(A) Decreasing CaMKII activity by KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L) decreases spontaneous AP firing rate (n = 10 for each drug), cAMP (n = 4 for each drug) and ATP (n = 5 for each drug). by Yael Yaniv (162548)

Synthesis and Activity of a Novel Autotaxin Inhibitor–Icodextrin Conjugate by Natalie Fisher (1860283)

“…The conjugate inhibits autotaxin activity (IC₅₀ = 0.86 ± 0.13 μg mL^–1) and reduces cell migration. …”

DataSheet1_Trained hypertensive rats exhibit decreased transcellular vesicle trafficking, increased tight junctions’ density, restored blood-brain barrier permeability and normaliz... by Vanessa B. Candido (14670266)

Concentration of DRS-B2 and [W/F]³-DRS-B2 that inhibits 50% of cell growth (GI₅₀) extracted from Fig 12. by Célia Dos Santos (306471)

Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer by Sibylle Pfammatter (3226209)

“…However, the FAIMS interface has not been available on older generation Orbitrap mass spectrometers such as the Q-Exactive. Here, we report the integration of the FAIMS Pro device with embedded electrical and gas connections to a Q-Exactive HF mass spectrometer. …”

Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer by Sibylle Pfammatter (3226209)

“…However, the FAIMS interface has not been available on older generation Orbitrap mass spectrometers such as the Q-Exactive. Here, we report the integration of the FAIMS Pro device with embedded electrical and gas connections to a Q-Exactive HF mass spectrometer. …”

Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer by Sibylle Pfammatter (3226209)

“…However, the FAIMS interface has not been available on older generation Orbitrap mass spectrometers such as the Q-Exactive. Here, we report the integration of the FAIMS Pro device with embedded electrical and gas connections to a Q-Exactive HF mass spectrometer. …”

Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer by Sibylle Pfammatter (3226209)

“…However, the FAIMS interface has not been available on older generation Orbitrap mass spectrometers such as the Q-Exactive. Here, we report the integration of the FAIMS Pro device with embedded electrical and gas connections to a Q-Exactive HF mass spectrometer. …”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

(Short-term) viral dynamics. by Sulav Duwal (152805)

Trace-weighted images at b = 50 s/mm². by Tobit Führes (12647099)

table1_Acidic pH Decreases the Endonuclease Activity of Initiator RepB and Increases the Stability of the Covalent RepB-DNA Intermediate while Has Only a Limited Effect on the Repl... by Rafael Valdelvira (10260629)

table1_Acidic pH Decreases the Endonuclease Activity of Initiator RepB and Increases the Stability of the Covalent RepB-DNA Intermediate while Has Only a Limited Effect on the Repl... by Rafael Valdelvira (10260629)

Bacterial strains and plasmids. by Eunsil Choi (8271039)

“…Our previous research showed that deleting <i>bipA</i> in <i>Escherichia coli</i> at 20°C leads to a defect in 50S ribosomal assembly and impaired lipopolysaccharide (LPS) synthesis. …”

SNPs IC₅₀s data at codon 876 during the study period. by Winnie Okore (14139712)

TMD residues decrease sensitivity. by Ákos Nemecz (356830)

“…Glu residues are color coded based upon effect, with residues in red producing a significant decrease in pH₅₀, and in yellow, an insignificant or weak effect, whereas the dark purple and magenta for His residues are synonymous to the red of Glu residues. …”

Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger by Andrea Szentesi (3239193)

“…<div><p>Objective</p><p>Biomedical investment trends in 2015 show a huge decrease of investment in gastroenterology. …”

Relationship between the decrease in hunting licences and excess mortality, in each province: Relationship in 2020–2021 (a), in 2021–2022 (b) and between 2021–2022 licences and 202... by Jacopo Cerri (6271958)

Layer-Thickness-Dependent Strengthening–Toughening Mechanisms in Crystalline/Amorphous Nanolaminates by Xiaoling Zhou (4644826)

“…The mechanical performance of these materials is strongly governed by the crystalline–amorphous interfaces (CAIs), yet the underlying strengthening and toughening mechanisms remain poorly understood. Here, we employ large-scale molecular dynamics simulations to investigate the compressive deformation of C/A nanopillars composed of alternating equal-thickness crystalline Cu and amorphous Cu₅₀Zr₅₀ layers. …”

Layer-Thickness-Dependent Strengthening–Toughening Mechanisms in Crystalline/Amorphous Nanolaminates by Xiaoling Zhou (4644826)

“…The mechanical performance of these materials is strongly governed by the crystalline–amorphous interfaces (CAIs), yet the underlying strengthening and toughening mechanisms remain poorly understood. Here, we employ large-scale molecular dynamics simulations to investigate the compressive deformation of C/A nanopillars composed of alternating equal-thickness crystalline Cu and amorphous Cu₅₀Zr₅₀ layers. …”