Loop C residues modulate activation through a complex network of interactions. by Ákos Nemecz (356830)

“…<p>Stick representation of the evaluated Arg, Asp, Glu, and Lys residues are labeled and color coded based upon effect, with Asp/Glu pink residues producing a strong decrease in pH₅₀ when mutated in combination, and yellow residues producing a nonsignificant or weak effect. …”

Differential expression patterns and functional gene groups associated with SARS-CoV-2 viral load across serially collected samples. by Vasanthi Avadhanula (259546)

Characterization of <i>L</i>. <i>monocytogenes</i> phage sensitivity, drop assay using wild-type Lm3-22 and <i>rliB</i> deficient Lm3-22-Δ<i>rliB</i>. by Yuan Tian (225002)

Illustration of p-value bias as a result of deflated standard errors. by Christiaan de Leeuw (457984)

“…The standard error deflation values are taken from the BMI analysis, with the large red point denoting the median and the other red points the 5^th, 25^th, 75^th and 95^th quantiles of their distribution (see Table <i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010921#pgen.1010921.t003" target="_blank">3</a></i>). …”

Table_1_Analysis of Breakthrough Reactions in 1,143 Desensitization Procedures in a Single Tertiary Hospital Using a One-Bag Desensitization Protocol.docx by Hyun Hwa Kim (12074039)

“…The use of steroid was also associated with lower occurrence of moderate to severe BTR (odds ratio 0.50, 95% CI 0.35–0.72, p < 0.001).</p>Conclusion<p>Most patients with HSRs to antineoplastic agents can safely receive chemotherapy through a one-bag desensitization protocol. …”

Table_2_Analysis of Breakthrough Reactions in 1,143 Desensitization Procedures in a Single Tertiary Hospital Using a One-Bag Desensitization Protocol.docx by Hyun Hwa Kim (12074039)

“…The use of steroid was also associated with lower occurrence of moderate to severe BTR (odds ratio 0.50, 95% CI 0.35–0.72, p < 0.001).</p>Conclusion<p>Most patients with HSRs to antineoplastic agents can safely receive chemotherapy through a one-bag desensitization protocol. …”

Table_3_Analysis of Breakthrough Reactions in 1,143 Desensitization Procedures in a Single Tertiary Hospital Using a One-Bag Desensitization Protocol.docx by Hyun Hwa Kim (12074039)

“…The use of steroid was also associated with lower occurrence of moderate to severe BTR (odds ratio 0.50, 95% CI 0.35–0.72, p < 0.001).</p>Conclusion<p>Most patients with HSRs to antineoplastic agents can safely receive chemotherapy through a one-bag desensitization protocol. …”

A Novel Nonsense Mutation in the <em>DMP1</em> Gene Identified by a Genome-Wide Association Study Is Responsible for Inherited Rickets in Corriedale Sheep by Xia Zhao (215170)

“…Previous outcross and backcross studies implicate inheritance as a simple autosomal recessive disorder. A genome wide association study was conducted using the Illumina OvineSNP50 BeadChip on 20 related sheep comprising 17 affected and 3 carriers. …”

Cyclin G2 is a target of calpain-mediated proteolysis. by Stefanie Bernaudo (4167634)

“…OV2008 cells were transiently transfected with the FLAG-CCNG2 plasmid and treated with or without 50μM calpeptin for 2h or 6h. Western blot analysis demonstrated a protective effect of calpeptin on cyclin G2 stability. …”

Immunohistochemical Staining of Human Breast Tissues for HtrA1. by Ning Wang (108353)

“…Panels CA-1 through CA-6 illustrate the decreased HtrA1 immunostaining in the DCIS components of invasive breast cancers (CA-1 through CA-4), and complete loss of HtrA1 immunostaining in invasive components of breast cancers (CA-5 and CA-6) which we characteristically observed. …”

Multiplex network of the VSTMBT and <i>nQ</i> example. by Avalon Campbell-Cousins (22110646)

Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx by Elisa Barbieri (115023)

“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”

Image1_CGX, a standardized herbal syrup, inhibits colon-liver metastasis by regulating the hepatic microenvironments in a splenic injection mouse model.DOCX by Sung-Bae Lee (6835907)

“…<p>Background: Colon-liver metastasis is observed in approximately 50% of patients with colorectal cancer and is a critical risk factor for a low survival rate. …”

Image1_CGX, a standardized herbal syrup, inhibits colon-liver metastasis by regulating the hepatic microenvironments in a splenic injection mouse model.tif by Sung-Bae Lee (6835907)

“…<p>Background: Colon-liver metastasis is observed in approximately 50% of patients with colorectal cancer and is a critical risk factor for a low survival rate. …”

[¹¹C]CHIBA-1001 as a Novel PET Ligand for α7 Nicotinic Receptors in the Brain: A PET Study in Conscious Monkeys by Kenji Hashimoto (36400)

“…Interestingly, the binding of [¹¹C]CHIBA-1001 in the frontal cortex of the monkey brain was significantly decreased by subchronic administration of the N-methyl-D-aspartate (NMDA) receptor antagonist phencyclidine (0.3 mg/kg, twice a day for 13 days); which is a non-human primate model of schizophrenia.…”

Supporting data for figures and tables. by Thamer Alghamdi (16406748)

“…</p><p>Conclusion</p><p>Our results point to ZLE as a promising hepatoprotective therapeutic tool in the treatment of schistosome hepatic fibrosis as it has anti-angiogenic, anti-proliferative, anti-fibrotic, and antioxidant effects in hamsters infected with <i>S</i>. …”

Table_1_Osteoporosis: a problem still faulty addressed by the Romanian healthcare system. Results of a questionnaire survey of people aged 40 years and over.pdf by Narcisa Jianu (19931601)

“…Moreover, participants already diagnosed with osteoporosis did not show a better disease knowledge than those without a diagnosis. …”

Table_1_Osteoporosis: a problem still faulty addressed by the Romanian healthcare system. Results of a questionnaire survey of people aged 40 years and over.pdf by Narcisa Jianu (19931601)

“…Moreover, participants already diagnosed with osteoporosis did not show a better disease knowledge than those without a diagnosis. …”

Smad3 is a direct target of miR-23b. by Xipeng Zhang (767297)

A simulation showing the effect of anti-PCSK9 antibodies therapy. by Yuri Efremov (11450672)

“…The binding of PCSK9 with antibodies prevents its binding with LDLR and leads to the decrease in LDL/VLDL levels. [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0264903#pone.0264903.ref018" target="_blank">18</a>].…”