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661
Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
Published 2015“…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …”
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662
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…We find that monthly shrinkage rates have a pronounced structured variability around the channel network with the shrinkage rate systematically decreasing farther away from the channels. …”
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663
MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.
Published 2021“…We suggested that IRAK3 gene expression in CD14 + monocytes appears to be relevant to the RA etiology and clinical activity, whereas, in this study, MYD88 does not play a role in RA onset and development.…”
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664
Frugal innovation for sustainable rural development
Published 2023“…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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665
The Visibility of Disabilities within Pharmacy Program Recruitment Material.
Published 2020“…Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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Gas solubility and rheological behavior study of betaine and alanine based natural deep eutectic solvents (NADES)
Published 2018“…A pressure driven physisorption mechanism was observed for the studied systems. …”
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669
Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method
Published 2013“…A series of nanostructured Ni-Zn ferrites Ni1-xZn xFe2O4 (x=0, 0.5 and 1) with a grain size from 24 to 65 nm have been prepared with a sol-gel method. …”
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670
Phytoplankton size changes and diversity loss in the southwestern Mediterranean Sea in relation to long-term hydrographic variability
Published 2020“…We show a conspicuous shift in the structure of the phytoplankton community characterized by an increase of small-sized species and diversity loss, revealing a dominance of smaller blooming diatoms and cyanobacteria. …”
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671
Metabolomics Profiling of Stages of Coronary Artery Disease Progression
Published 2024“…This study leveraged metabolomics profiling to investigate the progression of CAD, focusing on the interplay of hypercholesterolemia, hypertension, and diabetes. We performed a metabolomic analysis on 221 participants from four different groups: (I) healthy individuals, (II) individuals with hypercholesterolemia (HC), (III) individuals with both HC and hypertension (HT) or diabetes, and (IV) patients with self-reported coronary artery disease (CAD). …”
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672
Cognitive Balance for Fog Computing Resource in Internet of Things: An Edge Learning Approach
Published 2022“…First, we propose a cognitive balance architecture with a cognition plane, which includes service demand monitoring, policy processing and knowledge storage of cognitive fog resources. …”
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673
Magnetorheological elastomer-based variable stiffness flexible coupling for vibration isolation
Published 2021“…Magnetorheological elastomers (MRE) are smart composite materials whose mechanical properties, such as stiffness, are changed when exposed to a magnetic field. In this article, we report on the fitting of a variable stiffness coupling (VSC) within a shaft to isolate torsional vibration, which can adapt and change its attenuation frequency range. …”
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674
Technologies Serving Concrete for Economy, Durability and Sustainability
Published 2020“…World population is increasing while resources are decreasing. Therefore, construction industry needs to find a way to produce more by consuming less. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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677
An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD and Disulfiram.
Published 2019“…From the molecular docking analysis with NAD , we observed that the interaction affinity of the NAD decreases with the impact of E504K variant. …”
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Finite element study of functionally graded porous femoral stems incorporating body-centered cubic structure
Published 2019“…Three levels of porosities (20%, 50%, and 80%) were modeled in HGP and FGP stems. …”
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680