Cytokines and chemokines in lung tissue after sham procedure or double hit (DH) in wild type (wt) mice (black bars) or in absence of C5 (C5^-/-) mice (grey bars). Systemi... by Miriam Kalbitz (3150195)

“…<b>F</b>. Increased MCP-1 plasma concentrations in wt mice after DH, decrease of MCP-1 after DH in absence of C5. …”

PPE-induced lung emphysema is exacerbated in Gal-9–deficient mice. by Yuko Horio (4243405)

“…Numbers of lymphocytes and macrophages and the levels of MMP-9, MMP-2 and TIMP-1 did not differ between WT mice and Gal-9-deficient mice (n = 4 per group) (D and E). …”

Effect of cilostazol on Aβ-induced cytotoxicity. by Hye Rin Lee (616252)

KIF4 motor activity is required for the surface NTCP expression. by Sameh A. Gad (12269979)

Modeling of the BXA-rPA_N binding interface of A(H1N1)pdm09 with E23G/K. by Jeremy C. Jones (9248188)

“…<p><b>A)</b> The I38T substitution (dotted circle) leads to a significant decrease in van der Waals interactions between residue 38 and the hydrophobic sulfur-containing tricyclic system of BXA. …”

Mutation-Induced Loop Opening and Energetics for Binding of Tamiflu to Influenza N8 Neuraminidase by Parimal Kar (1330071)

“…Considering the mutant N8 variants in the open conformation adopted during the simulations, we observe a significant loss in the size of the total binding free energy for the N8_Y252H–OTV, N8_H274Y–OTV, and N8_R292K–OTV complexes compared to N8_WT–OTV, mainly due to the decrease in the size of the intermolecular electrostatic energy. …”

<i>cbf11</i> interacts genetically with <i>sty1</i> and <i>pka1</i> pathways. by Martin Převorovský (209870)

“…<b>(C)</b> Calcofluor staining documents that the occurrence of <i>Δcbf11</i>-associated septation defects (e.g., single cells with multiple septa) is decreased in the double mutants with <i>sty1</i> and <i>pka1</i>. …”

Model of the <i>D</i>. <i>discoideum</i> autophagic response during <i>M</i>. <i>marinum</i> infection. by Elena Cardenal-Muñoz (341021)

“…<p>Early after engulfment, <i>M</i>. <i>marinum</i> damages the membrane of its MCV in an ESX-1-dependent manner. …”

<i>P</i>. <i>aeruginosa</i> pyoverdine promoter induction is affected by multiple <i>S</i>. <i>aureus</i> secreted factors. by Tiffany M. Zarrella (12902741)

“…<i>aureus</i> WT supernatant, water, or 10X fractions with or without proteinase K treatment (mixed 1:1 with medium). …”

Acute knock-down of <i>Bin1</i> in the hippocampus of PS19^Hemi mice results in neuronal loss. by Kathleen M. McAvoy (7224863)

Schematic illustration of the mechanism of CB2R activation inhibits NLRP3 inflammasome in peritoneal macrophages. by Ping Ke (3110763)

CB2R inhibits NLRP3 inflammasome activation and augments autophagy in colon from DSS-induced colitis mice. by Ping Ke (3110763)

“…**P<0.01 <i>vs</i>. WT. (C) HU 308 significantly increased the expression of LC3-II/LC3-I, Beclin-1 and decreased the expression of SQSTM1. n = 6 per group. …”

CB2R augments autophagy in peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

“…(A) Pre-incubated with HU 308 significantly increased the level of LC3-II/LC3-I, Beclin-1 and decreased the level of SQSTM1. n = 6 per group. …”

CB2R negatively regulates NLRP3 inflammasome activation in peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

“…WT, ##P<0.01 <i>vs</i>. WT.</p>…”

<i>trxr-1</i> and <i>gsr-1</i> mutant worms are defective in phototaxis response. by Wenyuan Zhang (3724807)

“…Following such pre-exposure, the worm was then tested for phototaxis behavioral response with a standard testing light pulse (2 sec). <i>trxr-1(sv47)</i> and <i>gsr-1(xu414)</i> mutants exhibited a faster decrease in phototaxis response compared to WT. …”

SFN treatment impairs STAT5A-1*6-mediated survival and growth of Ba/F3 cells. by Carina Michl (2837918)

“…By contrast, STAT5A-1*6 phosphorylation decreased after 5 days of treatment with 2 μM SFN.…”

Phosphoproteomics Profiling Reveals Key Proteins Involved in Neuroinflammation and Impaired Axon Guidance Induced by Bilirubin Deficiency by Ming Chen (115604)

“…Golgi staining further revealed reduced number of dendritic intersections, branch points, shortened neurite length, and decreased dendritic complexity in <i>Blvra</i>^{<i>–/–</i>} mice compared to WT mice. …”

Adjusted associations between positive environment swabs and household characteristics and reported behaviors. by Sheila K. West (7245476)

Aging effects on airflow dynamics and lung function in human bronchioles by JongWon Kim (611892)

“…</p><p>Findings</p><p>The airway mechanical characteristics decreased with aging, specifically a 38% pressure drop was observed for the 80-year-old as compared to the 50-year-old. …”

Role of the phosphorylation of ATF7 in G2/M progression. by Hitomi Hasegawa (697973)