<i>NOTCH3</i> Variants and Risk of Ischemic Stroke by Owen A. Ross (139522)

“…</p> <p>Results</p><p>Sequencing of the 269 SWISS probands identified one (0.4%) with small vessel type stroke carrying a known CADASIL mutation (p.R558C; Exon 11). Of the 19 common <i>NOTCH3</i> variants identified, the only variant significantly associated with ischemic stroke after multiple testing adjustment was p.R1560P (rs78501403; Exon 25) in the combined SWISS and ISGS Caucasian series (Odds Ratio [OR] 0.50, P=0.0022) where presence of the minor allele was protective against ischemic stroke. …”

Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection. by Olga A. Maximova (3115716)

“…Note: (i) pial lymphocytic infiltration (yellow arrows) appeared at 7 dpi (<b>G</b>), increased at 14 dpi (<b>H</b>), and decreased at 21 dpi (returning to the level seen at 7 dpi) (<b>I</b>); (ii) a rare focal lesion (red asterisk in H) with depleted MAP2-IR in the Purkinje cell layer (PCL), granule cell layer (GrCL) neurons, and partially in the molecular layer (ML) is spatially associated with the increased pial lymphocytic infiltration. …”

Simplified depiction of hyperthermia impacts on the intrafollicular complement and coagulation cascade. by Louisa A. Rispoli (8201232)

“…Alpha-2-Macroglobulin (A2M) is an anti-proteinase that complexes with proteinases such as kallikrein [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0227095#pone.0227095.ref050" target="_blank">50</a>] to inhibit proteolytic activity.…”

Productivity, efficiency, and overall performance comparisons between attendings working solo versus attendings working with residents staffing models in an emergency department: A... by Richard D. Robinson (1452979)

Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of <i>Helicobacter pylori</i>-induced atrophic gastritis, autoimmune atrophic gastritis and... by Bryony N. Parsons (469436)

DataSheet1_The integrated analysis of gut microbiota and metabolome revealed steroid hormone biosynthesis is a critical pathway in liver regeneration after 2/3 partial hepatectomy.... by Runbin Sun (141863)

Data Sheet 1_Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care.docx by María Queralt Salas (20517896)

“…</p>Results<p>At first consultation, 102 (26.2%) patients were classified as fit, 248 (61.4%) as pre-frail, and 50 (12.4%) as frail. During the study, 62 (15.2%) patients participated in a pre-habilitation program. …”

Identification of the class of mediators present in the hvKP1 generated conditioned minimal medium and ascites that enhance the growth and/or survival of hvKP1. by Thomas A. Russo (188770)

“…<p>The growth of hvKP1 was assessed at 0, 3, 6, and 24 hours in human ascites (batch 1). <u>Panel A</u>: Ascites was not supplemented (unconditioned) or supplemented with: 1) 5% hvKP1-generated conditioned (cond) ascites (batch 1) or 2) 50% conditioned ascites generated from the <i>E. coli</i> laboratory strain BW25113 and isogenic derivatives deficient in the production of enterobactin (BW25113Δ<i>entB</i> (CGSC#8704), BW25113Δ<i>entC</i> (CGSC#8702)), AI-2 molecules (BW25113Δ<i>luxS</i> (CGSC#10100)), and indole (BW25113Δ<i>tnaA</i> (CGSC#8309)) (batch 1). …”

DataSheet1_Contact varroacidal efficacy of lithium citrate and its influence on viral loads, immune parameters and oxidative stress of honey bees in a field experiment.PDF by Nemanja M. Jovanovic (11606566)

DataSheet4_Contact varroacidal efficacy of lithium citrate and its influence on viral loads, immune parameters and oxidative stress of honey bees in a field experiment.PDF by Nemanja M. Jovanovic (11606566)

Table_1_Liver Transcriptomic Analysis of the Effects of Dietary Fish Oil Revealed a Regulated Expression Pattern of Genes in Adult Female Spotted Scat (Scatophagus argus).DOCX by Tuo Wang (1412575)

“…The expression levels of Foxo1a and Lep, which are involved in the lipid metabolism, decreased significantly in the FO group, which may be related to the lower level of HSI in the FO group. …”

Table 1_Association between abdominal obesity and cognitive decline among Chinese middle-aged and older adults: a 10-year follow-up from CHARLS.docx by Qiong Wu (84327)

“…After controlling for confounders, participants with abdominal obesity were less likely to experience rapid decline (OR: 0.67, 95%CI: 0.51–0.8) and slow decline (OR: 0.81, 95%CI: 0.69–0.95) of cognitive function, compared to those with normal WC. RCS analysis showed a decreased risk of cognitive decline with increasing WC. …”

DataSheet3_Contact varroacidal efficacy of lithium citrate and its influence on viral loads, immune parameters and oxidative stress of honey bees in a field experiment.PDF by Nemanja M. Jovanovic (11606566)

DataSheet2_Contact varroacidal efficacy of lithium citrate and its influence on viral loads, immune parameters and oxidative stress of honey bees in a field experiment.PDF by Nemanja M. Jovanovic (11606566)

Image_1_Changes in gut microbiota composition after 12 weeks of a home-based lifestyle intervention in breast cancer survivors during the COVID-19 lockdown.pdf by Sabrina Donati Zeppa (16917315)

“…</p>Results<p>Beneficial effects of the LI were observed on MD adherence, and cardiometabolic parameters (pre vs post). A robust reduction of Proteobacteria was observed after LI, which is able to reshape the gut microbiota by modulating microorganisms capable of decreasing inflammation and others involved in improving the lipid and glycemic assets of the host. …”

Table_1_Liver Transcriptomic Analysis of the Effects of Dietary Fish Oil Revealed a Regulated Expression Pattern of Genes in Adult Female Spotted Scat (Scatophagus argus).DOCX by Tuo Wang (1412575)

“…The expression levels of Foxo1a and Lep, which are involved in the lipid metabolism, decreased significantly in the FO group, which may be related to the lower level of HSI in the FO group. …”

MVEC:AoAF interactions are dependent on signaling through ALK5. by Rebecca A. Scott (488956)

“…(<b>F</b>) Following treatment with 1 μM A83-01, the number of total cells, MVECs, and AoAFs per mm³ was decreased compared to control cultures on day 14. …”

Liver disease burden and required treatment expenditures for hepatitis C virus (HCV) infection in Thailand: Implications for HCV elimination in the new therapeutic era, a populatio... by Rujipat Wasitthankasem (732723)

“…In areas of both high (12%) and average (2%) HCV viremic prevalence, over half of the patients (52.2% to 62.5%) had advanced liver fibrosis (F3 and F4). A striking percentage of patients with F4 (38.9%) were found in the high-prevalence area, while comparable proportions of advanced liver fibrosis presented in the two areas and disease burden peaked at 50–59 years. …”

DataSheet_1_Characteristics of humoral and cellular responses to coronavirus disease 2019 (COVID-19) inactivated vaccine in central China: A prospective, multicenter, longitudinal... by Youhua Yuan (773291)

“…The positive rate of neutralizing antibodies peaked at 97.7% at 60–90 days, decreased, and stabilized at 82.9% at 181–240 days post-vaccination. …”

Data_Sheet_1_Long-term phenobarbital treatment is effective in working-age patients with epilepsy in rural Northeast China: a 10-year follow-up study.docx by Rongxin Li (3552779)

“…During the first year of treatment, 75.2% of patients experienced a ≥50% reduction in seizure frequency compared with baseline (considered as treatment effectiveness); 53.7% of patients were seizure-free. …”