Effect of specific inhibitors on CYP-mediated CK (50 μM) metabolism in HLMs. by Jian Xiao (253329)

“…In the presence of sulfaphenazole (1 μM) and ketoconazole (1 μM), the metabolic clearance rate of CK decreased to 73.5% and 74.6% of that of the control, respectively, whereas the other inhibitors had no significant inhibitory effects on the metabolism of CK.…”

Fig 5 - by Evelyn Medawar (9774392)

Non-Pneumatic Anti-Shock Garment (NASG), a First-Aid Device to Decrease Maternal Mortality from Obstetric Hemorrhage: A Cluster Randomized Trial by Suellen Miller (294598)

“…We hypothesized the NASG group would have a 50% reduction in adverse outcomes.…”

Data_Sheet_1_The Risky Decrease of Fishing Reference Points Under Climate Change.docx by Morgane Travers-Trolet (548023)

“…The model was first parameterized and run to fit the historical situation (2000–2009) and then used to assess the ecosystem state for the 2050–2059 period, using two contrasting climate change scenarios (RCP 4.5 and RCP 8.5). For each condition, a monospecific MSY estimation routine was performed by varying species fishing mortality independently and allowed estimation of reference points for each species. …”

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

Activity relative deviation values for every experimental set-up, detector and source combination plotted against the respective SNR values. by Antanas Bukartas (10023785)

Response of small airway tissues infected with EV-D94 and decreasing doses of EV-D68. by Ines Cordeiro Filipe (5849144)

“…<p>Tissues were infected with 1E7 RNA copies of EV-D94 (equivalent to 2,46E4 TCID50) and 1E7 RNA copies of EV-D68 (3,3E5 TCID50) as well as decreasing doses of the latter. …”

Lateral position relative deviation values for every experimental set-up, detector and source combination plotted against the respective SNR values. by Antanas Bukartas (10023785)

Longitudinal position relative deviation values for every experimental set-up, detector and source combination plotted against the respective SNR values. by Antanas Bukartas (10023785)

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Shortening of mTL anticipates accumulation of DDR markers, decrease in cell proliferation and increase in apoptotis with age. by Madalena C. Carneiro (102302)

“…Proliferative tissues, A) gut B) kidney marrow and C) testis, show a sustained decrease in cell proliferation by 12 months of age in <i>tert</i>^<i>-/-</i> (panels g, i) and by 36 months in WT tissues (panels f, h and j). …”

DMB treatment decreased neuronal apoptosis in cerebral ischemia. by Huinan Zhang (849524)

Summary plot for the effect of important food sources of fructose-containing sugars on diastolic blood pressure (DBP). by Qi Liu (33068)

Fixation becomes unlikely with decreasing fitness of mutant homozygotes, variance in allele frequency increases with migration rate. by Philipp M. Altrock (340203)

Coordinates of O_i point in cylindrical coordinate system. by Weiliang Zhang (11231646)

Digraph showing relationships (arrows) for which we need accurate information in order to accurately predict species–specific shorebird responses to climate change. by Hector Galbraith (636637)