Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Analysis of Y dLGN cells whose percentage of response in burst was less than 40–50%. by Nelson Espinosa (356237)

“…<p>rTMS@1Hz increased the percentage of spikes in burst <i>(</i><b><i>A</i></b><i>)</i> and consequently decreased tonic spikes <i>(</i><b><i>B</i></b><i>).…”

The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity by Paola Larghi (131929)

“…We propose that nuclear accumulation of the p50 NF-κB subunit in DC, as occurring during lipopolysaccharide-driven maturation, is a homeostatic mechanism tuning the balance between uncontrolled activation of adaptive immunity and immune tolerance.…”

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3 by Chia-Ling Wu (114083)

“…<em>Trim63 (MuRF1)</em>, <em>Fbxo32</em> (<em>MAFbx</em>), <em>Ubc</em>, <em>Ctsl</em>, <em>Runx1</em>, <em>Tnfrsf12a</em> (Tweak receptor), and Cxcl10 (<em>IP-10</em>) showed increased Bcl-3 binding to κB sites in unloaded muscle and thus were direct targets of Bcl-3. p50 binding to the same sites on these genes either did not change or increased, supporting the idea of p50:Bcl-3 binding complexes. p65 binding to κB sites showed decreased or no binding to these genes with unloading. …”

Myosin phosphatase and RhoA-activated kinase modulate neurotransmitter release by regulating SNAP-25 of SNARE complex by Dániel Horváth (4015034)

“…Inhibition of PP1 with tautomycetin increased, whereas inhibition of ROK by H1152, decreased the phosphorylation of SNAP-25 at Thr138 in B50 cells, in cortical synaptosomes, and in brain slices. …”

LD- and haplotype-based measures of epistasis identify a narrow time window of epistasis detectability. by Gabriele Pedruzzi (5753792)

miR expression after 24 hours of 50% nutrient restriction in HTR8 trophoblast cells. by Shanthie Thamotharan (3992894)

Recommendations of no-fly zones for the colonies of common terns, Sandwich terns, black headed gulls, herring gulls and lesser black-backed gulls, great cormorants and Eurasian spo... by Estefania Velilla (22566709)

TG6-44 treatment leads to a decrease in NP-positive cells and altered expression patterns of NP in A/X31 infected THP-1 cells. by Juan A. De La Cruz (11154187)

MRPP A-statistics from pairwise comparisons plot distance classes for lichen, vascular plant and bryophyte communities. by Peter N. Neitlich (4034300)

Subjects:

Effectiveness of E cytotoxicity presented as a half maximal growth inhibitory concentration (CC₅₀). by Anna Kalota (7415)

Contemporary mean inundation fraction in the Amazon basin. by Nic Gedney (19762301)

Area estimates in CAKR by percentage of the mean LSR of the 3000–4000 m distance class (41.9) according to the posterior predictions model. by Peter N. Neitlich (4034300)

Subjects:

Soil Carbon Stocks Decrease following Conversion of Secondary Forests to Rubber (<i>Hevea brasiliensis</i>) Plantations by Marleen de Blécourt (435325)

SHIP-1 PRD region is necessary and sufficient to decrease NOD2-induced NF-κB activity. by Claude Condé (150801)

Fig 7 - by Finn Egil Skjeldestad (7821716)

Subjects:

Proteasome inhibition impairs radiation-induced DNA double strand break (DSB) repair by decreasing homologous recombination. by Kyle R. Cron (455028)

<i>Pax7</i> positive cells decrease during <i>in vitro</i> differentiation of myogenic progenitors. by Cécile Rallière (86527)

Inhibition of ACC leads to decreased de novo lipogenesis in both U87 and U87 EGFRvIII but reduced the number of U87 EGFRvIII cells to a greater extent. by Jessica E. C. Jones (541168)

The mean <i>z</i>-coordinate error decreasing percentages (%) of SSI-RIK compared to EM-SFM, CSF and RIK, when the sequence sizes vary from 15 to 50 with an equal interval 5. by Ya-Ping Wang (44525)

“…<p>The mean <i>z</i>-coordinate error decreasing percentages (%) of SSI-RIK compared to EM-SFM, CSF and RIK, when the sequence sizes vary from 15 to 50 with an equal interval 5.…”