Evaluation of Local Performance and Global Tolerance for the NADPH redox cycle in human erythrocytes with the B-form (normal) of G6PD. by Pedro M. B. M. Coelho (240895)

“…<p>§The criteria were listed under the sub-section “Criteria for Functional Effectiveness” of the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013031#s2" target="_blank">Methods</a> Section;</p><p>|To improve performance, one must have either a high () or a low () value for the associated criterion;</p><p>†The quantitative value was determined by using the data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013031#pone-0013031-t001" target="_blank"><b>Table 1</b></a> and the analytical expressions listed in <b>Table S1, S2</b> of the <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013031#pone.0013031.s001" target="_blank">Text S1</a></b>;</p><p>‡The optimum value was determined analytically except for criterion 7 which had to be determined numerically;</p><p>*[T represents tolerance to a fold decrease and T] represents tolerance to a fold increase.…”

GAP-promoted deactivation of G_q after removal of receptor. by Marc Turcotte (53469)

“…<p>Left inset: Segment of <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000148#pcbi-1000148-g006" target="_blank">Figure 6</a> (cytosolic nucleotide concentrations) showing the results of a search of R-A space for pairs of high and low GAP concentrations where a 500-fold increase in GAP concentration caused less than 15% decrease of <i>Z</i> at steady-state but caused at least a 2-fold increase in the rate of deactivation when the concentration of receptor was instantaneously set to zero (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000148#s4" target="_blank">Materials and Methods</a>). …”

Image_1_Interleukin 23 Produced by Hepatic Monocyte-Derived Macrophages Is Essential for the Development of Murine Primary Biliary Cholangitis.jpeg by Debby Reuveni (5633135)

<i>ACVR2</i> promoter hypermethylation and LOH in colon cancer specimens and the MSS HT29 cell line and correlation of <i>ACVR2</i> promoter hypermethylation and loss of <i>ACVR2</... by Barbara Jung (155690)

“…<p>A) ACVR2 promoter with map of positioning of MSP primers B) Using a CpG islands search program, we identified the CpG islands within the <i>ACVR2</i> promoter based upon following stringent criteria: ∼CG percentage>55%; observed CpG/expected CpG >0.65; length >500 bp. …”

Table_1_The safe lowest effective power of subthreshold micropulse laser treatment in Chinese patients with acute or chronic central serous chorioretinopathy.DOCX by Ting Xie (191025)

“…We found that the lowest effective laser power for acute CSC was 425 mW (−225.50 μm vs. −171.24 μm vs. −114.50 μm vs. −130.54 μm vs. −68.00 μm, p < 0.001), showing a significant CMT reduction at this power, but no significant increase in BCVA (−0.15 ± 0.10 logMAR vs. −0.20 ± 0.16 logMAR vs. −0.14 ± 0.11 logMAR vs. −0.17 ± 0.30 logMAR vs. −0.11 ± 0.14 logMAR, p > 0.05). …”

Comparison of qualitative experimental input–output relations and model predictions. by Linda Irons (9292686)

“…Model predicted absolute differences in steady state species activity when the inputs (intramural stress, wall shear stress (Wss), and AngII) are perturbed relative to baseline: orange denotes an increase and blue a decrease relative to the original steady state (white). …”

Discrimination of differentially expressed proteins in six gels. by Sivagnanam Ananthi (104589)

“…<p>The histograms were generated by DeCyder DIA software, plotting spot frequency (left y-axis) against log volume ratio (x-axis), and a normal distribution model (red line) was fitted to the main peak of the frequency histogram. A 2 fold variation in expression level was set as threshold. …”

Table_1_Impact of 12-Week Moderate-Intensity Aerobic Training on Inflammasome Complex Activation in Elderly Women.PDF by Marta Gomarasca (12117015)

“…NLRP3 and TLR4 levels were reduced 2 folds between T1-pre and T2-pre and induced at T2-post, compared to T2-pre, by 2.6- and 2.9-fold, respectively. …”

Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes by Zhaoyun Jiang (15317737)

“…We assessed genomic alterations using a 23-gene panel, which includes most of the HR-related genes and DNA mismatch repair (MMR) gene, through next-generation sequencing. …”

