First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

Subjects:

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

Subjects:

Increased lipid accumulation and decreased klotho expressions in palmitate-treated mouse podocytes. by Jeong Suk Kang (7359572)

“…(d) ELISA assay demonstrating decreased soluble klotho by palmitate treatment. Culture media was collected from podocytes treated by palmitate in a dose-dependent manner. …”

FTY720 decreases cerebral lymphocyte invasion. by Arthur Liesz (349478)

Riociguat decreases hyperoxia-induced vascular remodeling. by Keyur Donda (5497400)

“…<p>(<b>A</b>, <b>C</b>) Double immunofluorescence staining for vWF (green signal) and α-SMA (red signal) plus DAPI nuclear stain (blue signal). …”

AMPK activation is decreased with aging in human skin. by Yasuo Ido (172159)

H2-K^b overexpression decreases NSPC proliferation and impairs adult hippocampal neurogenesis. by Karin Lin (11037548)

Sphere-forming efficiency decreases following radiation. by Vicky T. Nguyen (5029244)

VHFD becomes dehydrated, decreasing its palatability. by Joshua Cordeira (17002146)

“…(B) Mass lost correlated with VHFD preference. (C) Dehydrating VHFD decreased preference to consume it. …”

Tau aggregation decreased in mixed isoform reactions. by Stephanie J. Adams (364585)

Demonstration of the effects of decreased size at metamorphosis on amphibians by Tyrone B. Hayes (29098)

Cellular co-infection decreases the potential for superinfection. by Brigitte E. Martin (8366847)

Supplementary Material for: Cardiac Troponin Is Elevated in Patients with Thyrotoxicosis and Decreases as Thyroid Function Improves and Brain Natriuretic Peptide Levels Decrease by Watanabe N. (4118812)

“…At baseline, median hsTnI was 1.9 pg/mL and ranged from 0 to 69.6 pg/mL. Five patients (3.5%) had a high hsTnI value that exceeded 26.2 pg/mL, which is used as the cutoff for diagnosis of myocardial infarction, and 22 patients (15.4%) had an intermediate value between 5.0 and 26.2 pg/mL. …”

Injection of rIL-6 in IL-6KO mice decreased chronic disease severity following CB3/LPS treatment. by Maya C. Poffenberger (262165)

“…Magnification:400×. (B) Chronic cardiac disease histology was scored blindly by a four tier grading system to determine severity differences: grade 1, 0–10% pathology; grade 2, 11–25%; grade 3, 26–50%; grade 4, greater than 50% (black circles indicate wt mice with DMEM, white circles indicate IL-6KO mice with DMEM, grey circles indicate IL-6KO mice with rIL-6) (bar is mean±SE, *p<0.05). …”

Elevated Ang2 expression and decreased Ang1 expression during <i>O</i>. <i>tsutsugamushi</i> infection. by Brandon Trent (8520288)

Knockdown of S1PR2 significantly decreased IL-1b, IL-6, and TNF-a protein expressions induced by <i>A</i>. <i>actinomycetemcomitans</i> (<i>Aa</i>) in BMMs. by Hong Yu (6528)

T198A/G substitution markedly decrease p27 protein stability. by Monica Schiappacassi (227672)

In the null model the event rate does not decrease as a function of the inverse of time. by Thomas O. Richardson (251876)

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…The number of PV-positive cells was quantified in high magnification images. <b>F</b>. Example image of a biocytin-labeled PFC PV interneuron from a control mouse (left) and from cuprizone-treated mouse (right); scale bar: 50 µm. …”

Immunization for EAE decreased the counts of CD4+ and CD8+ T-PBLs in DA rats. by Mirjana Nacka-Aleksić (3342095)