Apicoplast inhibitors decrease global parasite prenylation in the second IDC after treatment. حسب Kit Kennedy (4915510)

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. حسب Xiaowen Jiang (8291814)

Crosslinking decreases the alignment of fibers associated with individual cells migrating out of spheroids. حسب Michael Pamonag (12295175)

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. حسب Marek J. Kobylarz (9292599)

BT9 exhibits a dose- and time-dependent cytotoxic effect on medulloblastoma. حسب Zahra Motahari (6814013)

الموضوعات:

Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor حسب Beatrice Noce (16540800)

الموضوعات:

The inhibitory activity of the most active compounds against Glo-I enzyme with less than 50 µM. Their supportive corresponding docking values on two different protocols are display... حسب MohammedBashar Al-Qazzan (22439236)

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. حسب Sung Won Lee (222509)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. حسب Kevin Yuswan (19845885)

Exposure to low CO₂ levels decreases ER cholesterol levels. حسب Nityanand Bolshette (17396845)

"…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …"

The decrease in blood flow disrupts CV pruning. حسب Lin Wen (557398)

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant حسب Ittipat Meewan (7455041)

"…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …"

Trace-weighted images at b = 50 s/mm². حسب Tobit Führes (12647099)

Cytotoxicity (as of %Control) IC₅₀ value (mean ±SD in µM) of the tested compounds vs. Positive controls Cisplatin and doxorubicin against gastrointestinal and colorectal... حسب MohammedBashar Al-Qazzan (22439236)

miR-200c decreases KLOTHO expression in HK-2 cells by translational repression. حسب Kenichi Morii (6843554)

Competition localization increases with growth rate or the distances between colonies, and decreases with the resource diffusion constant. حسب Jeremy M. Chacón (8259792)

Assessment of exoprotein concentration in a 50-mL culture of MH96. حسب Marion Schoof (11999106)

AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. حسب Anthony L. Gaeta (13272609)

Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. حسب Muriel Rhinn (406515)

Cytotoxicity (as of %Control) IC₅₀ value (mean ±SD in µM) of the tested compounds vs. positive controls Cisplatin and doxorubicin against other malignancy’ cell lines ad... حسب MohammedBashar Al-Qazzan (22439236)