allocated into the control (basal diet), antibiotic (50 g/t virginiamycin), probiotics (200 mL/day probiotics), or synbiotics (500 g/t xylo-oligosaccharides and 200 mL/day probiotics) group and fed with experimental diets during pregnancy and lactation. …"

Physiological and behavioural aspects of climate change vulnerability in ground-foraging passerines inhabiting South Africa’s Tankwa Karoo desert حسب James Short (20291754)

"…Large-billed larks displayed a thermoregulatory capacity comparable to that associated with most desert birds studied to date, possessing a MaxTb of ~ 45°C and an HTL of ~50°C. …"

Data_Sheet_1_Productivity, water and nitrogen utilization of intensified dryland farming with annual forages on the Chinese Loess plateau.PDF حسب Jianqiang Deng (16931472)

"…In comparison to the W-F-W-F cropping system, annual forage planting decreased the average available soil moisture storage by 50.3 mm above the 80 cm soil layer. …"

AOX inhibitor supresses growth of <i>T</i>. <i>hominis</i> cells inside the RK13 host cells at early meront stages of the infection, and affects the ability to infect by the spores... حسب Kacper M. Sendra (14285356)

"…<p>Effects of the two clinically used anti-microsporidian drugs (albendazole, 350 nM; and fumagillin, 200 nM), and an inhibitor of the AOX Colletochlorin B (CCB, 50 μM) on progression of the parasite life cycle were tested in a synchronised time course of infection in <i>T</i>. …"

Interaction between tombusvirus replication proteins and Fis1. حسب Wenwu Lin (7542863)

Table_1_Durability of immune response after SARS-CoV-2 vaccination in patients with chronic liver disease.docx حسب Ruixin Song (15399459)

"…Within 30 days of booster immunization, the positive rates of nCoV NTAb and nCoV S-RBD in patients with CLD rapidly increased from 29.0% and 48.4% at the end of basic immunization to 95.2% and 90.5%, and maintained a high level (defined as the positive rate >50%) until 120 days when the positive rates of nCoV NTAb and nCoV S-RBD were still high at 79.5% and 87.2%, respectively. …"

DataSheet1_Photochemical Reactivity of Humic Substances in an Aquatic System Revealed by Excitation-Emission Matrix Fluorescence.docx حسب Xin-yuan Wang (10888515)

"…The half-life times of C1, C2, and C3 ranged from 6.61–11.77 h to 4.50–8.81 h for FA and HA, respectively. Combining an excitation-emission matrix with FRI and PARAFAC analyses is a powerful approach for elucidating changes to humic substances during their irradiation, which is helpful for predicting the environmental toxicity of contaminants in natural ecosystems.…"

Table_3_Durability of immune response after SARS-CoV-2 vaccination in patients with chronic liver disease.docx حسب Ruixin Song (15399459)

"…Within 30 days of booster immunization, the positive rates of nCoV NTAb and nCoV S-RBD in patients with CLD rapidly increased from 29.0% and 48.4% at the end of basic immunization to 95.2% and 90.5%, and maintained a high level (defined as the positive rate >50%) until 120 days when the positive rates of nCoV NTAb and nCoV S-RBD were still high at 79.5% and 87.2%, respectively. …"

Table_1_Practical Model to Optimize the Strategy of Adjuvant Postmastectomy Radiotherapy in T1-2N1 Breast Cancer With Modern Systemic Therapy.docx حسب Fei-Fei Xu (538090)

"…After a median follow-up of 69 months, the 5-year rate of DFS, BCSS, and LRR in the overall cohort was 90.2%, 97.4%, and 3.6%, respectively. …"

Table_2_Durability of immune response after SARS-CoV-2 vaccination in patients with chronic liver disease.docx حسب Ruixin Song (15399459)

"…Within 30 days of booster immunization, the positive rates of nCoV NTAb and nCoV S-RBD in patients with CLD rapidly increased from 29.0% and 48.4% at the end of basic immunization to 95.2% and 90.5%, and maintained a high level (defined as the positive rate >50%) until 120 days when the positive rates of nCoV NTAb and nCoV S-RBD were still high at 79.5% and 87.2%, respectively. …"

Targeting pan-caspase activation suppresses HIV-1 infection. حسب Jason Segura (14608801)

"…Primary CD8-depleted PBMC were infected with HIV-1_BAL for 6 days in the presence of 50uM indicated caspase inhibitors and analyzed for the accumulation of p24+/CD62L- populations (<b>A</b>) as well as the level of infection using intracellular p24 staining (<b>B</b>). …"

DataSheet_1_Prognostic Value of Leucocyte to High-Density Lipoprotein-Cholesterol Ratios in COVID-19 Patients and the Diabetes Subgroup.docx حسب Yuxiu Wang (8088287)

"…</p>Methods<p>We conducted a multicenter retrospective cohort study involving all hospitalized patients with COVID-19 from January to March 2020 in five hospitals in Wuhan, China. …"

Image_1_T-Lymphocyte Subsets Alteration, Infection and Renal Outcome in Advanced Chronic Kidney Disease.TIF حسب Jiachuan Xiong (748476)

"…The primary outcomes were the major infection and renal outcome.</p><p>Results: A total of 410 CKD patients were enrolled; the average age was 47.25 years. …"

DataSheet_2_WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.docx حسب Wenyan Li (255305)

"…Bioinformatic analyses showed that compared with wild type (WT), WAS knock out (KO)-CD4⁺ TEM cells exhibited increased Simpson index and decreased D50 index (P <0.05); The rank abundance curve of KO-CD4⁺ TEM cells was shorter and steeper than that of WT, and the angle of ^qD and q in KO-CD4⁺ TEM cells was lower than that of WT, while these indexes showed few changes between WT and KO chimeric mice in the CD8⁺TCM population. …"