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41
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
Published 2023“…Objective: In this study, we investigated the anti-cancer potential of Neosetophomone B (NSP-B), a fungal-derived secondary metabolite, on CTCL cell lines H9 and HH. …”
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42
Preparation of Mesoporous/Microporous MnCo2O4 and Nanocubic MnCr2O4 Using a Single Step Solution Combustion Synthesis for Bifunction Oxygen Electrocatalysis
Published 2020“…We report the synthesis of mesoporous/microporous MnCo2O4 and cubic MnCr2O4 using solution combustion synthesis for oxygen reduction and oxygen evolution reactions. …”
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43
Maximum Likelihood Estimation in the Inverse Weibull Distribution with Type II Censored Data
Published 2022“…We consider maximum likelihood estimation for the parameters and certain functions of the parameters in the Inverse Weibull (IW) distribution based on type II censored data. …”
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44
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
Published 2018“…The physical interaction between vasorin and TGF-β1 was significantly decreased in old vs. young VSMCs. Further, exposing young VSMCs to Ang II increased the levels of matrix metalloproteinase type II (MMP-2) activation and TGF-β1 downstream molecules p-SMAD-2/3 and collagen type I production up to the levels of old untreated VSMCs, and these effects were substantially inhibited by overexpressing vasorin. …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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47
Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production
Published 2021“…Hypothesizing that there may be a biochemical link between the two, we examined the potential cross talks of signaling pathways between NKG2D and RKIP. …”
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48
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.
Published 2022“…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …”
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49
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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50
SARS-CoV-2: An Analysis of the Vaccine Candidates Tested in Combatting and Eliminating the COVID-19 Virus
Published 2022“…This paper will aim to educate readers on the processes that the vaccine candidates took, and better understand the procedures; additionally, we’ll look at all candidates’ findings that went into clinical trials, assessing, analyzing, and evaluating the 27 vaccine candidates that went into phase III trials and the 13 candidates that went into either phase I/II trials.…”
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51
Impact of SARS-CoV-2 on Ambient Air Quality in Northwest China (NWC)
Published 2021“…The proportion of air quality Class I improved by 32.14%, and the number of days with PM2.5, SO2, and NO2 as primary pollutants decreased while they increased for PM10, CO, and O3 in 2020. …”
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52
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
Published 2020“…In this study, we explored the anti-cancer effects of different generations and surface chemistries of PAMAMs on HER2-positive breast cancer cell lines. …”
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53
Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events
Published 2021“…We used a 12-yr data set of benthic cover (2005�2017), spanning two bleaching events, to assess changes in benthic cover and coral community composition along 21 islands within Gulf of Mannar (GoM), southeast India. …”
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54
Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…In this work, we present novel conductometric sensors based on graphene and Au nanoclusters that are highly selective to Hg2+ ions. …”
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55
Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate
Published 2020“…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …”
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56
Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO2 conversion to fuels
Published 2024“…Several studies have been reported in both the processes with a desire to decrease the atmospheric CO2 concentration by stopping CO2 emissions at the site of generation itself. …”
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57
Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
Published 2020“…We also show that the RyR2 N-terminus domain interacts with the C-terminal channel pore region in a Ca2+-independent manner. …”
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58
Investigation of flexible polymer-Tl2O3 nanocomposites for x-ray detector applications
Published 2019“…We report on the synthesis and characterization of composite semiconducting polymer – nanoparticle membranes for X-ray detection applications. …”
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59
Type 2 diabetes epidemic and key risk factors in Qatar: A mathematical modeling analysis
Published 2022“…Introduction We aimed to characterize and forecast type 2 diabetes mellitus (T2DM) disease burden between 2021 and 2050 in Qatar where 89% of the population comprises expatriates from over 150 countries. …”
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60
Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity
Published 2021“…In this review, we discuss SARS-CoV-2 reinfection rates in previously infected and vaccinated individuals in relation to humoral responses. …”
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