DataSheet_1_Targeting Glutamine Metabolism Ameliorates Autoimmune Hepatitis via Inhibiting T Cell Activation and Differentiation.docx by Qiang Yu (5487)

“…</p>Results<p>JHU083 and DON significantly suppressed the activation of T cells and inhibited the differentiation of Th1/Th17 cells and CTL in vivo and in vitro. Besides, we demonstrated that glutamine metabolism blocking inhibited T cells activation and differentiation through decreasing the mRNA expression of amino acid transporter solute carrier family 7 member 5 (SLC7A5) and mitigating the activation of mTOR signaling.…”

Intranasal Dexmedetomidine as a Sedative Premedication for Patients Undergoing Suspension Laryngoscopy: A Randomized Double-Blind Study by Chengxiang Lu (2793913)

“…We investigate intranasal dexmedetomidine as a sedative premedication for anesthesia recovery in an adult population.…”

DataSheet_1_Human gut microbiota-reactive DP8α regulatory T cells, signature and related emerging functions.pdf by Francine Jotereau (362878)

“…We revealed their potent cytotoxic, chemotactic and IgA-promoting abilities, which were confirmed using in vitro assays. …”

Supplementary Material for: Ultrasound-Guided Retrieval and Position Replacement of a Dislodged Fetal Pleuro-Amniotic Shunt: A Novel Approach for a Known Complication of Feto-Amnio... by Adams T.M. (4151050)

“…Shunt dislodgement into the thoracic cavity can cause prenatal complications from the shunt itself or may necessitate neonatal surgery for removal. We present a case where a novel ultrasound-guided technique was used to replace the dislodged pleural shunt in utero, thereby effectively draining the effusion while simultaneously obviating the need for neonatal surgery and decreasing possible perinatal complications.…”

Psychological health ramifications of sea-level rise among coastal populations by Dr. Sajjad Kabir (19171381)

“…<p dir="ltr">This project examines the impact of sea-level rise (SLR) on the psychological health of coastal populations. We conducted a longitudinal study involving 1,144 participants from various communities with differing vulnerabilities to SLR in Bangladesh. …”

Table_1_LncRNA GAS5 represses stemness and malignancy of gliomas via elevating the SPACA6-miR-125a/let-7e Axis.xlsx by Shuang Wu (148427)

“…We showed that lncRNA-GAS5 expression decreased in high-grade glioma tissues and cells, which might be associated with poor prognosis. …”

DataSheet_1_LncRNA GAS5 represses stemness and malignancy of gliomas via elevating the SPACA6-miR-125a/let-7e Axis.pdf by Shuang Wu (148427)

“…We showed that lncRNA-GAS5 expression decreased in high-grade glioma tissues and cells, which might be associated with poor prognosis. …”

DataSheet_1_New Insights on End-Stage Renal Disease and Healthy Individual Gut Bacterial Translocation: Different Carbon Composition of Lipopolysaccharides and Different Impact on... by Hanane Adda-Rezig (7254509)

“…<p>Chronic kidney disease induces disruption of the intestinal epithelial barrier, leading to gut bacterial translocation. Here, we appreciated bacterial translocation by analyzing circulating lipopolysaccharides (LPS) using two methods, one measuring only active free LPS, and the other quantifying total LPS as well as LPS lipid A carbon chain length. …”

Expression and distribution of angiotensin and ACE in the kidneys of control (CON) and SCD (SCD) mice. by Pamela L. Brito (12042075)

Data_Sheet_1_A Polysaccharide Purified From Ganoderma lucidum Acts as a Potent Mucosal Adjuvant That Promotes Protective Immunity Against the Lethal Challenge With Enterovirus A71.... by Yu-Li Lin (258478)

“…It is known that polysaccharide purified from Ganoderma lucidum (PS-G) can effectively modulate immune function. Here, we used PS-G as an adjuvant with the EV-A71 mucosal vaccine and studied its effects. …”

Quantitative analysis. by Miao Cheng (4348510)

“…We established a database of DEPs and identified 107 (63 upregulated and 44 downregulated) between group B and group A, 78 (16 upregulated and 62 downregulated) between group D and group C, 45 (8 upregulated and 37 downregulated) between group D and group B, and 57 (33 upregulated and 24 downregulated) between group C and group A. …”

Autosomal Dominant Hypercalciuria in a Mouse Model Due to a Mutation of the Epithelial Calcium Channel, TRPV5 by Nellie Y. Loh (278148)

“…We identified a mouse with autosomal dominant hypercalciuria (HCALC1). …”

Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction by Daohai Du (1714372)

“…Disruption of EZH2–embryonic ectoderm development (EED) protein–protein interaction (PPI) is a new promising cancer therapeutic strategy. We have previously reported the discovery of astemizole, a small-molecule inhibitor targeting the EZH2–EED PPI. …”

Image_6_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.jpg by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”

Image_5_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.jpg by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”

Image_1_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.jpg by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”

Table_2_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.pdf by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”

Image_2_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.jpg by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”

Image_4_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.jpg by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”

Table_1_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.pdf by K. M. Hudock (14369595)

“…<p>Neutrophil extracellular traps contribute to lung injury in cystic fibrosis and asthma, but the mechanisms are poorly understood. We sought to understand the impact of human NETs on barrier function in primary human bronchial epithelial and a human airway epithelial cell line. …”