Capsaicin inhibited the proliferation of human SCLC cells in a time- and concentration-dependent manner. by Kathleen C. Brown (365508)

“…<p>(A) MTT assays show at the treatment of H69 and H82 cells with 50 µM capsaicin causes a decrease in cell viability starting from 24 hours to 72 hours. …”

Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism by Goran Lakisic (2551717)

“…However, its physiological roles remain unknown. Here, we demonstrate that ablation of the <i>Bahd1</i> gene results in hypocholesterolemia, hypoglycemia and decreased body fat in mice. …”

An HIV-1 Envelope Immunogen with W427S Mutation in CD4 Binding Site Induced More T Follicular Helper Memory Cells and Reduced Non-Specific Antibody Responses by Hao-Tong Yu (697936)

“…We constructed a gp120 mutant W427S of an HIV-1 primary R5 strain and examined its ability in the elicitation of Ab and the production of Tfh by immunization of BALB/c mice. …”

The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology by Mohsen Sadatsafavi (63962)

“…Even after adjusting for observable characteristics, individuals in the 97.5th percentile of exacerbation rate had 5.6 times higher rate of severe exacerbations than those in the 2.5th percentile.…”

Supplementary Material for: Eppikajutsuto Protects against Food Allergy Induced by Ovalbumin in a Murine Model by Matsui T. (4061857)

“…Evaluated FA symptoms included a decrease in body temperature and allergic diarrhea. …”

Possible pathways involved in GBE-induced neuroplasticity pathway. by Imane Lejri (8066507)

The leaf-air temperature difference reflects the variation in water status and photosynthesis of sorghum under waterlogged conditions by Ruidong Zhang (6637526)

“…Waterlogging stress was imposed at the sorghum five-leaf stage. The leaf free water content (FWC) and relative water content (RWC) decreased under the waterlogged condition. …”

Reduced RNA expression of the <i>FMR1</i> gene in women with low (CGG_n<26) repeats by Qi Wang (22418)

“…While it would be of interest to see whether FMRP is also decreased in the low-group we recognize that in recent years it has been increasingly documented that information flow of genetics may be regulated by non-coding RNA, that is, without translation to a protein product. …”

Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes by François Dion (3990335)

“…The effect of chronic kidney disease on insulin resistance was studied on two different rat strains. First, in a 5/6^th nephrectomised Sprague-Dawley rat model of chronic kidney disease, we observed a correlation between the severity of chronic kidney disease and hyperglycemia as evaluated by serum fructosamine levels (p<0.0001). …”

Cyclin G2 is a target molecule of Cn/NFATc2 in follicular keratinocytes. by Atsushi Fujimura (227683)

“…<p>(A) The microarray analysis identified 24 genes that showed down-regulated expression in PHK cells treated with either 11R-VIVIT or CsA; <i>ccng2</i> (cyclin G2) expression showed the greatest decrease after Cn/NFAT inhibition. …”

Modulation of HS α4β2 receptors with a low concentration of arecoline. by Roger L. Papke (685990)

“…After 8 minutes the responses to a control application of ACh was reduced approximately 50%. …”

Table_1_Iodine contrast exposure and incident COVID-19 infection.DOCX by Karen Tsai (14199629)

“…Limited in vitro and in vivo data suggest that iodine exposure may rapidly inactivate, reduce transmission, and reduce infectivity of SARS-CoV-2. We hypothesized that iodine exposure may be associated with decreased incident COVID-19 infection.…”

Laboratory selection of <i>Aedes aegypti</i> field populations with the organophosphate malathion: Negative impacts on resistance to deltamethrin and to the organophosphate temepho... by Priscila Fernandes Viana-Medeiros (5729189)

“…In the control groups resistance to all evaluated insecticides decreased except, unexpectedly, to deltamethrin. Analysis of the main resistance mechanisms employed routine methodologies: biochemical and molecular assays for, respectively, metabolic resistance and quantification of the Na_V pyrethroid target main <i>kdr</i> mutations at positions 1016 and 1534. …”

DataSheet1_Examining the paradoxical effects of kratom: a narrative inquiry.PDF by Kirsten E. Smith (10716529)

“…Five of the 10 participants met DSM-5-based criteria for kratom-use disorder (3 mild, 1 moderate, 1 severe, by symptoms counts). …”

Fig 7 - by P. R. Hut (12152350)

Data_Sheet_1_Are Reduced Levels of Coagulation Proteins Upon Admission Linked to COVID-19 Severity and Mortality?.PDF by Francisco C. Ceballos (8065037)

Statin Effects on Aggression: Results from the UCSD Statin Study, a Randomized Control Trial by Beatrice A. Golomb (140574)

“…In men, statins tended to decrease aggression, significantly so on pravastatin: difference=-1.0(SE=0.49)P=0.038. …”

Factors associated with postoperative signs and symptoms in teeth with periapical lesion: a longitudinal study by Erlange Andrade Borges Silva (14224193)

“…Female gender (beta = 1.02; p < 0.01), mandibular teeth (beta = 25.50; p < 0.01), medium root canal amplitude (beta = 0.93; p = 0.03), and edema (beta = 1.88; p < 0.01) were associated with increased postoperative pain and tenderness, while the use of analgesics (beta = -1.82; p < 0.01) and time in days (beta = -0.23; p < 0.01) were associated with a decrease in these signs and symptoms. …”

Crystal structure and cytotoxic activities of a bis(pyrrolyl-imine) gold(III) complex by Daniel De Moraes Profirio (2885411)

“…Cytotoxic activity of [Au(pyren)]⁺ was active against three tumorigenic cell lines with IC₅₀ values of 35 μM. Interaction studies with CT-DNA by fluorescence and competition with ethidium bromide (EB) showed a quenching of the emission band of DNA with a Stern–Volmer quenching constant value of (3.0 ± 0.1) × 10⁴ M⁻¹ and a decrease in fluorescence quenching of EB-DNA system, respectively, confirming that DNA is a possible target for the complex via an intercalative binding, which was confirmed by DNA conformational changes observed with circular dichroism spectroscopy.…”

<i>S. aureus</i> RnpA catalyzes rRNA and mRNA digestion. by Patrick D. Olson (230450)

“…The band at ∼17.2 kDa (solid arrow; Band 2) was confirmed to be <i>S. aureus</i> RnpA by tandem mass spectrometry (Wistar Institute; Philadelphia, PA), whereas top-hits for minor contaminants (dashed arrows) were determined to be <i>E. coli</i> 50S ribosomal protein L3 (Band 1) or <i>S. aureus</i> RnpA polypeptide fragments, corresponding to amino acids 11–107 (Bands 3 and 4) or 12–107 (Band 5). …”