Video_4_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Image_1_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.JPEG by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Table5_Analysis of Genome-Wide Alternative Splicing Profiling and Development of Potential Drugs in Lung Adenocarcinoma.DOCX by Jing Song (188926)

“…Among them, NVP-AUY922 had the lowest IC50 value and might become a potential drug to prolong a patient’s survival. …”

Image5_Analysis of Genome-Wide Alternative Splicing Profiling and Development of Potential Drugs in Lung Adenocarcinoma.TIF by Jing Song (188926)

“…Among them, NVP-AUY922 had the lowest IC50 value and might become a potential drug to prolong a patient’s survival. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

Polymer–Inorganic Composites with Dynamic Covalent Mechanochromophore by Takahiro Kosuge (2909969)

“…Herein, a rational macromolecular design to suppress the deactivation of activated dynamic mechanophores and improve sensitivity by limiting their molecular motion is proposed. …”

Polymer–Inorganic Composites with Dynamic Covalent Mechanochromophore by Takahiro Kosuge (2909969)

“…Herein, a rational macromolecular design to suppress the deactivation of activated dynamic mechanophores and improve sensitivity by limiting their molecular motion is proposed. …”

Dose- and time-dependent effect of IFN-γ and TNF-α on benzamil-sensitive <i>I</i>_sc and TEER in HBECs. by Anusree Sasidharan (19226521)

Effect of BXL-01-0029 on IFNγ+TNFα-induced class I and class II HLA in Hfsmc. by Luigi Di Luigi (478292)

“…<p>A, Immunocytochemistry revealed no constitutive expression of class I and class II HLA in control Hfsmc (left A); positive staining for both antigens was observed after 24–48 h incubation with IFNγ+TNFα (middle A); BXL-01-0029 significantly counteracted cytokine-induced class II HLA expression at both time points, with no effect onto class I HLA (right A). …”

Digital Microfluidic Platform Based on Printed Circuit Board for Affinity Evaluation of Mertansine Aptamers by Dongliu Xiang (10688647)

“…The dissociation constants (<i>K</i>_d) of the two aptamers are 70.9 ± 8.5 nM and 43.6 ± 21.6 nM, respectively. Compared with manual methods, the digital microfluidic platform not only reduced the time for a single determination from 105 to 45 min but also significantly decreased the reagent consumption from 1280 to 30.72 μL. …”

Source data. by Praneet Kaur Sandhu (21156149)

“…We found that DDX5 and DDX17 are required for gammaherpesviral lytic reactivation and loss of both DDX5 and DDX17 decreased KSHV and EBV lytic reactivation. …”

Dose- and time-dependent effect of IL-13, IL-4, and TGF-β1 on benzamil-sensitive <i>I</i>_sc and TEER in HBECs. by Anusree Sasidharan (19226521)

Electrospinning Nonspinnable Sols to Ceramic Fibers and Springs by Shiling Dong (14855228)

“…However, the addition of polymers to the spinning solution makes the process more complex, increases the processing time, and results in porous mechanically weak ceramic fibers. Herein, we develop a coelectrospinning technique, where a nonspinnable sol (<10 mPa s) consisting of only the ceramic precursor(s) and solvent(s) is encapsulated inside a polymeric shell, forming core–shell precursor fibers that are further calcined into ceramic fibers with reduced porosity, decreased surface defects, uniform crystal packing, and controlled diameters. …”

Electrospinning Nonspinnable Sols to Ceramic Fibers and Springs by Shiling Dong (14855228)

“…However, the addition of polymers to the spinning solution makes the process more complex, increases the processing time, and results in porous mechanically weak ceramic fibers. Herein, we develop a coelectrospinning technique, where a nonspinnable sol (<10 mPa s) consisting of only the ceramic precursor(s) and solvent(s) is encapsulated inside a polymeric shell, forming core–shell precursor fibers that are further calcined into ceramic fibers with reduced porosity, decreased surface defects, uniform crystal packing, and controlled diameters. …”

Electrospinning Nonspinnable Sols to Ceramic Fibers and Springs by Shiling Dong (14855228)

“…However, the addition of polymers to the spinning solution makes the process more complex, increases the processing time, and results in porous mechanically weak ceramic fibers. Herein, we develop a coelectrospinning technique, where a nonspinnable sol (<10 mPa s) consisting of only the ceramic precursor(s) and solvent(s) is encapsulated inside a polymeric shell, forming core–shell precursor fibers that are further calcined into ceramic fibers with reduced porosity, decreased surface defects, uniform crystal packing, and controlled diameters. …”

Electrospinning Nonspinnable Sols to Ceramic Fibers and Springs by Shiling Dong (14855228)

“…However, the addition of polymers to the spinning solution makes the process more complex, increases the processing time, and results in porous mechanically weak ceramic fibers. Herein, we develop a coelectrospinning technique, where a nonspinnable sol (<10 mPa s) consisting of only the ceramic precursor(s) and solvent(s) is encapsulated inside a polymeric shell, forming core–shell precursor fibers that are further calcined into ceramic fibers with reduced porosity, decreased surface defects, uniform crystal packing, and controlled diameters. …”

Metabolic effects of EPO (open circles) compared with vehicle control (closed circles) in series <i>HS-50_BV</i>, <i>HS-65_BV</i>, and <i>HS-65_BV+VP<... by Vesna Borovnik-Lesjak (653673)

Wide-Range Linear Iontronic Pressure Sensor with Two-Scale Random Microstructured Film for Underwater Detection by Shaowei Wu (1832599)

“…Herein, we design a two-scale random microstructure ionic gel film with rich porosity and a rough surface. …”

Wide-Range Linear Iontronic Pressure Sensor with Two-Scale Random Microstructured Film for Underwater Detection by Shaowei Wu (1832599)

“…Herein, we design a two-scale random microstructure ionic gel film with rich porosity and a rough surface. …”