Targeting pan-caspase activation suppresses HIV-1 infection. by Jason Segura (14608801)

“…Primary CD8-depleted PBMC were infected with HIV-1_BAL for 6 days in the presence of 50uM indicated caspase inhibitors and analyzed for the accumulation of p24+/CD62L- populations (<b>A</b>) as well as the level of infection using intracellular p24 staining (<b>B</b>). …”

Supplementary Material for: The current status of tumor markers as biomarkers in the era of immunotherapy for hepatocellular carcinoma: alpha-fetoprotein alone is not sufficient by Hiraoka A. (4273894)

Sperm motility is altered in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} mice. by Seiya Oura (9234312)

“…<p><b>(A)</b> Curvilinear velocity (VCL) and <b>(B)</b> average path velocity (VAP) values were reduced in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} sperm. <b>(C)</b> The straight-line velocity (VSL) was not changed in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} sperm. …”

The core model with an additional intracellular feedback is superior and gene expression upon downregulation of IRF family members. by Katharina Robichon (8445099)

“…(<b>H</b>) Gene expression upon decreased <i>IRF8</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF8</i> (red), against <i>IRF8</i> and <i>IRF2</i> (lilac) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”

Admission Blood Glucose Level and Its Association With Cardiovascular and Renal Complications in Patients Hospitalized With COVID-19 by Tom Norris (7380536)

De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. by Sarfraz Shafiq (13259589)

“…Only TEs with padj > 0.05 are displayed. <b>(C)</b> Volcano plot showing retroelement loci with increased (blue) and decreased (red) transcript levels in ATRX-null compared to control microglia. …”

Biochemical data. by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Image_1_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.tif by Mengting Chen (1419172)

“…Furthermore, JK5G administration significantly decreased the levels of pro-inflammatory markers, including TNF-α, IL-2, and C-reactive protein (CRP) (all p < 0.05). …”

Scoring of Disease Activity Index (DAI). by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Image_2_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.tif by Mengting Chen (1419172)

“…Furthermore, JK5G administration significantly decreased the levels of pro-inflammatory markers, including TNF-α, IL-2, and C-reactive protein (CRP) (all p < 0.05). …”

Primers sequences used in this study. by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

DataSheet_1_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.doc by Mengting Chen (1419172)

“…Furthermore, JK5G administration significantly decreased the levels of pro-inflammatory markers, including TNF-α, IL-2, and C-reactive protein (CRP) (all p < 0.05). …”

DataSheet_2_WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.docx by Wenyan Li (255305)

“…Bioinformatic analyses showed that compared with wild type (WT), WAS knock out (KO)-CD4⁺ TEM cells exhibited increased Simpson index and decreased D50 index (P <0.05); The rank abundance curve of KO-CD4⁺ TEM cells was shorter and steeper than that of WT, and the angle of ^qD and q in KO-CD4⁺ TEM cells was lower than that of WT, while these indexes showed few changes between WT and KO chimeric mice in the CD8⁺TCM population. …”

DataSheet_1_WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.zip by Wenyan Li (255305)

“…Bioinformatic analyses showed that compared with wild type (WT), WAS knock out (KO)-CD4⁺ TEM cells exhibited increased Simpson index and decreased D50 index (P <0.05); The rank abundance curve of KO-CD4⁺ TEM cells was shorter and steeper than that of WT, and the angle of ^qD and q in KO-CD4⁺ TEM cells was lower than that of WT, while these indexes showed few changes between WT and KO chimeric mice in the CD8⁺TCM population. …”

Image_1_Combined application of melatonin and Bacillus sp. strain IPR-4 ameliorates drought stress tolerance via hormonal, antioxidant, and physiomolecular signaling in soybean.jpe... by Odongkara Peter (18861397)

“…Likewise, Bacillus–melatonin-treated plants enhanced the uptake of magnesium, calcium, and potassium by 31.2%, 50.7%, and 30.5%, respectively. Under the same conditions, the salicylic acid content increased by 29.1%, whereas a decreasing abscisic acid content (25.5%) was observed. …”

DataSheet_1_Combined application of melatonin and Bacillus sp. strain IPR-4 ameliorates drought stress tolerance via hormonal, antioxidant, and physiomolecular signaling in soybean... by Odongkara Peter (18861397)

“…Likewise, Bacillus–melatonin-treated plants enhanced the uptake of magnesium, calcium, and potassium by 31.2%, 50.7%, and 30.5%, respectively. Under the same conditions, the salicylic acid content increased by 29.1%, whereas a decreasing abscisic acid content (25.5%) was observed. …”

Data_Sheet_1_The Associations of Plasma Carotenoids and Vitamins With Risk of Age-Related Macular Degeneration: Results From a Matched Case-Control Study in China and Meta-Analysis... by Hong Jiang (79543)

“…Associations for β-carotenes (OR: 0.11; 95% CI: 0.02, 0.50; P_trend < 0.001), and β-cryptoxanthin (OR: 0.08, 95% CI: 0.02, 0.39; P_trend < 0.001) were similar to that for lutein/zeaxanthin. …”

Effects of HTK on H₂O₂ scavenge in a neuron-free system. by Jiun Hsu (7365779)

“…Data are expressed as means ± SEMs (n = 6). *P < 0.05 vs. PBS at the same concentration of H₂O₂.…”

Larvicidal and macrofilaricidal efficacy of Closantel and Morantel against mosquito larvae and <i>Setaria digitata</i> nematodes by Megan Hall (506400)

“…While malaria incidence in India has decreased by nearly 50% in recent years, India holds 66% of the WHO SEA region’s malaria burden (World Malaria Report, 2023, Singh et al., 2024). …”

Sequence conservation and coverage analysis, predicted accuracy of models, and prediction of metal-binding residues of ZepA from <i>Anabaena</i> and <i>Lacipirellula limnantheis</i... by Cristina Sarasa-Buisan (12627973)

“…In the 5 models, accuracy decreased between 30 and 70 at the 10 N-terminal amino acids (pLDDT < 50) predicting a disordered region (unstructured under physiological conditions). …”