Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

DataSheet_1_E2F1 mediates competition, proliferation and response to cisplatin in cohabitating resistant and sensitive ovarian cancer cells.docx by Andres Valdivia (16546941)

“…Direct co-culture led to a decrease in the IC50 to platinum in the cisplatin-sensitive cells (5.92 µM to 2.79 µM for PE01, and from 2.05 µM to 1.51 µM for OVCAR5). …”

Data_Sheet_1_Large Gatherings? No, Thank You. Devaluation of Crowded Social Scenes During the COVID-19 Pandemic.pdf by Claudia Massaccesi (10898715)

“…Even people not directly affected by the virus itself were impacted in their physical and/or mental health, as well as in their financial security, by governmental lockdown measures. We investigated whether the combination of these events had changed people's appraisal of social scenes by testing 241 participants recruited mainly in Italy, Austria, and Germany in an online, preregistered study conducted about 50 days after the beginning of the COVID-19 outbreak in Europe. …”

Food restriction increase the expression of mTORC1 complex genes in the skeletal muscle of juvenile pacu (<i>Piaractus mesopotamicus</i>) by Tassiana Gutierrez de Paula (821372)

Dose-response effects for 30 minutes luminal histamine treatment. by Qianru Zhang (292683)

Table_1_Health service providers experience of psycho-emotional violence and associated factors among urban hospitals in Eastern Ethiopia.DOCX by Abebe Tolera (10169854)

“…Improving the working environment decreases the chance of workplace violence; however, there is a lack of guidelines for gender-based violence, the absence of training on coping mechanisms, and spending more time with psychiatric and HIV/AIDS patients’ increases workplace violence. …”

Supplementary Material for: The impact of left ventricular structure and function on mortality in patients with aortic valve infective endocarditis treated with aortic valve replac... by figshare admin karger (2628495)

“…The mean baseline LVEDd was 5.8±0.9 cm in males and 5.0±0.9 cm in females (p<0.001), decreasing to 5.2±0.9 cm in males and 4.7±0.6 cm in females after surgery (p=0.006). …”

Inhibition of collagen cleavage by prostaglandin E(PGE) and transforming growth factor (TGF)-β2 by Elena V Tchetina (38723)

“…<p><b>Copyright information:</b></p><p>Taken from "Prostaglandin PGEat very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and , a gene linked to chondrocyte hypertrophy"</p><p>http://arthritis-research.com/content/9/4/R75</p><p>Arthritis Research & Therapy 2007;9(4):R75-R75.…”

Layer-specific quantification of RS and FS neuronal activity in wM2 across learning. by Vahid Esmaeili (12700352)

“…Left: baseline-subtracted (50 ms prior to whisker onset) population firing rate (mean ± SEM) for different cortical layers (L2/3, L5, and L6a) overlaid for Novice mice (244 neurons in 7 mice) and Expert mice (401 neurons in 11 mice). …”

Supplementary Material for: Anatomical, functional, and prognostic results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions by Chung Y.-R. (20312844)

“…Anatomically, the mean preoperative CMT was 501 ± 168 μm, decreasing to 348 ± 108 μm at month 24 (p=0.008). …”

Impact of Environment and Social Gradient on <em>Leptospira</em> Infection in Urban Slums by Renato B. Reis (90436)

“…</p><h3>Methods and Findings</h3><p>We performed a community-based survey of 3,171 slum residents from Salvador, Brazil. …”

Quantitative Evaluation of Human Cerebellum-Dependent Motor Learning through Prism Adaptation of Hand-Reaching Movement by Yuji Hashimoto (705107)

“…It thus remains unclear how motor learning is influenced by cerebellar diseases or aging, and is related with incoordination. Here, we present a new application for testing human cerebellum-dependent motor learning using prism adaptation. …”

Impact of Oral Semaglutide on Kidney Outcomes in People with Type 2 Diabetes: Results from the SOUL Randomized Trial by Johannes F. E. Mann (22017555)

“…Prespecified kidney outcomes included a 5-point composite (≥50% decrease in estimated glomerular filtration rate [eGFR], persistent eGFR <15 mL/min/1.73 m2, initiation of chronic kidney replacement therapy, or death from kidney or CV causes); a 4-point composite (excluding CV death); and eGFR decline. …”

Image_1_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”

Image_3_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”

Image_2_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”

Low SGZ proliferation and neurogenesis in the dentate gyrus of adult <i>Prnp^0/0</i> mice correlate with high numbers of double labeled NG2-BrdU cells in the molecular la... by Ana Bribián (171285)

“…<p><b>A</b>) Left: Quantification of the number of PSA-NCAM-positive and BrdU-positive cells in dentate gyrus sections from <i>Prnp^+/+</i> and <i>Prnp^0/0</i> mice one day after BrdU-labeling. …”

Protective effects of 20E against H₂O₂-induced cytotoxicity in B35 cells. by Jun Hu (5721)

“…Cells were pretreated with 20E (50 or 400 µM) for 24 h before a 12 h incubation with H₂O₂, and then LDH release (% of total) was calculated as the percentage of LDH in the medium versus total LDH activity in the cells. …”

Generating human striatal organoids. by Xinyu Chen (47670)

“…Data, mean ± SD. One-way ANOVA. *, <i>P</i> < 0.05. Scale bar, 50 μm. …”

Varying the image resolution does not change the relationship between the power law exponents of robust and non-robust models. by Nathan C. L. Kong (11919978)

“…We found that the power law exponents for both robust and non-robust models was lower than that of macaque V1 neural responses and that they decreased as a function of image resolution indicating that increasingly fine stimulus features are encoded as more information is available in the stimulus (top row). …”