Dose-Response of 9-cisRA on C2C12 proliferation and differentiation in the absence and presence of TGF-β1. by Chateen Krueger (204755)

“…C2C12 differentiation was inhibited by 50 pM TGF-β1 in panels C and D. 9-cisRA caused a decrease in the number of nuclei with an IC50 of 8 nM (C). 9-cisRA restored myogenesis in the presence of TGF-β1 with an IC50 of 44 nM (D).…”

Dose-Response of atRA on C2C12 proliferation and differentiation in the absence and presence of TGF-β1. by Chateen Krueger (204755)

“…C2C12 differentiation was inhibited by 50 pM TGF-β1 in panels C and D. AtRA caused a decrease in the number of nuclei with an IC50 of 7 nM (C). …”

HAI-2 deficiency disrupts normal architecture of intestinal epithelium. by Roman Szabo (138655)

“…HAI-2-deficiency is associated with a substantial decrease and a near complete loss of mucin-producing goblet cells (<b>G-H’</b>, arrows) in small and large intestine, respectively. …”

Data_Sheet_1_Bioaugmentation of Native Fungi, an Efficient Strategy for the Bioremediation of an Aged Industrially Polluted Soil With Heavy Hydrocarbons.pdf by María Cecilia Medaura (10502816)

“…Higher TPH and HMW-PAHs biodegradation levels in bioaugmented microcosms were also associated to a significant decrease in acute ecotoxicity (EC₅₀) by Vibrio fischeri bioluminiscence inhibition assays. …”

Hypothetical scheme of the stress response in the brain. by Olena Babenko (186646)

6-OHDA lesion-induced dopamine depletion increases intrinsic excitability of medium spiny neurons. by Karima Azdad (370732)

“…(D) Summary histogram of the mean first spike latency at the 120 pA current pulse illustrating the decrease of the first spike latency induced by 6-OHDA lesion. …”

All-atom molecular dynamics simulation of peptides by Ning Zhu (10901010)

“…<p>The initial structure was built using the LEaP module of AmberTools21, and we will run a total of 4000 minimization steps before starting to run molecular dynamics; 2000 is the steepest decline, followed by the conjugate gradient of 2000. …”

Characterization of LNCaP cell growth cultured within biomimetic hydrogels in normal growth media, RPMI and 10% FBS. by Shirly Sieh (139080)

“…<p>(A) Growth curves of LNCaP cells over 7 days for 2D cultures (left) and 28 days for 3D cultures (right) in normal growth media measured by total DNA content (mean ± SE). …”

DataSheet_1_Temperature and elevated CO2 alter soybean seed yield and quality, exhibiting transgenerational effects on seedling emergence and vigor.docx by Naflath Thenveettil (19262185)

“…Little is known about the combined environmental effect of temperature and CO₂ on seed yield and quality and its future generation.</p>Methods<p>A study was conducted to examine the effect of temperature (22/14°C (low), 30/22°C (optimum), and 38/30°C (high)), and CO₂ (420 ppm (ambient; aCO₂) and 720 ppm (elevated; eCO₂)) on seed yield, quality, and transgenerational seedling vigor traits of soybean cultivars (DS25-1 and DS31-243) using Soil-Plant-Atmospheric-Research facility.…”

Supplementary Material for: Clinical Utility of KidneyIntelX in Early Stages of Diabetic Kidney Disease in the CANVAS Trial by Lam D. (11931392)

“…During a mean follow-up of 5.6 years, 131 participants (9.9%) experienced the composite kidney outcome. …”

Neurotensin activates orexin neurons. by Naoki Furutani (169799)

“…Neurons were current-clamped and the current was stepped from –240 pA to +280 pA (with increments of 40 pA with a duration of 100 ms). …”

Mitotic phenotypes caused by co-depletion of CAMSAP2 and HAUS6. by Naoko Nishizawa (20536299)

“…<p>(A,B) Western blotting for γ-tubulin (A) and HAUS6 (B) in WT and CAMSAP2 KO cells. …”

Epidemiological aspects of American cutaneous leishmaniasis and phlebotomine sandfly population, in the municipality of Monte Negro, State of Rondônia, Brazil by Carolina Bioni Garcia Teles (6044771)

“…RESULTS: There has been a significant decrease in the incidence of ACL of about 50% over the last ten years in the municipality. …”

Feasibility of CT radiomics to predict treatment response of individual liver metastases in esophagogastric cancer patients by Remy Klaassen (3903154)

CDA deficiency leads to excess dCTP, inhibiting PARP-1 activity and leading to UFB formation. by Simon Gemble (168663)

“…(G) (1) CDA deficiency leads to intracellular dCTP accumulation, decreasing basal PARP-1 activity. (2) The decrease in basal PARP-1 activity leads to an increase in unreplicated DNA sequences (preferentially at centromeres and CFS sites). (3) During late G2/early mitosis, some of this unreplicated DNA is probably processed by MUS81-EME1 and ERCC1 nucleases as previously suggested [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref036" target="_blank">36</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref012" target="_blank">12</a>], leading to DNA synthesis during metaphase (EdU foci) and preventing supernumerary UFB formation. (4) Some of the excess unreplicated DNA sequences are not processed by the nucleases, leading to supernumerary UFB formation.…”

Flow chart of calculating the distance of cancer driver genes from large methylation change. by Bugra Ozer (3727279)

“…<p>This figure was created for oncogenes, whereas for tumor suppressors we have searched for decrease in expression at the first step instead of an increase. …”

Video_3_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_4_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_2_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Depleted pool of oNSCs and diminished neurogenesis in embryonic <i>BAF155</i>cKO OE. by Christina Bachmann (3111933)

“…Scale bars = 25 μm (A–C) and 50 μm (D–F).</p>…”