PoreWalker output for the bovine aquaporin-1 water channel (1j4n). by Marialuisa Pellegrini-Calace (27075)

“…D, U and S indicate conical frustums of decreasing diameter, conical frustums of increasing diameter and cylinders, respectively; (C) pore diameter profile at 3Å steps corresponding the pore shape in (B). …”

Simulations on the response of protein denaturation temperature to changes in environmental temperatures under conditions of threshold selection for kinetic stability. by M. Luisa Romero-Romero (347004)

“…However, after 5000 simulation steps, the T_ENV value is increased to 90°C and, after 15000 simulation steps, it is decreased to 70°C. …”

HGP, gluconeogenesis (GNG), glycogenolysis (GLY) and GNG/HGP in short term fasting over 70 h. by Matthias König (156642)

“…(A) HGP decreases with increasing fasting time and reaches constant levels after around 25 h. …”

The effects of distributed delay on transcriptional signaling. by Krešimir Josić (155006)

“…<p>(A) For the simplified symmetric distribution where the delay takes values and with equal probability, the mean signaling time decreases with increasing variability in delay time, Eq. (8). …”

The Human Antiviral Factor TRIM11 Is under the Regulation of HIV-1 Vpr by Ting Yuan (293665)

“…In this study, we demonstrated that TRIM11 mainly suppressed the early steps of HIV-1 transduction, resulting in decreased reverse transcripts. …”

Numerical integration of the rate equations of the MerB reaction mechanism by Pedro Silva (532059)

“…</p> <p> </p> <p>Syntax is:</p> <p> </p> <p>HgMerB_kinetics [initial concentration of organomercurial (optional)] [number of steps with timestep tightening] [initial_timestep][pH] [type of molecule] [how many seconds of kinetic information you want] [HgMerB (or free MerB) concentration] [concentration of the Hg-removing molecules tested] [barriers in kcal.mol-1 for the 38 reaction steps] [name of output file]</p> <p> </p> <p>Type of molecule is : 1 for MerA, 2 for dithiothreitol, 3 for GSH or other monothiols</p> <p>Notes on the algorithm:</p> <p> </p> <p>A) concentrations are output whenever :</p> <p>A1) concentration of HgMerB decreases by 1%, or</p> <p>A2) concentration of product increases by 1% of initial MerB concentration, or</p> <p>A3) 10^7 integration timesteps have elapsed since the last output (or 3*10^5, if less than 10^7 integration timestpes have elapsed since the beginning of the simulation)</p> <p> </p> <p>B) Integration timestep is scaled to ensure that the concentration of every intermediate does not increase more than 10% of its previous concentration. …”

Quantitative phosphoproteomic analysis of the Sks1p signaling network in the filamentous Σ1278b genetic background. by Cole Johnson (222835)

“…<p>A) Schematic overview of major steps in the SILAC-based mass spectrometric analysis of Sks1p signaling; strain auxotrophies are indicated in the control and kinase-dead strains. …”

Dysregulation of immunological synapse formation during acute thymic atrophy. by Matthew J. Billard (227285)

“…Arrows may represent multiple steps. Plasma membranes are shown in gray. A detailed version of the original Metacore pathway is in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017940#pone.0017940.s006" target="_blank">Figure S6</a>. …”

The coevolution of effort and replication, replicated and corrected by Florian Kohrt (13918527)

“…At this point the decline of effort has made low-effort novel research more attractive than low-effort replications (because publishing a novel positive result is associated with a higher payof than publishing a replication) and consequently the replication rate decreases again. …”

The NC algorithm reconstructs random and most small-world network topologies in all three dynamical regimes. by Sinisa Pajevic (267425)

“…<p>(A) Comparison in reconstruction efficacy between the FC (left) and the NC algorithm (right; , 20% noise). is plotted against the number of propagation steps. …”

Quenching of FITC fluorescent lyophilisomes by trypan blue in the absence of cells. by Etienne van Bracht (654580)

