<i>ClvR</i> and split <i>ClvR</i> configurations. by Georg Oberhofer (3401438)

MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of <i>Mycobacterium tuberculosis</i> to lysosomes... by Sanjaya Kumar Sahu (4054438)

“…The transcriptional and post-transcriptional mechanisms that govern the balance between M1 and M2 polarization, and bacteria-containing processes such as autophagy and trafficking of Mtb to lysosomes, are incompletely understood. Here we report for the first time, that the transcription factor KLF4 is targeted by microRNA-26a (miR-26a). …”

Impact Evaluation of a System-Wide Chronic Disease Management Program on Health Service Utilisation: A Propensity-Matched Cohort Study by Laurent Billot (838453)

“…These components were broadly prescribed by the head office of NSW Health, which funded the program, and were implemented by regional health services (local health districts) in ways that best suited their own history, environment, workforce, and patient need. We used a propensity-matched cohort study to evaluate health service utilisation after enrolment in the CDMP.…”

End Stage Renal Disease Predicts Increased Risk of Death in First Degree Relatives in the Norwegian Population by Rannveig Skrunes (3339708)

“…Excluding known hereditary renal disease, aHR decreased to 1.12 (1.09–1.15). Cardiovascular death aHR was 1.15 (1.10–1.21), of which cerebrovascular death 1.34 (1.22–1.50). aHR for death due to non-hereditary renal/ureteric disease was 2.29 (1.81–2.91) with renal failure 1.80 (1.26–2.56) and glomerular disease 5.69 (3.88–8.34) as main contributors. …”

DataSheet_1_MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis.pdf by Jing Hu (41899)

“…Moreover, we identified and confirmed Interferon Induced Protein with Tetratricopeptide Repeats 2 (IFIT2) as a specific target of miR-199a-5p, and silencing endogenous IFIT2 expression alleviated the inhibitory effect of miR-199a-5p antagomir on the osteogenic differentiation of hSCAPs. …”

Prediction of a mark by cross-cell line models. by Tobias Ahsendorf (4669786)

“…(<b>B</b>) Barplot of median Pearson’s r in the cross-cell line setting and the 10-fold CV setting, where we displayed just those marks with a decrease of at least 0.3. …”

Enhanced glycolysis promotes replication of SVA. by Huizi Li (6241586)

S7 Fig - by Magdalena R. Raykova (16455790)

“…This is consistent with the reported potential of the EDTA-Fe(III) redox couple by Allcorn et al. when considered in the context of the Ag/AgCl QRE used here and the scan rate of 50 mV/s [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0287824#pone.0287824.ref061" target="_blank">61</a>]. …”

DataSheet_1_Declining Population Sizes and Loss of Genetic Diversity in Commercial Fishes: A Simple Method for a First Diagnostic.docx by Natalia Petit-Marty (3428546)

“…Thus, this study aims to answer a simple, even naive question, given the complexity of the subject: Could we use a simple method to obtain information on the loss of genetic diversity in exploited fish species? …”

Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells by Kwame Osei-Sarfo (6585389)

“…<div><p>To gain a greater understanding of oral squamous cell carcinoma (OSCC) we investigated the actions of all<i>-trans</i>-retinoic acid (RA; a retinoid), bexarotene (a pan-RXR agonist), and forkhead box (FOX) transcription factors in human OSCC-derived cell lines. …”

Galectin‑9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix by Dharma Pally (7216271)

“…Signaling experiments and unbiased quantitative proteomics revealed Galectin-9 induction of Focal Adhesion Kinase activity and S100A4 expression, respectively. FAK inhibition decreased S100A4 mRNA levels. …”

Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor by Olga Gorelenkova Miller (2900069)

“…We used a rapid screening approach to test 504 novel electrophilic compounds for inhibition of Grx1, which has a highly reactive active-site cysteine residue (pKa 3.5). …”

Cell motility depends on a QSF secreted by cells. by Laurent Golé (198154)

“…<p>The diffusion coefficient is decreasing with cell density and experimental time, highlighting the role played by a QSF factors in cell motion. …”

Stability of a dairy-based electrolyte replenishment beverage by Natali Knorr VALADÃO (6719882)

“…The beverage was processed at 95 °C/50 s (B1), 90 °C/40 s (B2) and 85 °C/30 s (B3), all stored at 25 °C in the dark. …”

Stability of a dairy-based electrolyte replenishment beverage by Natali Knorr VALADÃO (6719882)

“…The beverage was processed at 95 °C/50 s (B1), 90 °C/40 s (B2) and 85 °C/30 s (B3), all stored at 25 °C in the dark. …”

Table 1_Lower phase angle as a marker for poor prognosis in patients with chronic kidney disease: a cohort study.docx by Yi-qin Chen (21497477)

“…When modeled in 2 groups according to the turning point of 5.0°, the adjusted hazard ratios (aHRs; 95% confidence intervals [CIs]) for broad-PhA group was 0.77(0.63, 0.95) compared with narrow-PhA group. …”

ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type by Luca Schifanella (6694940)

“…High Alum dosage, in contrast, elicited serum IgG to V2 that correlated with a decreased risk of Tier 1 SHIV-C acquisition. …”

Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infecti... by Zdenek Hel (337869)

“…Importantly, intestinal secretions of antiretroviral therapy-treated HIV-1-infected individuals exhibited a significant elevation of IgM levels and decreased IgA/IgM and IgG/IgM ratios of antibodies specific to a variety of microbial and food antigens. …”

DataSheet_1_A Regional View of the Response to Climate Change: A Meta-Analysis of European Benthic Organisms’ Responses.csv by George Hoppit (12961253)

“…We found calcifying organisms are an at-risk taxon in European waters, with climate stressors decreasing growth rates, reproduction, and survival rates. …”

Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study by ShaSha Li (12163175)

“…In this current study. we aimed to ascertain if sKlotho could be a diagnostic or prognostic biomarker in this population. …”