A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

“…To date, several autotaxin/ENPP2 inhibitors have been reported; however, none were able to completely and continuously inhibit autotaxin/ENPP2 <i>in vivo</i>. In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”

Effect of <i>slc43a3</i> deletion on physical activity of male and female WT and KO mice. by Aaron L. Sayler (19797446)

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Cdk5 siRNA knockdown decreased Cdk5 activity, diminished WT1 expression and viable cell numbers, and increased cleaved caspase 3 level. by Ya-Li Zheng (454837)

“…Cdk5 siRNA induced cleaved caspase 3 expression (upper panel, lane 2; bar 2 vs bar 1, p<0.05). E. Western blotting analysis showed a decline of WT1 expression in Cdk5 siRNA podocytes (upper panel, lane 2). …”

The percent of students who, if a science instructor were to tell a joke about a specific subject, might find the joke funny and might find the joke offensive. by Katelyn M. Cooper (5634851)

Analysis the pigment contents and net photosynthetic rate of NIP, <i>hdy1</i> and transgenic lines. by Juan Zhao (109151)

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Expression levels of OsFdC2 in NIP, <i>hdy1</i> and transgenic lines. by Juan Zhao (109151)

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Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ul... by Othmar Moser (789838)

“…</p><p>Results</p><p>BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. …”

IC₅₀ of indole alkaloid against lipase [23]. by Atikarn Janthongkaw (17020498)

Increased body weight and decreased expansion of pro-inflammatory CD4+ T-cells from blood in Tg-HD5 rats. by Osiris Marroquin Belaunzaran (224031)

Decreased neutrophil levels in HIF^C mice correlates to decreased production of CXCL1 and not migration defects. by Kelly M. Shepardson (404375)

Anesthetics differentially decrease cilia-driven particle transport speed (PTS). by Ghulam Murtaza (2559319)

DNA concentrations of ucfDNA across WT, <i>Dnase1l3</i>^-/- and <i>Dnase1</i>^<i>-/-</i> mice with quantifiable ucfDNA using Qubit assay. by Meihui Chen (1670020)

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

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Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

“…In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM). …”

Meta-analysis heatmap of Slfn3KO males vs. WT males compared to Slfn3KO females vs. WT females. by Emilie E. Vomhof-DeKrey (6900677)

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Lists the 80 genes decreased in Ercc1 Δ/- vs. WT under normoxia (21%) with absolute value of the log2-Fold Change >1.25 and adjusted <i>p</i>-value <0.01. by Robert S. Rogers (15852564)

“…<p>Lists the 80 genes decreased in Ercc1 Δ/- vs. WT under normoxia (21%) with absolute value of the log2-Fold Change >1.25 and adjusted <i>p</i>-value <0.01.…”

Analysis the pigment contents, net photosynthetic rate and Fe contents in the leaves of NIP and <i>hdy1</i>. by Juan Zhao (109151)

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Summary of structural dynamics of WT and mutant RhoGAPs-RhoA complexes. by Zen Kouchi (14898435)

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Table_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.DOCX by Kai Yang (73590)

Image_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.TIF by Kai Yang (73590)