“…<p>Results show decreased fluorescence (a) and efficient quenching (b) up to three washings steps of FITC fluorescent lyophilisomes by trypan blue.…”

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”^† by T. Santhosh Kumar (1903198)

“…The optimized synthetic route to the corresponding phosphoramidite building block of thymine proceeds in 4% overall yield over 15 steps from the starting diol. Crucial synthetic steps include (a) introduction of a C2-azido group prior to nucleobase coupling, (b) Vorbrüggen glycosylation primarily affording the desired α-anomer, (c) separation of α-l-<i>ribo</i>- and β-l-<i>ribo</i>-configured bicyclic nucleosides, and (d) selection of a suitable protecting group to avoid intramolecular Michael addition of the C2‘-amino group onto the C6-position. …”

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”^† by T. Santhosh Kumar (1903198)

“…The optimized synthetic route to the corresponding phosphoramidite building block of thymine proceeds in 4% overall yield over 15 steps from the starting diol. Crucial synthetic steps include (a) introduction of a C2-azido group prior to nucleobase coupling, (b) Vorbrüggen glycosylation primarily affording the desired α-anomer, (c) separation of α-l-<i>ribo</i>- and β-l-<i>ribo</i>-configured bicyclic nucleosides, and (d) selection of a suitable protecting group to avoid intramolecular Michael addition of the C2‘-amino group onto the C6-position. …”

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”^† by T. Santhosh Kumar (1903198)

“…The optimized synthetic route to the corresponding phosphoramidite building block of thymine proceeds in 4% overall yield over 15 steps from the starting diol. Crucial synthetic steps include (a) introduction of a C2-azido group prior to nucleobase coupling, (b) Vorbrüggen glycosylation primarily affording the desired α-anomer, (c) separation of α-l-<i>ribo</i>- and β-l-<i>ribo</i>-configured bicyclic nucleosides, and (d) selection of a suitable protecting group to avoid intramolecular Michael addition of the C2‘-amino group onto the C6-position. …”

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”^† by T. Santhosh Kumar (1903198)

“…The optimized synthetic route to the corresponding phosphoramidite building block of thymine proceeds in 4% overall yield over 15 steps from the starting diol. Crucial synthetic steps include (a) introduction of a C2-azido group prior to nucleobase coupling, (b) Vorbrüggen glycosylation primarily affording the desired α-anomer, (c) separation of α-l-<i>ribo</i>- and β-l-<i>ribo</i>-configured bicyclic nucleosides, and (d) selection of a suitable protecting group to avoid intramolecular Michael addition of the C2‘-amino group onto the C6-position. …”

Assembly at different time-scales. by Gui Araujo (22170819)

“…Composition of interaction types remains similar, but complexity decreases considerably as a result of a much lower connectance. …”

Data_Sheet_1_Explicit Sense of Agency in an Automatic Control Situation: Effects of Goal-Directed Action and the Gradual Emergence of Outcome.xlsx by Ryoichi Nakashima (539679)

“…Results showed that both characteristics decreased SoA in the manual control situation but increased SoA in the automatic control situation. …”

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”^† by T. Santhosh Kumar (1903198)

“…The optimized synthetic route to the corresponding phosphoramidite building block of thymine proceeds in 4% overall yield over 15 steps from the starting diol. Crucial synthetic steps include (a) introduction of a C2-azido group prior to nucleobase coupling, (b) Vorbrüggen glycosylation primarily affording the desired α-anomer, (c) separation of α-l-<i>ribo</i>- and β-l-<i>ribo</i>-configured bicyclic nucleosides, and (d) selection of a suitable protecting group to avoid intramolecular Michael addition of the C2‘-amino group onto the C6-position. …”

Force clamp procedure. by Mark C. Harris (3850867)

“…<p>Steps of a force clamp experiment are shown from left to right. …”

Distribution of relative overlaps between classifications. by Antonin Bergeaud (3955811)

“…<p>(Left) Distribution of overlaps at all time steps; (Right) Corresponding mean time-series. The decreasing trend starting around 1996 confirms a qualitative regime shift in that period.…”