Characterization of Tzb-refractory <i>HER2</i>-gene Amplified SKBR3 Breast Cancer Cells. by Alejandro Vazquez-Martin (75018)

“…Treatment with Tzb concentrations as high as 100 µg/mL Tzb failed to significantly decrease cell viability in TzbR POOLs whereas a 10 times lower concentration of Tzb drastically reduced cell viability (>50%) in SKBR3 parental cells. …”

Difference between cystatin C- and creatinine-based estimated glomerular filtration rate and incident hypertension and the mediating role of Triglyceride Glucose Index by Zixuan Zhang (6957035)

“…During a mean follow-up period of 5.0 years, 613 new cases of hypertension occurred. …”

Impact of astrocyte depletion upon non-basement membrane extracellular matrix (ECM) components. by Lisa Allnoch (10583549)

“…Immunohistochemistry detecting decorin showed a significant decrease of decorin positive area in astrocyte depleted animals compared to their controls (<b>F</b>). …”

Loss of MYRF leads to early retinal degeneration in mice. by Sarah J. Garnai (6658520)

“…(G) Quantitative analysis of cone fraction compared to fraction of total retinal cells. There is a significant decrease in IS/OS area and cone fraction in <i>RxCre;Myrf</i>^<i>fl/fl</i> retinas. n = 8 eyes, 6 animals (control); n = 6 eyes, 3 animals (<i>RxCre;Myrf</i>^<i>+/fl</i>), n = 4 eyes, 4 animals (<i>RxCre;Myrf</i>^<i>fl/fl</i>). …”

Somatic <i>HTT</i> CAG instability differs between B6.<i>Hdh^Q111</i>^/+ and 129.<i>Hdh^Q111</i>^/+ mice. by Ricardo Mouro Pinto (207712)

Layer-specific quantification of RS and FS neuronal activity in wM2 across learning. by Vahid Esmaeili (12700352)

“…Left: baseline-subtracted (50 ms prior to whisker onset) population firing rate (mean ± SEM) for different cortical layers (L2/3, L5, and L6a) overlaid for Novice mice (244 neurons in 7 mice) and Expert mice (401 neurons in 11 mice). …”

Steel slag-based silicate fertilizer suppresses grain cracking in brewer’s rice cultivar “Yamada-Nishiki” by Youshi Tazoe (20410017)

“…In addition, when the harvested rice was air-dried at 50°C in a ventilated dryer, the rate of decrease in the moisture content of unhulled rice was slower in the silicate treatment and the ratio of cracked grains of silicate-applied rice was also lower. …”

Building leakage, temperature, and relative humidity. by Mytien Nguyen (3877090)

“…<p><b>A</b>) Decrease in building leakage (dark blue; left y-axis) and decrease in air changes <i>per</i> h at 50 pascal depressurizations (ACH₅₀) (light blue; right y-axis) for each case home are shown as negative numbers. …”

Immobilization of Burkholderia cepacia on Pristine or Functionalized Multi-Walled Carbon Nanotubes and Application on Enzymatic Resolution of (RS)-1-Phenylethanol by Michele R. G. Dias (5668394)

“…For the functionalization, three treatments were used, these being in H2SO4/HNO3 (acid, MWCNTs-A), KOH (basic, MWCNTs-B) or in H2O2 (oxidizing agent, MWCNTs-O). …”

Cytoprotective effect of cooling against chemotherapy drug-mediated toxicity in hair follicle-derived keratinocytes and flow cytometry-based quantification of cellular doxorubicin... by Christopher Dunnill (9525217)

“…The image is an overlay of the log₁₀ median fluorescence intensity (MFI) histograms associated with each dose of doxorubicin, as indicated. d) MFI values for independent replicate experiments (n = 3) performed as in (c) were plotted against the respective doxorubicin concentration ([drug]) with the resulting equation from linear regression analysis included on the graph together with the R² value. e) The uptake of doxorubicin by ORSK cells at normal (37°C) and cooling conditions (22 and 18°C) was determined by flow cytometry, before linear regression analysis was performed and fold decrease in drug uptake was calculated as explained in detail in the main text. …”

AltAnalyze functional predictions for confirmed CP differentiation AS events. by Nathan Salomonis (1526)

“…Negative SI fold changes indicate increased alternative exon expression in CPs and vise versa. …”