Image_4_Pasteurella multocida Pm0442 Affects Virulence Gene Expression and Targets TLR2 to Induce Inflammatory Responses.TIF by Fang He (43884)

“…However, the mechanisms of infection are still poorly understood. Here, we found that Pm0442 was dramatically up-regulated in infected mice among 67 predicted lipoproteins of P. multocida serotype A CQ2 strain (PmCQ2). …”

Datasheet1_Efficacy and safety of sodium-glucose cotransporter-2 inhibitors for heart failure with mildly reduced or preserved ejection fraction: a systematic review and meta-analy... by Huzaifa Ahmad Cheema (13129113)

“…Aims<p>We sought to conduct a meta-analysis to evaluate the efficacy and safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in patients with heart failure (HF) with preserved ejection fraction (HFpEF) and HF with mildly reduced ejection fraction (HFmrEF).…”

Probability distributions of the hyperdegree in the HDPH model on a logarithmic scale with the different parameters. by Jian-Guo Liu (535164)

“…<p>(a) When  = 15, 50, and 150, the node number and the mean value are set as 10000 and 2, respectively. …”

Supplementary file 1_HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats.docx by Aishah Al-Jarallah (625579)

“…In isolated VSMCs, HDL attenuated Ang II-induced proliferation by reducing AT1R expression and decreasing Ang II-induced transactivation of EGFR. …”

Image 5_HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats.jpeg by Aishah Al-Jarallah (625579)

“…In isolated VSMCs, HDL attenuated Ang II-induced proliferation by reducing AT1R expression and decreasing Ang II-induced transactivation of EGFR. …”

Image 1_HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats.jpeg by Aishah Al-Jarallah (625579)

“…In isolated VSMCs, HDL attenuated Ang II-induced proliferation by reducing AT1R expression and decreasing Ang II-induced transactivation of EGFR. …”

Image 3_HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats.jpeg by Aishah Al-Jarallah (625579)

“…In isolated VSMCs, HDL attenuated Ang II-induced proliferation by reducing AT1R expression and decreasing Ang II-induced transactivation of EGFR. …”

Image 4_HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats.jpeg by Aishah Al-Jarallah (625579)

“…In isolated VSMCs, HDL attenuated Ang II-induced proliferation by reducing AT1R expression and decreasing Ang II-induced transactivation of EGFR. …”

Role of Type II Protein Arginine Methyltransferase 5 in the Regulation of Circadian <em>Per1</em> Gene by Jungtae Na (125603)

“…Molecular dissections have revealed that transcriptional feedback loops of the circadian clock genes drive the molecular oscillation, in which PER/CRY complexes inhibit the transcriptional activity of the CLOCK/BMAL1 heterodimer to constitute a negative feedback loop. In this study, we identified the type II protein arginine methyltransferase 5 (PRMT5) as an interacting molecule of CRY1. …”

Data_Sheet_1_Delayed Antiviral Immune Responses in Severe Acute Respiratory Syndrome Coronavirus Infected Pregnant Mice.pdf by Guohua Zhu (73670)

“…Here, we examined the differences in viral loads, SARS-CoV-2-specific antibody titers, proinflammatory cytokines, and levels of T cell activation after SARS-CoV-2 sub-lethal infection between pregnant and non-pregnant human Angiotensin-Converting Enzyme II (ACE2) transgenic mouse models. …”

Supplementary Material for: Effects of Dendritic Cell Subset Manipulation on Airway Allergy in a Mouse Model by Murakami R. (3223968)

“…<p><b><i>Background:</i></b> Two major distinct subsets of dendritic cells (DCs) are arranged to regulate immune responses: DEC-205+ DCs drive Th1 polarization and 33D1+ DCs establish Th2 dominancy. …”

Autophagic machinery is involved in cross-over endocytosis. by Nora Gehne (4357123)

“…Mean±SEM, for each group n>50. *p<0.05, **p<0.01, ***p<0.001; two-sided t test.…”

HL-IR is crucial for ticks to recognize cinnamaldehyde. by Ceyan Kuang (8554557)

“…The repellency rate decreased from 100%, 100%, 100% to 53.33%, 50%, 50% (****p < 0.0001). …”

Transcriptomics of Desiccation Tolerance in the Streptophyte Green Alga <i>Klebsormidium</i> Reveal a Land Plant-Like Defense Reaction by Andreas Holzinger (153856)

“…However, the effective quantum yield of Photosystem II and CO₂ fixation decreased sharply under the applied desiccation stress. …”

Pirt plays a role in mast cell-dependent itch. by Kush N. Patel (350598)

“…<p>(<b>A</b>, <b>B</b>) In an allergy model, ovalbumin (50 µg) induces less scratching in <i>Pirt^−/−</i> (n = 11) and SASH (n = 7) mice compared to WT controls (n = 8). …”

Image 2_One-year post lockdown trajectories of mental health and impact of COVID-19 lockdown-related factors.jpeg by Mathilde Mongeau (20864315)

“…</p>Methods<p>In this study, we examined longitudinal trajectories of mental health during the initial French lockdown period and up to one-year post-lockdown, among a representative sample of French adults aged over 50. …”

The Early Life History of the Clam <em>Macoma balthica</em> in a High CO₂ World by Carl Van Colen (119253)

Table 1_Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and... by Yaqi Yin (7280069)

“…Supplementation with folic acid plus vitamin B12 (SMD = −2.77, 95% CI [−3.23, −2.30], P < 0.0001) significantly reduced serum homocysteine levels and decreased the incidence of total complications (RR = 0.30, 95% CI [0.24, 0.38], P < 0.0001). …”

Data Sheet 1_ScRNA-seq combined with ATAC-seq analysis to explore the metabolic balance mechanism of CCl4-induced liver inflammatory injury.docx by Hui Liu (33624)

“…Transcription factor analysis found that Zhx2, a crucial suppressor of ETC, experienced sustained increases in chromatin accessibility within injured hepatocytes, but its expression level increased first and then decreased. …”

Congruent and incongruent stimuli for the numerical Stroop task. by Angela C. Rose (17636852)