Summary of cell-based assay EC50 results for WT BMP9 and A347E variant. by Tobias G. Schips (21799838)

Subjects:

Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7. by Taulant Bacaj (803415)

“…RRP was measured as described in A. <b>C.</b> The decreased RRP size in Syt1/7 double-deficient neurons is rescued by WT Syt1 (Syt1^WT) but not Syt1-containing mutations in the top-loop Ca²⁺-binding sequences (Syt1^C2A*^B*). …”

<i>roh</i> mutation results in Rh1 decrease. by Yu Huang (15093)

“…<p>(A) GFP fluorescence of one-day old wild-type (left panel) and <i>roh</i>^{<i>EY04039</i>} (right panel) flies showing a reduction in Rh1-GFP. …”

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”

PPM1A is critical for proliferation of intestinal organoids. by Ruyuan Zhou (10197187)

“…A dramatic lower number of de novo crypts (D, top panel) and the decreased size of organoids (D, bottom panel) were seen in organoids from PPM1A KO mice, with roughly 50 intestine organoids each group examined. …”

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…(<b>D,E</b>) The channel open probability was evaluated by measuring the degree of MTSEA (200 μM) potentiation using TEVC recordings from <i>Xenopus</i> oocytes expressing the WT GluN2A (<i>left panel</i>) or the mutant GluN2A(D731N) (<i>right panel</i>) coexpressed with GluN1(A652C) at a holding potential of -40 mV in presence of EC₅₀ concentrations of glutamate with saturating concentration (100 μM) of glycine (open bar) and 0.2 mM MTSEA (closed bar). …”

Decreased dendritic spine density and mEPSC amplitude in the DG of Arf4^+/− mice compared to WT mice. by Sachi Jain (108277)

“…(<i>D–F</i>) Electrophysiological recordings reveal a decrease in amplitude of mEPSCs in Arf4^+/− (n = 9 cells) compared to WT controls (n = 6 cells) at 2 months of age. …”

TcMTH and EcMutT parasites effectively decreased DHR oxidation and show increase in antioxidant enzyme expression. by Grazielle R. Goes (2585713)

TMD residues decrease sensitivity. by Ákos Nemecz (356830)

“…Glu residues are color coded based upon effect, with residues in red producing a significant decrease in pH₅₀, and in yellow, an insignificant or weak effect, whereas the dark purple and magenta for His residues are synonymous to the red of Glu residues. …”

Decrease in GABA in APP mice. by Ksenia V. Kastanenka (3692380)

Hematopoietic-restricted loss of Zeb1 decreases hematopoietic colony formation potential and ability to compete with wt HSPCs for contribution to all hematopoietic lineages. by Jueqiong Wang (11467505)

“…<p><b>(A)</b> HSPCs isolated from Vav-iCre; <i>Zeb1</i>^fl/fl fetal livers show decreased numbers of colonies in methylcellulose-based colony assays (first) that further decreases upon secondary replating (second) compared to Cre negative controls. …”

CHIKV-infected primary joint tissue fibroblasts display decreased MHC-I cell surface expression. by Brian C. Ware (8544672)

mTOR activity is decreased in KSR1-deficient T cells. by Marie Le Borgne (337225)

Neurite length in <i>Thap1</i>^<i>+/-</i> and <i>Thap1</i>^{<i>C54Y/+</i>} E16 primary striatal neurons <i>in vitro</i> is decreased relative to neurons from WT mice. by Zuchra Zakirova (431614)

<i>Rbfox3</i> deletion decreased the thickness of the IPL in the retina. by Yi-Sian Lin (3193446)

<i>In vivo</i> expression of EAC3I decreases s/mEPSC frequency in dorsal lateral striatum MSNs. by Jason R. Klug (132807)

PRV and HSV-1 employ US3 to decrease Bclaf1 in a proteasome-dependent manner. by Chao Qin (119135)

WT1 and LANA expression correlate with decreased T cell infiltrates. by Ayana E. Morales (17756335)

Suppression of the growth defects in flippase mutants by decreased synthesis of PI. by Kanako Yamagami (703555)

Thy1-p45 transgenic mice have decreased retraction of CST fibers and improved functional recovery following SCI compared to their WT littermates. by Tsung-Chang Sung (436234)