Image_2_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Celecoxib, a selective COX-2 inhibitor, and aspirin, a non-selective COX-1 and COX-2 inhibitor, are being used as anti-inflammatory, analgesic and anti-pyretic drugs. …”

Flavonoid compound icariin enhances BMP-2 induced differentiation and signalling by targeting to connective tissue growth factor (<i>CTGF</i>) in SAMP6 osteoblasts by Bing Xu (69508)

“…However, little is known about the characteristics of SAMP6 osteoblasts and the associated regulatory roles of icariin.</p><p>Methods</p><p>We isolated and cultured osteoblasts from SAMP6 or SAMR1 mice and compared their proliferation, migration, and differentiation by performing the CCK-8 assay, cell counting assay, EdU staining, cell cycle analysis, ALP staining and activity measurement, Alizarin red staining, and RT-qPCR analysis to measure the levels of osteoblast markers, including RUNX2, Colla1 and Oc. …”

Establishing RNAi in a Non-Model Organism: The Antarctic Nematode <i>Panagrolaimus</i> sp. DAW1 by Anna C. Seybold (3342518)

“…Desiccation-enhanced soaking showed the strongest uptake of FITC and resulted in a significant and consistent decrease of mRNA levels of two of the four tested genes (<i>rps-2</i> and <i>tps-2a</i>), suggesting effective uptake of dsRNA-containing solution by the nematode. …”

A trend in discussions about the endemic blues and daily responsibilities. by Seoyoung Kim (2603596)

Data_Sheet_2_Characteristics of Gut Microbiota in Children With Biliary Atresia After Liver Transplantation.xlsx by Wei Song (30780)

“…Analysis of the GM composition showed a significant decrease in Serratia, Enterobacter, Morganella, Skunalikevirus, and Phifllikevirus while short chain fatty acid (SCFA)-producing bacteria such as Roseburia, Blautia, Clostridium, Akkermansia, and Ruminococcus were increased after LT (linear discriminant analysis > 2, P < 0.05). …”

Image_2_Molecular Mechanisms of Tungsten Toxicity Differ for Glycine max Depending on Nitrogen Regime.TIF by Julian Preiner (5214974)

“…Irrespective of N regime, NR activity and total N decreased with increasing W concentrations. Nodulation and therefore also N₂ fixation strongly declined at high W concentrations, particularly in N fix plants. …”

DataSheet_1_Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice.pdf by Eva-Maria Hanschmann (740672)

“…Thereby redox regulation is part of various cellular processes such as the immune response and Trx proteins have been linked in different disorders including inflammatory diseases. Here, we have analyzed the protein distribution of representative oxidoreductases of the Trx fold protein family—Trx1, Grx1, Grx2, and Prx2—in a murine model of allergic asthma bronchiale, as well as their potential therapeutic impact on type-2 driven airway inflammation. …”

Video 2_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

Table_2_Estimation of the rice aboveground biomass based on the first derivative spectrum and Boruta algorithm.xlsx by Ying Nian (7182995)

“…The findings indicate that (1) as the growth stage progresses, the correlation between rice canopy spectrum and AGB shows a trend from high to low, among which the first derivative spectrum (FD) has the strongest correlation with AGB. (2) The number of feature bands selected by the Boruta algorithm is 19~35, which has a good dimensionality reduction effect. (3) The combination of FD-Boruta-PCR (FB-PCR) demonstrated the best performance in estimating rice AGB, with an increase in R² of approximately 10% ~ 20% and a decrease in RMSE of approximately 0.08% ~ 14%. (4) The best estimation stage is the booting stage, with R² values between 0.60 and 0.74 and RMSE values between 1288.23 and 1554.82 kg/hm². …”

Table_2_Nitrogen Isotope Sclerochronology—Insights Into Coastal Environmental Conditions and Pinna nobilis Ecology.xlsx by Melita Peharda (536604)

Image_2_Distinct mechanisms of allopregnanolone and diazepam underlie neuronal oscillations and differential antidepressant effect.tif by Keiko Takasu (11871422)

The impact of the single exit price policy on a basket of generic medicines in South Africa, using a time series analysis from 1999 to 2014 by Rajatheran Moodley (7109351)

“…</p><p>Results</p><p>Majority of the medicines analysed reflect a substantial decrease in medicine prices immediately after implementation of the pricing regulations as reflected in both the change in level and the change in slope using the interrupted time series analysis.…”

Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling by Heejin Ahn (3173670)

Establishment and characterization of a choroid plexus barrier system. by Bethany A. O’Hara (8532741)

“…<p>A) Barrier development protocol. Cells are maintained at high density (>50% confluence) and used for experiments between passages 30–38. …”

RovA stimulated transcription of its own gene. by Yiquan Zhang (113213)

“…<p>Only the bacterial cells of “shift from 26 to 37°C” at the middle-exponential growth phase were analyzed herein. <b>a) LacZ fusion.</b> A promoter-proximal region 743 bp upstream to 146 bp downstream of <i>rovA</i> was cloned into pRW50 containing a promoterless <i>lacZ</i> reporter gene, and then transformed into WT or <i>ΔrovA</i> to determine the β-galactosidase activity in cellular extracts. …”

Data_Sheet_1_Terpenoid Emissions of Two Mediterranean Woody Species in Response to Drought Stress.pdf by Simon Haberstroh (5543624)

“…Terpenoids may play a protective role under these conditions, however, observations of drought effects on plant terpenoid emissions are controversial ranging from decreased emissions to unaffected or increased release of terpenoids. …”

Table2_Effects of crude oil and gas condensate spill on coastal benthic microbial populations.DOCX by E. Kababu (14118744)

“…Porewater PO₄³⁺ drastically declined throughout the experiment, whereas NO₂⁻ + NO₃⁻ decreased ∼100 days post hydrocarbons addition and then increased in the remaining ∼100 days till the conclusion of the experiment. …”

Image2_Effects of crude oil and gas condensate spill on coastal benthic microbial populations.TIF by E. Kababu (14118744)

“…Porewater PO₄³⁺ drastically declined throughout the experiment, whereas NO₂⁻ + NO₃⁻ decreased ∼100 days post hydrocarbons addition and then increased in the remaining ∼100 days till the conclusion of the experiment. …”

Injection of human mesenchymal stem/stromal cells (hMSCs) suppresses spinal cord injury (SCI) symptoms. by Kazumichi Yagura (4537504)

“…<i>Eno2</i> expression was temporarily decreased on pod 3 in the HBSS-treated group (n = 5 mouse). …”

Change in smooth muscle NO from a dynamic increase in flow. by William Davis Haselden (9175156)

“…<p>Simulations were performed using a static proximal model with a NO production rate in the parenchyma of 0.02 M/s corresponding to 50% GC activity with no flow. …”