mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes. by Wakiko Iwata (8600457)

“…<p>(<b>A</b>) Primary cultured podocytes were isolated from <i>Tsc2</i>^{Δ<i>podocyte</i>} and wild-type controls, followed by western blot analyses of TSC2, phospho-4EBP1, LC3B type II, p62, phospho-ULK1, and β-tubulin. …”

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(C) The densitometry analysis of bands representing means ± SDs of three independent experiments (<i>P</i><0.05). (D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. …”

Ivermectin significantly decreases <i>L</i>. <i>loa</i> mf in BALB/c mice. by Rene Bilingwe Ayiseh (6900296)

Diabetic kidney shows decreased klotho expression. by Jeong Suk Kang (7359572)

“…<p>(a) Representative images of the kidney from normal and diabetic biopsies showing the decreased klotho expression in diabetic podocytes by IHC. …”

Decrease of autoantibody levels in highly inflammatory NSG mice. by Henrika Jodeleit (4722312)

Whole sample storing experiment: Mean FECs of day 0, day 1 and day 2 for hookworm, <i>A</i>. <i>lumbricoides</i> and <i>T</i>. <i>trichiura</i>. by Felix Bosch (10024550)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…(<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …”

Effectiveness of interventions to decrease hesitancy. by Maximilian Nicolaus Burger (12969212)

FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma. by Laura L. Stafman (6577184)

“…There was a trend toward decreased Ki67 staining in FTY720-treated tumors (p = 0.29). …”

S1 Data - by Mahmoud A. Alomari (14780446)

Subjects:

50 WT 5′ and 3′ terminal nts of the S1 gene are sufficient to package a non-MRV gene into infectious virions. by Debarpan Dhar (724473)

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

“…All groups were compared by Kruskal Wallis test with <i>post hoc</i> test after Dunn with Bonferroni adjustment showing significant decreased Ki-67 labeling index of <i>Cina1</i> compared to <i>Cina2</i> (p = 0.006) and the untreated CKD groups (p = 0.0001 and p = 0.0002, respectively). …”

<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays. by Ling Tian (107492)

“…Whole BM cells were harvested from all cohorts of young <i>Kdm6a</i> conditional KO mice (CD45.2) and mixed with WT competitor marrow (CD45.1 x CD45.2) in a 1:1 ratio, which was then transplanted into lethally-irradiated primary recipient mice (CD45.1). …”

Dose response of airways to Methacholine shows a decreased contractility in <i>GSTCD</i>^-/- mouse lungs following LPS treatment. by Bo Liu (127343)

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. by Xiaowen Jiang (8291814)

Insufficient disulfide bond formation results in a decrease in alkaline phosphatase activity and accumulation of the reduced form of DegP in LCFA-utilizing cells. by Kanchan Jaswal (9542107)

“…The band corresponding to AP is shown (Mol. wt. ~50 kDa). <i>(C) Compromised DsbA-DsbB machinery is responsible for the decrease in alkaline phosphatase activity in cells utilizing oleate</i>. …”

HFD decreases nephrocyte uptake of dextran and albumin. by Aleksandra Lubojemska (10746241)

Stability scores with refinement, no USM decreases, no W. by Jedediah M. Singer (10331212)

“…<p>Effects of guided and random substitutions within GM designs with a maximum sequence identity to any expert-designed protein of less than 50%, when guided substitutions are not permitted to decrease USM EC₅₀ predictions and neither guided nor random substitutions are allowed to change amino acids to tryptophan.…”

Stability scores with refinement, no USM decreases, no AFILMVWY. by Jedediah M. Singer (10331212)

“…<p>Effects of guided and random substitutions within GM designs with a maximum sequence identity to any expert-designed protein of less than 50%, when guided substitutions are not permitted to decrease USM EC₅₀ predictions and neither guided nor random substitutions are allowed to change amino acids to alanine, phenylalanine, isoleucine, leucine, methionine, valine, tryptophan, or tyrosine.…”

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

“…(F) The GluN2B-C456Y mutation decreases the sensitivity to glycine. <i>n</i> = 4 oocytes for WT (EC₅₀ = 0.38 ± 0.017 μM) and 9 oocytes for C456Y (EC₅₀ = 1.13 ± 0.049 μM), **<i>P</i> = 0.007, Mann-Whitney. …”