HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Video_3_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_4_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_2_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Data_Sheet_1_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.PDF by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_1_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

E protein residues critical for neutralization by bnAbs. by Jay Lubow (772012)

“…<p>(Left panel) Bar graphs show the mean IC50 fold change against DENV2 16681 reporter virus particles encoding E protein variants relative to wild type (WT) DENV2 for antibodies <b>(A)</b> F09.S05, <b>(B)</b> F05.S03, <b>(C)</b> J9, <b>(D)</b> F25.S02, and <b>(E)</b> EDE1-C10. …”

Response to NLC for 1 122 native plant species with significant null models. by Kaixuan Pan (11714457)

“…<p>3 species with a neutral (without a relationship, named ‘None’) response were omitted as not preferring any NLC. a-h, Response curves of plant species to NLC. i-l, Summary statistics of preferred NLCs. a, Summary of all 1 122 native plants responding to NLC (with percentages in parentheses). b-d, Response curves of species with decreasing (each magenta line indicates one species) (b), unimodal (each blue line indicates one species) (c) and increasing (each green line indicates one species) (d) relations with NLC. …”

Tissular and cellular effects of simulated UV daylight on human reconstructed skin. by Claire Marionnet (244033)

“…In contrast, 13 J/cm² DUVR led to the disappearance of superficial dermal fibroblasts and to the induction of p53 positive keratinocytes (arrows). (c) Samples were sham irradiated (control) or exposed to 7 J/cm² and 13 J/cm² DUVR once a day for 5 consecutive days. …”

GmmSRPN10 is secreted into the midgut lumen and is important for PF infection. by Cher-Pheng Ooi (682424)

“…(D) The knockdown of <i>GmmSRPN10</i> results in a small but significant decrease in PF midgut infection, suggesting that the expression of GmmSRPN10 is important for PF survival (each data point represents a biological replicate, with a total of >300 flies dissected scored for infection per treatment).…”

LET-60 (Ras) activation is sufficient to cause tail swelling and is required for the Dar response to infection. by Rachel McMullan (183027)

“…This decrease was not observed using <i>ras-1(gk237)</i> and <i>ras-2(ok628)</i> mutants that showed a wild-type response to infection (A). …”

Non-invasive brain stimulation demonstrates multistability of macroscopic activity in interconnected networks. by Katrina M. Kutchko (476513)

“…SW had a decreased chance of transitioning to SP.</p>…”

Knockdown of MUC16 enhances dye penetrance compared to knockdown of MUC1. by Ilene K. Gipson (178895)

“…(F) Quantitative image analyses of the area protected from dye penetrance in each cell type demonstrate a significant decrease in area protected from dye penetrance in the MUC16 knockdown cells. …”

REST–less breast cancer tumors display high levels of REST4 splicing and poor prognosis. by Matthew P. Wagoner (247464)

“…REST4 mRNA, was detected in REST–less, but not RESTfl tumors after 35 cycles of amplification. (C) Patients with REST–less breast tumors in the superseries GSE6532, as defined by the 24-gene signature, show a significant decrease in their disease free survival with respect to their RESTfl counterparts (p<0.01).…”

SmedCB RNAi treatment reduces cathepsin B mRNA levels and proteolytic activity, inhibiting digestion. by Louise S. Goupil (2922159)

“…<b>C)</b> Fluorescence from digestion of Rh-BSA is decreased in worms treated with SmedCB dsRNA. …”

Data_Sheet_1_PTEN Expression Regulates Gap Junction Connectivity in the Retina.PDF by Ashley M. Chen (10828518)

“…The number of connexin36 puncta, the predominant connexin that mediates gap junction communication at electrical synapses, was decreased by at least 50% on OFF α-ganglion cells. …”

Metabolic and neuronal origins of the intrinsic flavoprotein signal response. by Cedric R. Uytingco (3371243)

“…<p><b>(A)</b> Mean flavoprotein signal amplitude of the light phase (black) and dark phase (gray) from the GL (solid) and EPL (dash) upon treatment with 10 μM DPI. …”

Data_Sheet_1_Where Might We Find Ecologically Intact Communities?.docx by Andrew J. Plumptre (8140635)

Toxicity assessment of cobalt ferrite nanoparticles on wheat plants by J. López–Luna (5390381)

“…Plant stress was indicated by a significant decrease in photosynthetic pigments. …”

Participant demographics and symptom severity. by Ravi Bansal (113103)

“…The excellent remission rate in duloxetine-treated patients is likely because of their treatment with a high dose (~95 mg/day) of duloxetine. <i>Responder</i> is defined as a patient whose symptom severity at week 10 decreased by 50% or more relative to its baseline severity. …”