Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…The present pilot study represents a novel dietary means by which to reduce BCAA, and as such, provides a blueprint for a potential dietary therapeutic in obesity/diabetes.…”

Supplementary Material for: Phase I Study of CHK1 Inhibitor LY2603618 in Combination with Gemcitabine in Patients with Solid Tumors by Calvo E. (3105135)

“…<i>Results:</i> Among the 50 patients enrolled, frequent adverse events possibly related to study drug treatment included fatigue (44%), decreased platelets (42%), decreased neutrophils (32%), nausea (26%), and decreased hemoglobin (20%). …”

NleF inhibits apoptosis induced by TRAIL and staurosporine. by Sonja Blasche (389494)

“…<p><b>A–C.</b> Percentage of apoptotic HeLa and Caco-2 cells in TRAIL (25 ng/ml) treated (+) and untreated (−) samples. …”

Using Sensitivities To Predict Parameter Compensations for Firing Rate Homeostasis in the Reduced and Realistic Morphologies by Christina M Weaver (84560)

“…</p> <p>(B) As predicted from its firing rate sensitivity (inset barplot), a 10.5% decrease in compensated almost exactly for the effect of the <i>D</i> + <i>SA</i> perturbation on firing rate in (A) (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0040011#s3" target="_blank">Discussion</a> for details). …”

Maturation of GABAergic synaptic and intrinsic properties in primary visual cortex. by Sandra J. Kuhlman (89333)

“…The average IPSC amplitude increased 1.8-fold with age, while the average synaptic decay time-constant decreased roughly 25%, from 5.8 to 4.3 ms. See <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000797#pcbi-1000797-t001" target="_blank">Table 1</a> for statistics. …”

Comparison between the endogenous <i>Igf2</i> transcription levels and the steady state levels of the ectopic RNAs. by Van Giang Tran (162243)

“…<p>In these graphs, we compared, for each transfected <i>H19</i> KO clones, <i>Igf2</i> transcription data shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037923#pone-0037923-g005" target="_blank">Figure 5B</a> with the steady state <i>91H</i> and <i>H19</i> ectopic RNA levels shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037923#pone-0037923-g004" target="_blank">Figure 4B</a>. …”

Cladribine in combination with entinostat synergistically elicits anti-proliferative/anti-survival effects on multiple myeloma cells by Bolun Wang (1465285)

“…Further studies showed that the combinations of cladribine and entinostat as compared to either agent alone more potently induced mitotic catastrophe in the MM cells, and resulted in a marked increase of the cells at G1 phase associated with decrease of Cyclin D1 and E2F-1 expression and upregulation of p21^waf−1. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

MPP2 expression levels influence mIPSC amplitudes. by Bettina Schmerl (669003)

“…<b>(d)</b> Example traces of mIPSC from neurons transduced with control shRNA (black) and MPP2 knockdown shRNA (grey). Scale bar: 100 pA/5s. <b>(e)</b> Knockdown of MPP2 leads to a decrease in average mIPSC amplitude (Mann–Whitney test <i>p</i> = 0.0277). …”

Labeled cells of renin lineage (CoRL) co-express podocin in glomeruli of <i>Ren1cCre /R26R-ConfettiTG/WT</i> mice with experimental FSGS. by Natalya V. Kaverina (3854254)

“…(A²-A⁵) All 4 CoRL reporters (green, red, blue, yellow) can be detected without the use of antibody. …”

Individual Variation in Lipidomic Profiles of Healthy Subjects in Response to Omega-3 Fatty Acids by Malin L. Nording (476302)

“…The EPA lipoxygenase metabolite 12-hydroxyeicosapentaenoic acid (12-HEPE) varied among subjects from an 82% decrease to a 5,000% increase.</p> <p>Conclusions</p><p>Our results show that certain defined responses to ω3 fatty acid intervention were consistent across all subjects. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

Data_Sheet_1_Trends in enrollment, retention, and graduation of United States veterinary technicians/nurses schools.docx by Lori R. Kogan (6517547)

“…Forty-three percent of participants indicated a decrease in student enrollment in the last 5 years. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

CX3CL1 (Fractalkine) Protein Expression in Normal and Degenerating Mouse Retina: <i>In Vivo</i> Studies by Marina Zieger (626340)

“…The immunoblots revealed that in both, wt and rd10 retinas, a membrane integrated ∼100 kDa CX3CL1 form and a cleaved ∼85 kDa CX3CL1 form were present at P5. …”

PPRC1, but not PGC-1α, levels directly correlate with expression of mitochondrial proteins in human dermal fibroblasts by Mateus Prates Mori (10469280)

<i>In vitro</i> antiaggregation and deaggregation potential of <i>Rhizophora mucronata</i> and its bioactive compound (+)- catechin against Alzheimer’s beta amyloid peptide (25–35)... by Natarajan Suganthy (94468)

Temporal changes in mitochondrial density and structure in response to Myc. by J. Anthony Graves (164485)