RNA interference-mediated decrease in Ixofin3D results in decreased <i>B. burgdorferi</i> burden in the salivary glands and in murine skin. by Sukanya Narasimhan (73432)

B2 decreases glycolytic intermediates in cells. by Craig Eyster (392633)

“…The box indicates the clustering of decreased downstream glycolytic intermediates in B2-treated cells. …”

Ndel1 decreases oligomerization of Dyn2. by Mathieu Chansard (232234)

Interference with SUMOylation decreases FOXL2 transactivation. by Adrien Georges (201474)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Genes associated with androgen-induced decrease in H3K27me3 mark in the gene body and overlapping with promoters and distal enhancers involving long-range regulation of gene expres... by Sambit Roy (5463899)

“…C: Heatmap showing H3K27me3 peak counts in control and DHT-treated samples for 28 differentially expressed genes identified by comparing genes containing H3K27me3 peaks in the gene body with DEGs from the RNA-seq data. D: Average number of H3K27me3 peaks per 50bp overlapping with the promoter regions of 160 genes in the control samples and 55 genes in the DHT-treated samples. …”

Fumagillin treatment decreased MetAP-2. by Ke Zhang (115386)

Related to Fig 1. Enhancer deletion leads to decreased transcriptional levels with E2. by Luciana I. Gómez Acuña (18605719)

Subjects:

Decreased function of Nrf2 in the aging heart. by Sellamuthu S. Gounder (306106)

“…<p>(<b>A</b>) <b>Decreased nuclear translocation of Nrf2 is evident in the heart of aging mice.…”

Reducing MALAT1 expression decreased fibrosis of NIH-3T3 and decreased the expression level of P2ry2. by Mengjie Chen (483583)

Deformation of buried DN50 PE pipeline exposed to 5000 kN/m² stacking load with various buried depths. by Pengcheng Li (123281)

Normalized importance values (Mean Decrease Gini of Random Forest) of different category-wise features. by Md. Khaledur Rahman (4326274)

Basic form of 2D buildings. by Qindong Fan (11457629)

Decreased percentage of IFN-γ producing NKT cells in NK^-/-EM/IOE-mice. by Samar Habib (2616640)

Depletion of NK cells in NK^-/-EM/IOE mice decreased production of IFN-γ. by Samar Habib (2616640)

Depletion of NK cells in NK^-/-EM/IOE mice decreased production of iNOS and NO. by Samar Habib (2616640)

<i>In vitro</i> 95% CI lower and upper mean susceptibility responses of field isolates to antimalarials. by Winnie Okore (14139712)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…The antiproliferative activity of the novel <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. <i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…The antiproliferative activity of the novel <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. <i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

P2X7 is functionally expressed in the ovarian carcinoma cell line SKOV-3. by José David Nuñez-Ríos (18823719)