Example time-course plots derived from the primary screen, followed to the right by the corresponding concentration-response curves. by Anton Simeonov (85099)

“…<p>(A, B) Non-fluorescent inhibitors, compounds 3 and 14; the decrease in fluorescence is inhibited at increasing compound concentrations while the starting fluorescence remains constant. …”

Expression of Liprin-α4 in RNAi lines. by Kathrin Kiok (210915)

“…<p>The control pSUPER contains the vector without the RNAi construct and knock-down lines contain the vector including the siRNA construct against Liprin-α4. (A) Liprin-α4 is 50% down regulated in 323 and it is decreased approximately 20% in RNAi line 847. …”

Spermatogonial germ cell proliferation in prepubescent males. by J. Kim Holloway (218875)

“…Arrowheads mark mitotic TUNEL-positive cells. Scale bar is 50 µm. Quantitation of the GCNA-1 labeled (M) and TUNEL-positive (N) cells reveals a statistically significant decrease in prospermatogonia, accompanied by an increase in apoptotic cells (asterisks).…”

Annealing temperature optimization of the primer droplet library. by Alexander Herrmann (20166)

“…Increasing the annealing temperature to 58°C only results in a decrease in amplicon yield.</p>…”

Effects of CTP on CoaE enzymatic activity. by Guneet Walia (258006)

“…<p>(A), Histogram depicting the percent decrease in CoaE activity in the presence of CTP, with the activity of CoaE in the presence of ATP (1 mM) and DCoA (0.5 mM) treated as 100% (Lane 1). …”

Binarized cross recurrence plot of the PCn-M1 functional connectivity. by Clara Rodriguez-Sabate (4512394)

“…The control group shows a high-density ON-ON match at the beginning (0–40 sec) of the resting-task block (Fig 6A), and between the 50–160 sec of the motor-task block (Fig 6C). …”

Cell cycle analysis. by Shuai Wu (401994)

“…<p>Cell cycle analyses were performed after T24 cells were treated with hWJMSC-MVs (0, 50, 100 and 200 µg/ml protein) for 48h. Compared to T24 cells alone (A), hWJMSC-MVs induced a significant increase of T24 cells in G₀/G₁ phase and a dramatic decrease in S phase (B, C, D, p<0.01). …”

Binarized cross recurrence plot of the MT-M1 functional connectivity. by Clara Rodriguez-Sabate (4512394)

“…The control group shows a high-density ON-ON match at the beginning (0–40 sec) of the resting-task block (Fig 5A), and between the 50–160 sec of the motor-task block (Fig 5C). …”

At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes-2 by Costas Papatheodoropoulos (78587)

“…Note the great value dispersion of instant period during drug application at ≥50 μM. Data in "a" and "b" were obtained from two different slices. …”

Aspirin treatment induces activated T cell death <i>in vitro</i>, promotes osteogenesis of BMMSCs, and improves BMD in OVX mice. by Takayoshi Yamaza (67506)

“…(C) On the other hand, T cells activated by cultured on CD3εΑb-coated dishes showed decreased viability in 50 µg/ml ASP-treated group, but not in 2.5 µg/ml ASP-treated group. …”

Table_2_An approach to uncover the relationship between 17b-estradiol and ESR1/ESR2 ratio in the regulation of canine corpus luteum.xlsx by Antenor Pereira Bonfim Neto (13186410)

“…Nevertheless, we are still missing a better comprehension of E2 functions in the canine CL, especially regarding the specific roles of estrogen receptor alpha (ERa) and ERb, encoded by ESR1 and 2, respectively. …”

Table_1_An approach to uncover the relationship between 17b-estradiol and ESR1/ESR2 ratio in the regulation of canine corpus luteum.xlsx by Antenor Pereira Bonfim Neto (13186410)

“…Nevertheless, we are still missing a better comprehension of E2 functions in the canine CL, especially regarding the specific roles of estrogen receptor alpha (ERa) and ERb, encoded by ESR1 and 2, respectively. …”

Table_3_An approach to uncover the relationship between 17b-estradiol and ESR1/ESR2 ratio in the regulation of canine corpus luteum.xlsx by Antenor Pereira Bonfim Neto (13186410)

“…Nevertheless, we are still missing a better comprehension of E2 functions in the canine CL, especially regarding the specific roles of estrogen receptor alpha (ERa) and ERb, encoded by ESR1 and 2, respectively. …”

Simulations Demonstrating the Effects of Varying the Degree of Resistance on Treatment Success Rates by Marcel E Curlin (32388)

“…<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g005" target="_blank">Figures 5</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g006" target="_blank">6</a>, (A) and (C) demonstrate success rates as the duration of induction therapy is increased, and (B) and (D) demonstrate success rates over a range of induction therapy/therapy intensification start times. …”

Data_Sheet_2_Determination of factors associated with serum cholesterol response to dairy fat consumption in overweight adults: Secondary analysis from an RCT.docx by Aileen O'Connor (13191693)

“…A 6-week randomized parallel intervention trial was carried out in healthy volunteers (≥50 years, BMI ≥25 kg/m²). …”

Data_Sheet_1_Determination of factors associated with serum cholesterol response to dairy fat consumption in overweight adults: Secondary analysis from an RCT.docx by Aileen O'Connor (13191693)

“…A 6-week randomized parallel intervention trial was carried out in healthy volunteers (≥50 years, BMI ≥25 kg/m²). …”

Oxidative modification of Homer results in loss of solubility. by Igor Nepliouev (341769)

“…Cells were lysed in buffer containing 1% Triton, 8 M guanidine HCL, and 50 mM TCEP. Analysis of whole lysates showed a decrease in detectable Homer over time.…”

Resting energy expenditure adaptation after short-term caloric restriction in morbidly obese women by Andresa Toledo TRIFFONI-MELO (10470338)

“…Therefore, short-term caloric restriction in morbidly obese women led to a decrease in resting energy expenditure and fat-free mass, which suggests a rapid adaptation of energy expenditure.…”

SRPK79D overexpression disrupts synaptic Brp and impairs synapse function. by Ervin L. Johnson III (259396)

“…(G) Quantification of average EPSP amplitude and quantal content (QC) in SRPK79D-RD*-overexpressing larvae show a greater than 50% decreases in both measures relative to control. …”

Factors associated with morphometric brain changes in cognitively normal aging by Renata Eloah de Lucena Ferretti-Rebustini (6117596)

“…METHODS: A cross-sectional study of 414 subjects, ≥50 years old submitted to clinical assessment and brain autopsy, after informed consent, was carried out at the São Paulo Autopsy Service, Brazil. …”