Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Prolonged enhancement of spinal network activity decreases the intrinsic excitability of spinal motoneurons. by Joseph Lombardo (5007317)

The stability of electroporated mRNAs is also significantly decreased in serum-starved cells by Ruth Seal (6671)

“…</p><p>© 2005, the authors © </p> () Five reporter mRNAs containing the luciferase open reading frame (luc) or luc plus additional sequences in the 3′ UTR derived from a random 50mer (luc–N50–3′UTR), COX 4 (luc–cox), or two variants of the COX 4 3′ UTR (luc–cox84 and luc–cox12) were individually electroporated into serum-starved or serum-stimulated Hep G2 cells. …”

ku0063794 but not rapamycin decreased the TRPC6 mRNA levels in podocytes. by Fangrui Ding (659863)

“…<p>(A) ku0063794 (2 µmol/l) or rapamycin (50 nmol/l) was applied to evaluate the effects of mTORC1 and mTORC2 on TRPC6 in podocytes. …”

LC3-II immunohistochemistry in PCs was decreased in ET cases vs. controls. by Sheng-Han Kuo (292031)

eNOS^-/- decreased synaptic protein expression in the ischemic brain. by Xu Cui (261214)

Inhibition of SNAI2 expression decreases the sensitivity to chemotherapy drugs of HCC cells. by Xin-Yu Zhao (3228756)

Vinculin protein levels are severely decreased in Paxillin- and FAK-deficient zebrafish embryos. by Sofia Hirth (2556928)

Transient silencing of APIP decreases the growth of the HeLa cells in MTA medium. by Camille Mary (291547)

Decreased cell proliferation rate and increased apoptosis in hICD-expressing cells. by Shixuan Wang (136189)

VASH1 controls SOD2 level and decreases ROS level in HUVECs. by Hiroki Miyashita (131087)

The apparent Ca²⁺ affinity of release is decreased by hydrophobic mutations. by Matthew R. Bowers (8423115)

“…The significant rightward shift in the curve (EC50, non overlapping confidence intervals) indicates a decrease in the apparent Ca²⁺ affinity of neurotransmitter release.…”

Population dynamics of <i>Killer-Rescue</i>/Cargo, ClvR and split^50cM <i>ClvR</i> for elements with different fitness costs, and introduction percentages. by Georg Oberhofer (3401438)

FoxO3 silencing decreases high glucose-induced apoptosis in CMECs. by Chaoming Peng (486198)

CD163+ macrophage infiltration is decreased in nNOS TG+/dko muscle. by Michelle Wehling-Henricks (342479)

Mitochondrial function decreases in pasture-fed dairy cows during early lactation. by Mercedes García-Roche (6459200)

Significantly decreased CBF regions of PTSD group compared with non-PTSD group. by Yang Liu (4829)

Significantly decreased CBF region of PTSD group compared with non-PTSD group. by Yang Liu (4829)

Fiber length changes to ramp decreases in force applied at steady isometric force. by Haruo Sugi (576292)

“…<p>Ramp decreases in force from the level of steady Ca²⁺-activated isometric force to zero (complete in 0.15–0.3 s) were applied to one and the same muscle fiber at KCl concentrations of 0 mM (A), 50 mM (B), and 125 mM (C).…”

TL decreases cell viability in malignant cells dependent of p53 status. by Ajay Kumar (192967)