LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”

SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

Subjects:

Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

Subjects:

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. by Jian Zhang (1682)

Fig 2 - by B. Ulfhake (6293984)

Subjects:

HSF2 regulates ORF50 expression in an RTA independent manner. by Lorenza Cutrone (21144285)

Spontaneous oxycodone withdrawal initially flattens NREM power rhythms, decreases low frequency and increases high frequency power. by Michael Gulledge (20577135)

Ammonia (NH₃) measurement (ppm) on the last day of a cage-change cycle in the front, middle and rear of the cage, for each site and sex. by B. Ulfhake (6293984)

Subjects:

PPM1A is critical for proliferation of intestinal organoids. by Ruyuan Zhou (10197187)

“…A dramatic lower number of de novo crypts (D, top panel) and the decreased size of organoids (D, bottom panel) were seen in organoids from PPM1A KO mice, with roughly 50 intestine organoids each group examined. …”

Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

Subjects:

Essential oil-incorporated carbon nanotubes filters for bacterial removal and inactivation - Fig 2 by Xiuli Dong (658906)

NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. by Zhentao Sheng (107495)

“…(J) A proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways through inversely modulating the levels of positive and negative pathway components is shown. Drk/Grb2 and MAPK, two positive components of the EGFR signaling pathway are targeted for degradation by the Arg/N-end rule pathway and E3 ubiquitin ligase Ubr4 while PP2AC, a negative regulator of EGFR signaling pathway, is targeted for degradation by the Ac/N-end rule pathway E3 ubiquitin ligase Cnot4. …”

Conditional <i>Aff4</i> knockout decreases fat mass in mice. by Yaqian Chen (1711576)

HSF2 binds the ORF50 promoter and remodels the local chromatin landscape. by Lorenza Cutrone (21144285)

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…<p><b>(A)</b> Kaplan-Meier survival curve. Tamoxifen was given by gavage for 6 days to mice with the genotype <i>Mll1</i>^{<i>FC/+; Vil-Cre-ERT2/+</i>} (n = 12) and <i>Mll1</i>^{<i>FC/FC; RC/+</i>} (n = 18). …”

PRV-induced infertility is caused by decreased P4 level. by Bing-Qian Su (8616981)

Submandibular gland removal decreases avoidance of bitter taste in mice by Masataka Narukawa (20599511)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA_A-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”

Knockdown of Ube2d proteins decreases ubiquitination of EGFR in HeLa cells. by Mariya S. Liyasova (3821908)