Showing 11,841 - 11,860 results of 67,367 for search '(( 50 ((((we decrease) OR (mean decrease))) OR (a decrease)) ) OR ( 5 c decrease ))', query time: 1.65s Refine Results
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  3. 11843

    Lipidomic analysis of epidermis using LC-IMS-CID-MS reveals major changes in CKO// epidermis. by Kevin J. Mills (9270966)

    Published 2025
    “…See (A) for lipid class nomenclature. (C) Volcano plot illustrates significantly changed lipids in CKO vs K5Cre epidermis, p 0.05 ANOVA, horizontal dashed line represents p 0.05. …”
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    Table 1_Sex-specific association between body mass index and cerebral microbleed progression in adults aged 50–85 years.docx by Cindy W. Yoon (10146428)

    Published 2025
    “…We used a generalized linear mixed model with a negative binomial distribution to assess the association between BMI and the 2-year change in CMB count, and conducted sex-stratified analyses to account for potential sex-specific effects.…”
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    Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

    Published 2018
    “…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
  16. 11856

    Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

    Published 2018
    “…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
  17. 11857

    Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

    Published 2018
    “…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
  18. 11858

    Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

    Published 2018
    “…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
  19. 11859

    A 27-year-old female with an acute cardioembolic infarction fifteen hours after the onset. by Daichi Momosaka (6160418)

    Published 2020
    “…<b>G:</b> MTR<sub>asym</sub> spectra show decreased MTR<sub>asym</sub>(3.5ppm) or APTW signal (%) in the infarct area compared to the CNAWM. mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; FLAIR, fluid attenuated inversion recovery; DWI, diffusion-weighted imaging; ROI, region-of-interest; ADC, apparent diffusion coefficient; APTW, amide proton transfer-weighted; CEST, chemical exchange saturation transfer; CNAWM, contralateral normal-appearing white matter; S<sub>sat</sub>(ppm) and S<sub>0</sub>, the signal intensities obtained with and without selective radiofrequency saturation pulse irradiation, respectively; APT<sub>10</sub>, APT<sub>25</sub>, APT<sub>50</sub>, APT<sub>75</sub>, and APT<sub>90</sub>, correspond to the 10th, 25th, 50th, 75th, and 90th percentiles of APTW signal value, respectively.…”
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