Showing 441 - 460 results of 27,447 for search '(( 50 ((026 decrease) OR (mean decrease)) ) OR ( 50 ((c decrease) OR (a decrease)) ))', query time: 1.05s Refine Results
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    Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

    Published 2010
    “…Fibroblasts from wild-type (WT) and <i>Als2</i><sup>−/−</sup> mice were either left unstarved (0 hr) (upper) or starved for 6 hr (lower). It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i><sup>−/−</sup> cells. …”
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    GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

    Published 2021
    “…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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