GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

Porcupine plots of the PCA analysis depicting the movement and altitude of the C-alpha atoms throughout the 50 ns simulation in the native and mutant complexes. by Sneha P. (3926957)

Supplemental Material for MSG L-00273-2023R1;Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice by Sadis Matalon (13571353)

A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

“…To date, several autotaxin/ENPP2 inhibitors have been reported; however, none were able to completely and continuously inhibit autotaxin/ENPP2 <i>in vivo</i>. In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”

(A) Modulation transfer function (MTF) and (B) normalized point spread function (PSF) of the non-accelerated (blue) and 1D-accelerated (1-shot = red, 2-shot = green) readouts. by Marta Vidorreta (763620)

The percent of students who, if a science instructor were to tell a joke about a specific subject, might find the joke funny and might find the joke offensive. by Katelyn M. Cooper (5634851)

Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ul... by Othmar Moser (789838)

“…</p><p>Results</p><p>BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. …”

IC₅₀ of indole alkaloid against lipase [23]. by Atikarn Janthongkaw (17020498)

The optimization algorithm to identify ideal conditions for detection of epistasis is exemplified through the 3D scatter plot of three different measures of LD. by Gabriele Pedruzzi (5753792)

3D model and section view of E3 NGV. by Decang Lou (21439960)

“…The results reveal that the large deviation in the manufactured vane (up to 0.5 mm at the leading edge) alters the direction of the coolant flowing out from the leading-edge film-cooling holes, affects the film coverage along the surface, and in consequence, causes the temperature near the stagnation point increasing by approximately 40 K. Furthermore, variations in coolant inlet pressure, decreasing by 10 kPa, and temperature, increasing by 10 K, result in the vane surface temperature increased by 20 ~ 30 K. …”

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

Subjects:

Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

“…In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM). …”

Gene clustering identifies up- and down-regulated groups that control development, pluripotency, and cell division. by Michael Shelton (382572)

“…<p>Pluripotent H9 hESCs were differentiated for 50 days as previously described [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0222946#pone.0222946.ref012" target="_blank">12</a>], beginning with high (7.5 μM or 10 μM) CHIR99021 concentrations. mRNA samples from the indicated time points were subjected to gene expression profiling. …”

Table_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.DOCX by Kai Yang (73590)

Image_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.TIF by Kai Yang (73590)

T310A mutation decreases TSP50’s ability to interact with NF-κB:IκBα complex and to promote NF-κB signaling. by Yu-Yin Li (323887)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

C2GnT1 gene knockdown decreases C2-O-sLe^X glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

“…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”

Differential gene expression assay EC₅₀ values in Huh-7 cells and PHH. by Xuan G. Luong (9761423)