Transaldolase deficiency causes a starvation-like response that decreases animal fat content and rewires lipid metabolism gene expression. by Christopher F. Bennett (3875731)

“…<p><b>(A)</b> Intestinal fat staining decreases from RNAi knockdown of <i>tald-1</i> or <i>cco-1</i>. …”

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis by Raj Vuppalanchi (458660)

“…Notably, miR-155, a known regulator of liver inflammation, had the highest fold increase in cirrhotic livers (2.2-fold, P=4.16E-08) and significantly correlated with hepatic CYP3A activity (r=-0.50, P=0.017). …”

Clinical features of Type 1 Diabetes (T1D) patients. by Adriana Carvalho-Santos (814114)

Subjects:

LOH resulting in 189R/R produces a strong decrease in drug susceptibility. by Pétra Vande Zande (17628246)

VGB decreased activation of the mTOR pathway in vivo. by Bo Zhang (6559)

The fasting glucose (FG) levels are weakly negatively correlated with APRIL serum levels in diabetic patients. by Adriana Carvalho-Santos (814114)

Subjects:

hESCs-CM decreased cancer cells growth. by Shufeng Zhou (398572)

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…Representative traces of TEA-sensitive potassium currents (1mM). <b>D</b>. TEA-sensitive currents were specifically decreased in PV interneurons from mice that received cuprizone treatment compared to control mice (<i>group x voltage two-way repeated measures: n = 10,14 cells from 5 mice per group: F(13,286) = 5.082, p < 0.0001</i>). …”

Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i>^−/− cells. …”

Trehalose decreased PAN-induced apoptosis in human podocytes. by Yu-Lin Kang (663806)

“…<p>Podocyte were treated with PAN (30 µg/ml) or/and Trehalose (50 mM) for 48 h. (<b>A</b>) Trehalose induced autophagy in PAN-treated human podocytes. …”

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…<b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001230#pbio.3001230.s007" target="_blank">S2 Data</a></b> provides the source data used for all graphs and statistical analyses. …”

TL decreases cell viability in malignant cells dependent of p53 status. by Ajay Kumar (192967)

The three hit compounds decrease bacterial load of <i>Salmonella</i> in mammalian cells. by Abigail L. Reens (5349746)

The ATR-CHK1 inhibitor AZD6738 decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Systemic inhibition of TGF-β decreases retinal smad2 phosphorylation <i>in vivo</i>. by Tony E. Walshe (269700)

“…Scale = 50 µm. (D) Higher magnification of ppsmad2 staining in control mice, demonstrating nuclear pp-smad2 in retinal ECs (arrow). …”

Basal ubiquitination of GlyT2 in neurons decreases when the pool of free monomeric ubiquitin is reduced. by Jaime de Juan-Sanz (386083)

Preliminary dose-response experiments. by Noelia Torremadé (3687523)

Subjects:

Reductions in MEF2 expression do not impair PGE₂ decrease of <i>Sost</i>. by Damian C. Genetos (325684)

Deleting NspA decreases binding of fH to <i>N. meningitidis</i>. by Lisa A. Lewis (244867)

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”