Search alternatives:
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
5 c » 25 c (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
5 c » 25 c (Expand Search)
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11841
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11842
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11843
Lipidomic analysis of epidermis using LC-IMS-CID-MS reveals major changes in CKO// epidermis.
Published 2025“…See (A) for lipid class nomenclature. (C) Volcano plot illustrates significantly changed lipids in CKO vs K5Cre epidermis, p 0.05 ANOVA, horizontal dashed line represents p 0.05. …”
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11844
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11845
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11846
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11847
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11848
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11849
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11850
Table 1_Sex-specific association between body mass index and cerebral microbleed progression in adults aged 50–85 years.docx
Published 2025“…We used a generalized linear mixed model with a negative binomial distribution to assess the association between BMI and the 2-year change in CMB count, and conducted sex-stratified analyses to account for potential sex-specific effects.…”
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11851
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11852
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11853
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11854
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11855
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
Published 2018“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
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11856
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
Published 2018“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
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11857
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
Published 2018“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
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11858
Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
Published 2018“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i><sub>i</sub> ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”
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11859
A 27-year-old female with an acute cardioembolic infarction fifteen hours after the onset.
Published 2020“…<b>G:</b> MTR<sub>asym</sub> spectra show decreased MTR<sub>asym</sub>(3.5ppm) or APTW signal (%) in the infarct area compared to the CNAWM. mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; FLAIR, fluid attenuated inversion recovery; DWI, diffusion-weighted imaging; ROI, region-of-interest; ADC, apparent diffusion coefficient; APTW, amide proton transfer-weighted; CEST, chemical exchange saturation transfer; CNAWM, contralateral normal-appearing white matter; S<sub>sat</sub>(ppm) and S<sub>0</sub>, the signal intensities obtained with and without selective radiofrequency saturation pulse irradiation, respectively; APT<sub>10</sub>, APT<sub>25</sub>, APT<sub>50</sub>, APT<sub>75</sub>, and APT<sub>90</sub>, correspond to the 10th, 25th, 50th, 75th, and 90th percentiles of APTW signal value, respectively.…”
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11860