Showing 1 - 20 results of 31,437 for search '(( 50 ((026 decrease) OR (_ decrease)) ) OR ((( 16 we decrease ) OR ( 5 wt decrease ))))', query time: 0.57s Refine Results
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    GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

    Published 2021
    “…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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    Stability scores with refinement and no USM decreases. by Jedediah M. Singer (10331212)

    Published 2022
    “…<p>Effects of guided and random substitutions within expert-designed proteins, when guided substitutions are not permitted to decrease USM EC<sub>50</sub> predictions.</p> <p>(EPS)</p>…”
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    DAF-16/FOXO is Required for Locomotory Healthspan and Lifespan Benefits of Genetic Glycolysis Disruption. by Brian Onken (86790)

    Published 2020
    “…WT later in life [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref091" target="_blank">91</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref092" target="_blank">92</a>]; we note that, although comparison of scores across experiments is not possible due to variation in baseline values, the swimming rate of <i>daf-16(mgDf50)</i> control animals was slightly lower than WT controls on the same day of life (in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.g001" target="_blank">Fig 1C</a>; mean of 46.17 head thrashes/30 sec. for <i>daf-16</i> vs. 52.17 head thrashes/30 sec. for WT on day 10). …”
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    Disrupting Glycolysis-promoting Genes Extends <i>C</i>. <i>elegans</i> Healthspan, Whereas High Glucose and Gluconeogenic Gene Disruptions Shorten Healthspan. by Brian Onken (86790)

    Published 2020
    “…We recorded the number of head bends (i.e. head “thrashes”) / 30 seconds for individual animals placed in liquid media on day 8 of life. 4% glucose significantly decreases WT locomotory ability (*** <i>P</i> = 0.0005, unpaired t test; averages from three trials, n = 30 animals per condition; error bars represent SEM). …”
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    Statistical details of data presented in Fig 16. by Piotr Popik (292215)

    Published 2024
    “…<div><p>The rapid decrease of light intensity is a potent stimulus of rats’ activity. …”