Image1_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…However, it is not clear whether SGLT2 inhibitors have cardiovascular benefits in patients with cancer chemotherapy–related cardiac dysfunction. We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

Image4_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…However, it is not clear whether SGLT2 inhibitors have cardiovascular benefits in patients with cancer chemotherapy–related cardiac dysfunction. We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

Image2_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…However, it is not clear whether SGLT2 inhibitors have cardiovascular benefits in patients with cancer chemotherapy–related cardiac dysfunction. We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

Image5_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…However, it is not clear whether SGLT2 inhibitors have cardiovascular benefits in patients with cancer chemotherapy–related cardiac dysfunction. We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

DataSheet1_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy... by Changzhen Ren (10649432)

“…However, it is not clear whether SGLT2 inhibitors have cardiovascular benefits in patients with cancer chemotherapy–related cardiac dysfunction. We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

DataSheet_1_The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass.docx by Tuo Pan (9264234)

“…Secondly, a propensity-score matched cohort (sivelestat vs control: 50 vs 50) was performed in these 665 patients. …”

Image3_Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy.JPE... by Changzhen Ren (10649432)

“…However, it is not clear whether SGLT2 inhibitors have cardiovascular benefits in patients with cancer chemotherapy–related cardiac dysfunction. We aimed to determine whether empagliflozin (EMPA), an SGLT2 inhibitor, has a protective role against sunitinib (SNT)-induced cardiac dysfunction in a mouse model.…”

Circulating Tumor Cells Identify Early Recurrence in Patients with Non-Small Cell Lung Cancer Undergoing Radical Resection by Clara Bayarri-Lara (2512435)

“…</p><p>Results</p><p>51.8% of the patients evaluated were positive with the presence of CTCs at baseline. A decrease in the detection rate of CTCs was observed in these patients one month after surgery (32.1%) (p = 0.035). …”

DataSheet_2_IP-10 and MIG are sensitive markers of early virological response to HIV-1 integrase inhibitors.docx by Hortensia Álvarez (830316)

“…All of them matched their counterparts several months following ART initiation. MIG levels showed a greater decrease at day 10 in those treated with INSTI (p=0·038). …”

Metabolically healthy obesity and depressive symptoms: 16-year follow-up of the Gazel cohort study by Guy-Marino Hinnouho (3909874)

“…<div><p>Aims</p><p>The health correlates of the metabolically healthy obese (MHO) phenotype, particularly in relation to depressive symptoms remains unclear. Accordingly, we examined the risk of depressive symptoms in this phenotype using a 16-year follow-up prospective study.…”

Table_1_Implication of Non-electrostatic Contribution to Deionization in Flow-Electrode CDI: Case Study of Nitrate Removal From Contaminated Source Waters.DOCX by Jingke Song (526928)

“…Through periodic replacement of the electrolyte at a water recovery of 91.4%, we show that the FCDI system can achieve a continuous desalting performance with the effluent NO₃-N concentration below 1 mg NO₃-N L⁻¹ at low energy consumption (~0.5 kWh m⁻³) but high productivity.…”

DataSheet_1_IP-10 and MIG are sensitive markers of early virological response to HIV-1 integrase inhibitors.zip by Hortensia Álvarez (830316)

“…All of them matched their counterparts several months following ART initiation. MIG levels showed a greater decrease at day 10 in those treated with INSTI (p=0·038). …”

Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36 by Grace E. Cooper (3193272)

“…Concurrently, there was a significant increase in IFNβ gene expression in response to infection and we observed a significant decrease in bacterial phagocytosis (p = 0.031) and CD36 gene expression (p = 0.031) by MDM cultured for 24 h in 50IU/ml IFNβ. …”

Single-cell analysis reveals non-linear relationship between H3K27me3 and BCL6. by Ofir Griess (14761465)

“…BCL6 overexpression results in an increase in H3K27me3 as well as additional marks of heterochromatin, and a decrease in histone acetylation levels. <b>H.…”

Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from <i>Melaleuca styphelioides</i> on carbon tetrachloride-induced hepatotoxicity in HepG2 cel... by Eman Al-Sayed (2934060)

“…(Myrtaceae) showed a significant hepatoprotective effect in a CCl₄-induced toxicity model in mice. …”

Effects of MBHA3 treatment on the acidic compartments of T. cruzi. by Jana M. Sandes (548760)

“…Nevertheless, in cells treated with the 4x IC₅₀ of MBHA3, a striking decrease of the fluorescent signal from red channel was observed. …”

Comparison of urinary NGF/Cr and BDNF/Cr levels in clinical responders and non-responders after intravesical hyaluronic acid treatment in IC/BPS patients. by Yuan-Hong Jiang (398786)

“…</p>$<p>Responder in FBC: increase of ≥ 50% of baseline.</p><p>Data are expressed as mean ± standard deviation.…”

Expression of the ETS-5 target gene <i>gcy-9</i> restores CO₂-chemosensitivity to <i>ets-5</i> mutants. by Julia P. Brandt (176082)

“…Wild-type URX neurons (top panel) showed a small decrease in the ratio of YFP:CFP emissions in response to 10 s CO₂ pulses indicating decreases in cell calcium. …”

Absence of capsule at the division septum results in increased exposure of bacteria cell wall and susceptibility to lysis. by Joana Figueiredo (176254)

“…B) Quantification of cell bound LytA-GFP fluorescence. Bacteria were grouped in three different classes (n> 50), depending on their cell cycle stage: (I) recently divided cells; (II) cells initiating division as seen from invagination of cell surface; (III) cells at the final steps of division, with deep invagination at division septum. …”

Image_1_Optimizing estradiol level for gonadotrophin-releasing hormone antagonist initiation among patients with simple tubal factor infertility.jpg by Yizhuo Wang (5132726)