Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

“…We report the synthesis and characterization of 14 complexes of the type (Au(R)[N̂N])⁺, where R = tunable biaryldialkyl phosphine ligands and [N̂N] = bidentate phenanthroline derivatives as anticancer agents. …”

Density increases cadherin-11 and GSK3β inhibitors decrease cadherin-11 expression. by Anne K. Farina (266373)

Definitions of the features selected [50]. by Yu Zhang (12946)

PAT inhibitor decreased BMP2-induced osteoblast differentiation, which was likely mediated by Osx. by Wai Fook Leong (375133)

Disruption of PKA anchoring, as caused by Ht31 peptide, decreases PKA phosphorylation of downstream targets. by Rodrigo F. Oliveira (184716)

“…<p>When adenylate cyclase (AC) is in the spine, disruption of PKA anchoring reduces by 30% both phosphoThr34 DARPP-32 (p = 0.0006) and phosphoSer845 GluA1 (p = 0.0036). When adenylate cyclase is in the dendrite, disruption of PKA anchoring produces a significant decrease in phosphoThr34 DARPP-32 (p = 0.0005), but not phosphoSer845 GluA1 (p = 0.16). …”

IκBαM.1-Infected Mice Have Decreased Latency in Lung B Cells 16 dpi after Intranasal Infection by Laurie T Krug (68237)

Silencing of Doublecortin-Like (DCL) Results in Decreased Mitochondrial Activity and Delayed Neuroblastoma Tumor Growth by Carla S. Verissimo (463419)

Reduced ACh-induced vasorelaxation due to decreased SK3 channel contribution in ovx vessels. by Fui C. Yap (611989)

Pestones A and B from a Fungus <i>Pestalotiopsis</i> sp. Bound to Mutant p53 and Changed Its Conformation by Yusaku Sadahiro (8725830)

“…Compound <b>1</b> was found to induce apoptosis in Saos-2 (p53^R175H) cells by flow cytometry analysis and decreased tumor growth <i>in vivo</i> using a mouse model with HuCCT1 (p53^R175H) cells.…”

Imatinib induces the differentiation of human normal erythroblasts and decreases cell surface expression of c-Kit. by Diane D'allard (405441)

DJ-1 gene deletion decreases mitochondrial respiratory chain function in dopaminergic neuronal cells. by Jun Young Heo (179572)

Unaltered energy expenditure and decreased physical activity in chow-fed mice with adult-onset hypothalamus-specific Y1Y5 receptor deletion. by Amy D. Nguyen (153830)

CaMKII inhibition does not alter dendritic spine density, but decreases dendritic length and complexity. by Jason R. Klug (132807)

Ang II decreases brain hemorrhages, delays experimental cerebral malaria and increases survival of mice. by Julio Gallego-Delgado (796586)

Abolishing the ordered neuron density gradient decreased the positive correlation observed for axon elongation scaling. by Sarah F. Beul (6008801)

Competition localization increases with growth rate or the distances between colonies, and decreases with the resource diffusion constant. by Jeremy M. Chacón (8259792)

Trial Sequential Analysis, parallel group trials, decreased appetite, nausea, vomiting, and abdominal pain. by Mathilde Holmskov (4112062)

Secreted Human Adipose Leptin Decreases Mitochondrial Respiration in HCT116 Colon Cancer Cells by Einav Yehuda-Shnaidman (461266)

“…Our results show that conditioned media from obese (vs. non-obese) subjects decreased basal (40%, <i>p<0.05</i>) and maximal (50%, <i>p<0.05</i>) OCR and gene expression of mitochondrial proteins and Bax without affecting cell viability or expression of glycolytic enzymes. …”

Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis. by William R. Swindell (175427)

“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log₂-transformed fold-change less than -0.50). …”

The treatment with anti-CXCR3 decreases the number of CD8⁺ T cells in the heart. by Camila Pontes Ferreira (6194006)