Insufficient disulfide bond formation results in a decrease in alkaline phosphatase activity and accumulation of the reduced form of DegP in LCFA-utilizing cells. by Kanchan Jaswal (9542107)

“…The band corresponding to AP is shown (Mol. wt. ~50 kDa). <i>(C) Compromised DsbA-DsbB machinery is responsible for the decrease in alkaline phosphatase activity in cells utilizing oleate</i>. …”

Methyl Jasmonate Improves Cadmium Tolerance by Reducing Cadmium Accumulation, Enhancing Cell Wall Immobilization and Modulating Transcriptional Regulation in <i>Malus</i> Rootstock by Siyu Liu (825600)

“…The physicochemical and molecular responses of Malus hupehensis exposed to 0 or 50 μM Cd with or without exogenous 5 μM MeJA or 50 μM ibuprofen (IBU) for 3 d were explored via a hydroponic experiment. …”

<i>I</i>_<i>h</i> activation may increase or decrease the threshold for L5PC action potential firing by a strong apical dendritic input, depending on the location of the... by Tuomo Mäki-Marttunen (388882)

5-HT- induced mitochondrial ROS inhibits <i>P</i>. <i>berghei</i> infection. by Li Gao (131516)

Medium-Ring Keto Bislactams with Antischistosomal Activity by Rongguo Ren (2943366)

“…We identified two compounds with IC₅₀ values < 5 μM against ex vivoSchistosoma mansoni (S. mansoni).…”

Inhibiting Gamma-secretase activity without interfering in Notch signaling: Decreasing the inflammatory response in patients with cutaneous leishmaniasis by Lucas Carvalho (3093042)

“…</b>Monocytes from HS (n= 5) were infected with <i>L. braziliensis</i>in stationary phase (ratio 5:1) and cultured in presence or absence of JLK6 (20µM) for 2, 48 and 72 hours. …”

RNS60 treatment of tMCAo mice decreased microglial activation in the CA3 region of the ipsilateral hippocampus. by Gloria Patricia Baena-Caldas (17721328)

MeV <i>M</i> mRNA quantification in cells treated with an inhibitor of RNA polymerase III. by Pierre Khalfi (7868252)

<i>In vitro</i> activity of aryl-thiazole derivatives against <i>Schistosoma mansoni</i> schistosomula and adult worms by Adriana S. A. Pereira (5900249)

“…After <i>in vitro</i> treatment for five days with 6.25 μM NJ05 or NJ07 separately, we observed a decrease of 30% in schistosomula viability, whilst treatment with NJ05+NJ07 lead to a reduction of 75% in viability measured by ATP quantitation and propidium iodide labeling. …”

Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis by Ying Yang (24175)

“…The viability of U266 and RPMI 8226 cells was significantly inhibited by 10 μM SKPin C1 and the inhibitory effect was enhanced with increasing doses of SKPin C1. In contrast, 50 μM SKPin C1 only marginally decreased viability of normal B lymphocytes in 12 h. …”

p63^TECko mice have decreased TECs and DN1 cells in embryonic mice. by Heather E. Stefanski (5058746)

Synthesis, Biological Evaluation, Structure–Activity Relationship, and Mechanism of Action Studies of Quinoline–Metronidazole Derivatives Against Experimental Visceral Leishmaniasi... by Akanksha Upadhyay (6732857)

“…Among all synthesized derivatives, <b>15b</b> and <b>15i</b> showed significant antileishmanial efficacy against both extracellular promastigote (IC₅₀ 9.54 and 5.42 μM, respectively) and intracellular amastigote (IC₅₀ 9.81 and 3.75 μM, respectively) forms of Leishmania donovani with negligible cytotoxicity toward the host (J774 macrophages, Vero cells). …”

Percentage survival at different time intervals compared to control and LD 50 determination and absorbance [OD] at 48 h, 72 h using MTT assay. by Manoj Limbraj Yellurkar (11467219)

TUNEL staining of testis tissues. by Cao Wang (1500691)

“…**<i>p</i> <  0.01. Scale bar =  50 μm.</p> <p><a href="https://doi.org/10.5061/dryad.pzgmsbcz2" target="_blank">https://doi.org/10.5061/dryad.pzgmsbcz2</a>.…”

Morphological changes in the testis and epididymis. by Cao Wang (1500691)

“…B & F) There were no significant changes in the Vit versus control rats. C & G) PM2.5 rats exhibited sparse germinal layer in the seminiferous tubules, lumenal vacuolation and sperm shedding (black arrow) were observed, and the sperm quantity was significantly decreased. …”

Ultrastructure of mitochondria in germ cells. by Cao Wang (1500691)

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

The cytoplasmic leaflet of the TGN in the Neo1p-depleted <i>cfs1</i>Δ <i>erd1</i>Δ mutant contains PS and decreased level of PI4P. by Mamoru Miyasaka (9187916)

BMDM were infected with <i>L.infantum</i> (LEM3323 WT^PpyRE9/DsRed) for 24 hours followed by treatment with 250 μM PMM or 7.5 μM MIL for 72 hours. by Laura Dirkx (8950205)

The decrease in blood flow disrupts CV pruning. by Lin Wen (557398)