HMGA1 is required for migration, invasion, anchorage-independent cell growth, and limiting dilution tumorigenicity. by Amy Belton (118922)

“…<p>(A) Transfection with an shRNA knockdown vector for <i>HMGA1</i> in highly aggressive, poorly differentiated human colon cancer cells (HCT116 and SW480) results in a significant decrease in HMGA1 protein. …”

Adult Hap1 expression reduces the stress-induced defective neurogenesis in the hippocampus and depressive-like behavior. by Jianxing Xiang (724184)

“…Immunostaining of BrdU in the DG was performed 1 day after the final treatment. Scale bar: 50 μm. The stressed groups showed fewer BrdU+ cells than non-stressed groups, and the decrease was more dramatic for stressed KO mice than stressed controls. …”

Summary of phenotypic data of the candidate genes implicated in HR-DSBR. by Mikołaj Słabicki (246635)

“…Genes that decreased GFP levels with a z-score>4 are marked with +. …”

Silencing <i>HMGA1</i> expression halts cell growth and induces dramatic changes in cell morphology and gene expression. by Sandeep N. Shah (118905)

“…<p><b>A</b>) Lentiviral-mediated delivery of shRNA to <i>HMGA1</i> (denoted shHMGA1) results in a marked decrease in <i>HMGA1</i> mRNA and protein in triple negative breast cancer cell lines (MDA-MB-231, Hs578T). …”

Reduced UPEC-mediated inflammatory damage to bladder epithelium with AKB-4924 pretreatment. by Ann E. Lin (502380)

“…<p>(<b>A, B</b>) ELISA analysis shows pro-inflammatory cytokines IL-6, IL-1β or KC in the bladders or kidneys are reduced in AKB-4924 treated mice 18–24 h post UPEC CFT073 infection. …”

Different levels of shade on population of grasshoppers and its oviposition preference on heliconias by Ana Cristina Bittar (4851412)

“…An increase in shade resulted in a decrease in the number of oviposition holes from the grasshopper and the number of lateral buds. …”

EVs obtained from U937 cells increased the expression of adhesion molecules in endothelial cells EA.hy926. by Myriam Lucia Velandia-Romero (8259726)

“…Cells infected with DENV-2 at MOI 0.2 (IC) showed a slight decrease in the expression of VE-Cad, while in cells exposed to <i>P (+ or -)</i> or <i>EV (+ 4G2 or UV)</i> showed a bright fluorescence pattern that delimits the cells. …”

Progressive differences between IPCs and OC surface proportions promoted 2° and 3° formation. by David E. Larson (246516)

“…‘No OC Expansion’, No Death' curve indicates constant OC surface area (no expansion) and no cell death. (<b>C</b>) A graph indicating the decrease in cell number for the different simulations. …”

Data_Sheet_1_Synthetic Fluid Inclusions XXIV. In situ Monitoring of the Carbonation of Olivine Under Conditions Relevant to Carbon Capture and Storage Using Synthetic Fluid Inclusi... by Eszter Sendula (2822699)

“…Magnesite formation was observed within hours at ≥100°C, while at 50°C magnesite nucleation and precipitation was only observed after a few weeks. …”

Inhibition of Cav3 binding affects Ca²⁺ homeostasis, cytoskeletal-membrane interactions and MSC activity. by Haixia Huang (452278)

Simulation-Based Approach to Data Fusion for Three Different Measures of Caspase Activity by John G Albeck (268792)

“…(C) An increase in T_s to 100 min (D) or a decrease in <i>f</i> to 0.1.</p> <p>(E, F, G) Concordance of data on EC substrate cleavage as obtained from immunoblot, flow cytometry, and live-cell assays in HeLa cells treated with 250 ng/ml (E), 50 ng/ml (F), or 10 ng/ml (G) TRAIL. …”

Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation by Nagarjuna Nagaraj (1296663)

“…Reducing the target values from a standard of 30 000 to 5000 ions did not severely affect identification rates but did decrease identification and localization scores for phosphorylation sites. …”

Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation by Nagarjuna Nagaraj (1296663)

“…Reducing the target values from a standard of 30 000 to 5000 ions did not severely affect identification rates but did decrease identification and localization scores for phosphorylation sites. …”

Expression of STUB1DN mutants leads to the formation of protein aggregates. by Joao Vasco Ferreira (7499918)

“…Cells were further incubated in the presence or absence of 10uM of MG-132 and 50nM of BafA for 6h. A) Cell extracts of proteins insoluble in increasing concentrations of SDS where filtered through a nitrocellulose membrane and trapped proteins were blotted with antibodies directed against ubiquitin, p62 and myc tag. …”

Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation by Nagarjuna Nagaraj (1296663)

“…Reducing the target values from a standard of 30 000 to 5000 ions did not severely affect identification rates but did decrease identification and localization scores for phosphorylation sites. …”

Simultaneous PreCaT and extracellular field potential recordings. by Carmelo Sgobio (652457)

“…Effects of application of a cocktail of antagonists of ionotropic glutamate and GABA receptors ((2R)-amino-5-phosphonovaleric acid (APV, 50 µM); 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione (NBXQ, 10 µM)) are also shown. …”

Female motorcycle mortality in Brazilian municipalities, 2005, 2010 and 2015 by Pedro Cisalpino Pinheiro (6070499)

“…In the municipalities of the South and Southeast regions, mainly in the period between 2010 and 2015, there was an apparent decrease in mortality. The percentage variation showed a reduction in the indicator analyzed in the period between 2010 and 2015 for the largest municipalities in the South and Southeast regions. …”

Neutralization by PGT121-137 antibodies and chimeric variants. by Marie Pancera (335526)

“…<p>Strong neutralization is coded in red (>90%), intermediate in yellow (75–90%) and weak in green (50–75%). Neutralization data were generated in single neutralization experiments, with each test sample analyzed in duplicate to determine the percent decrease in virus growth (neutralization) as compared and normalized to the control wells without antibody expression (defined as 0% neutralization). …”

H35N induced cell death and changes in nuclear morphology in presence of pan-caspase inhibitor zVADfmk: by Saumya S. Srivastava (262013)

“…<p>(A) A431 cells either left untreated or treated with H35N (8 µg/ml) or zVADfmk (50 µM) for 2 hr followed by addition of H35N (8 µg/ml) for the indicated time which were then mildly trypsinised and viable cells were counted after staining with trypan blue as mentioned in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006293#s2" target="_blank">materials and methods</a>. …”

Schematic of the filtration setup and flowmeter device used in this study. by Corentin Fournier (5088941)

“…<p>We used overpressure filtration for plankton size-class filtration with three filters in series, (<i>i</i>) a 180-μm nylon net pre-filter to remove zooplankton and larger particles, and (<i>ii</i>) a 5.0-μm and (<i>iii</i>) a 0.2-μm pore-size polycarbonate membrane filter, in order to collect the nanoplankton and picoplankton, respectively, for DNA extraction. …”