Sorting of VAMPs 4 and 7. by Daniela A. Sahlender (201771)

“…<p>a, Schematic diagrams of the wild-type and mutant constructs. b, Alignment of the SNARE domains of the five VAMPs. …”

Table5_Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone.XLSX by Hagar A. Morgaan (15350347)

“…</p><p>Methods: PE was induced by oral administration of L-NAME (50 mg/kg/day) for the last 7 days of pregnancy. …”

Table 1_Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreatio... by Dawna Salter (18498396)

“…This pilot study evaluated the efficacy of a standardized B. serrata extract LI51202F1 (SBS) to decrease soreness and improve recovery after repeated bouts of downhill running (DHR) compared to placebo (PLA). …”

Image2_First-in-Human, Double-Blind, Randomized, Placebo-Controlled Trial of TQ-F3083, a New Dipeptidyl Peptidase-4 Inhibitor, in Healthy Chinese Adults.TIF by Jingrui Liu (1694983)

“…The accumulation factor was 1.39 after multiple dose for 7 days. Decreased plasma exposure (84.87% decrease in C_max, 49.23% in AUC_0-t, and 47.77% in AUC_0-∞) was observed with administration after a high-fat and high-calorie standardized breakfast. …”

Image1_First-in-Human, Double-Blind, Randomized, Placebo-Controlled Trial of TQ-F3083, a New Dipeptidyl Peptidase-4 Inhibitor, in Healthy Chinese Adults.TIF by Jingrui Liu (1694983)

“…The accumulation factor was 1.39 after multiple dose for 7 days. Decreased plasma exposure (84.87% decrease in C_max, 49.23% in AUC_0-t, and 47.77% in AUC_0-∞) was observed with administration after a high-fat and high-calorie standardized breakfast. …”

Table 2_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). Among the five Sociodemographic Index (SDI) regions, the highest EAPCs were observed in the high SDI regions for incidence (−1.63%; 95% CI, −1.74 to −1.52), mortality (−1.79%; 95% CI, −2.01 to −1.58), and DALYs (−1.67%; 95% UI, −1.84 to −1.50). …”

Image3_First-in-Human, Double-Blind, Randomized, Placebo-Controlled Trial of TQ-F3083, a New Dipeptidyl Peptidase-4 Inhibitor, in Healthy Chinese Adults.TIF by Jingrui Liu (1694983)

“…The accumulation factor was 1.39 after multiple dose for 7 days. Decreased plasma exposure (84.87% decrease in C_max, 49.23% in AUC_0-t, and 47.77% in AUC_0-∞) was observed with administration after a high-fat and high-calorie standardized breakfast. …”

Table 1_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). Among the five Sociodemographic Index (SDI) regions, the highest EAPCs were observed in the high SDI regions for incidence (−1.63%; 95% CI, −1.74 to −1.52), mortality (−1.79%; 95% CI, −2.01 to −1.58), and DALYs (−1.67%; 95% UI, −1.84 to −1.50). …”

Dissociation between skin test reactivity and anti-aeroallergen IgE: Determinants among urban Brazilian children by Neuza M. Alcantara-Neves (253713)

Growth factors expression and ultrastructural morphology after application of low-level laser and natural latex protein on a sciatic nerve crush-type injury by Fernando José Dias (3174455)

MiR-150 expression promotes myeloid differentiation of CD34+ PBMCs from healthy donors. by Valerie A. Morris (462679)

“…<p>Primary CD34+ PBMCs were transduced with pre-miR-150 or empty control lentiviral (ECV) supernatants, sorted for GFP expression, and then assayed by flow cytometry for CD11b, CD34, and CD14 expression or colony formation by colony-forming unit (CFU) assays. (A) Cells were assessed by flow cytometry at the indicated days after cell transduction cultured in the presence of rhSCF, rhIL3, rhIL6, rhGCSF, rhGMCSF (50 ng/ml each), and EPO (2 U/ml). …”

Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic... by Alexandre Champroux (18547075)

“…Thus, suppression of this miRNA amplification system when sperm miR-34c levels are reduced in CSI stressed mice can explain how a comparable fold-suppression of miR-34/449 levels can be found in PIEs derived from them, despite sperm containing ~50-fold lower levels of these miRNAs than those already present in PIEs. …”

Inhibition of collagen and fibronectin expression by roscovitine in SSc and in normal fibroblasts. by Richard A. Steinman (117481)

“…Cells treated for 23 hours with DMSO vehicle (D), 6.25 µg/mL roscovitine (R), 10 ng/mL TGF-β (T), or 50 ng/mL IL-6 (6). PARP band at 116 kD is also shown; no 89 kD cleaved PARP band (a marker of apoptosis) was detected. …”

Image1_Development, Optimization and Evaluation of 2-Methoxy-Estradiol Loaded Nanocarrier for Prostate Cancer.pdf by Nabil A. Alhakamy (1963378)

“…<p>The therapeutic efficacy of antineoplastic agents possessing a selective target to the nucleus of the cancer cells could be enhanced through novel formulation approaches. …”

miR-223 null macrophages have enhanced inflammatory signaling and increased FBXW7 levels. by Jeffrey A. Deiuliis (3331071)

“…(C) Immunoblot data examining response of primary macrophages from WT and miR-223 knockout mice (KO) to LPS and combined IFNγ/LPS; 50μg of whole cell lysate was loaded per lane and run on a denaturing SDS PAGE gel. …”

AdV-ZFP-VEGF significantly reduces mechanical and thermal allodynia at 8 weeks post-SCI. by Sarah A. Figley (389639)

“…(C) Below-level thermal allodynia. A 50°C thermal stimulus was applied to the distal tip of the tail. …”

Effects of the particle of ground alfalfa hay on the growth performance, methane production and archaeal populations of rabbits by Siqiang Liu (5754062)

Factors associated with people in the community not having sought care for TB symptoms (Gap 1). by Tulip A. Jhaveri (18625800)

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…Here, we report the in vitro and in vivo characterization of the anti-inflammatory effects of CHF6297, a novel potent and selective p38α inhibitor designed for inhalation delivery as a dry powder formulation. …”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…Here, we report the in vitro and in vivo characterization of the anti-inflammatory effects of CHF6297, a novel potent and selective p38α inhibitor designed for inhalation delivery as a dry powder formulation. …”