Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways by Thomas S. Weiss (293554)

“…Endogenous sfALR but not rhALR treatment lowered TAG levels, diminished activation of ER-stress mediators C-Jun N-terminal kinase (JNK), X-box binding protein-1 (XBP1) and proapoptotic transcription factor C/EBP-homologous protein (CHOP), and reduced death receptor 5 protein expression. Cellular ALR exerts its lipid lowering and anti-apoptotic actions by enhancing FABP1, which binds toxic FFA, increasing mitochondrial β-oxidation by elevating the mitochondrial FFA transporter CPT1α, and decreasing ELOVL6, which delivers toxic FFA metabolites. …”

<i>Hbp1</i> expression in <i>Rb</i>^<i>+/+</i> and <i>Rb</i>^<i>-/-</i> mutant XY gonads. by Cassy M. Spiller (3687520)

“…<p>Using qRT-PCR analysis, normalizing gene expression to <i>18S</i>RNA, both <i>Fl-Hbp1</i> <b>(A)</b> and <i>ΔHbp1</i> <b>(B)</b> gene expression was significantly increased in <i>Rb</i>^<i>-/-</i> mutant XY gonads at 14.5 dpc. …”

The distribution of non-survivors based on the quartiles of absolute neutrophil and lymphocyte counts, and serum CRP and albumin levels in patients with polymyositis/dermatomyositi... by You-Jung Ha (2000266)

Table_1_A techno-economic model of mycoprotein production: achieving price parity with beef protein.XLSX by Derrick Risner (16624056)

“…<p>Predicted famines due to population increase created an interest in the development of protein alternatives during the 1950s. Currently, a renewed interest in protein alternatives has developed as a potential strategy to decrease the environmental impact of protein production and meet the global demand for protein as the population increases. …”

Resveratrol exhibits a dual effect on doublecortin-cells in female Balb/C mice at six months of age. by Mario Torres-Pérez (840055)

“…(<b>B)</b> Doublecortin (DCX)-labeled cells show significant decrease in mice treated with 1 and 5 mg/kg of RVTL (*<i>p</i> = 0.002, **<i>p</i> = 0.007, respectively). …”

GABA_AR activation during SD contributes to cellular Cl⁻ influx. by Isamu Aiba (488976)

“…<b>A</b>. Representative [Cl⁻]_o change during SD, characterized as an Initial decrease and a subsequent slow overshoot response. …”

Post-burn cardiac function <i>in vivo</i> and <i>ex vivo</i> in a Langendorff preparation. by Rong Xiao (130656)

“…</b> In isolated hearts perfused with a Langendorff apparatus, the recorded cardiac mechanical parameters LVSP and ± dp/dt max decreased from 1 h to 12 h post-burn, similar to the changes seen <i>in vivo</i>. …”

A working model of the signaling pathway involved on the IL-12p40 expression induced by PGN in BEC. by Ricarda Cortés-Vieyra (773900)

Stress increases both mature spines and colocalization of GluA2 with PSD-95 in area CA1. by Veronica Sebastian (476615)

“…<p>(A-D) Representative 2D reconstruction of dendrites for control (A, C) and stress (B, D) conditions (scale bar = 5mm for A-B; 3mm for C-D). …”

Scatter plots and approximate lines of changes in body composition and duration. by Kenji Yamaoka (11965273)

DataSheet1_Ambient Air Quality Standards and Policies in Eastern Mediterranean Countries: A Review.docx by Sasan Faridi (9277880)

“…We estimated that the reduction of annual mean PM_2.5 exposure level to the AQG level (5 μg m⁻³) would be associated with a decrease of all natural-cause mortality in adults (age 30+) by 16.9%–42.1% in various EMR countries. …”

Freeze-Casting Synthesis and Life Cycle Assessment of Closed-Loop Recyclable and High-Flux Polyvinylidene Fluoride Organogels by Yong Kong (224694)

“…A PVDF organogel with a 5 wt % PVDF content and a freezing temperature of −100 °C demonstrates a separation flux of 385 L m^–2 h^–1 and a half-life of 870 min for an oil–water emulsion. …”

Freeze-Casting Synthesis and Life Cycle Assessment of Closed-Loop Recyclable and High-Flux Polyvinylidene Fluoride Organogels by Yong Kong (224694)

“…A PVDF organogel with a 5 wt % PVDF content and a freezing temperature of −100 °C demonstrates a separation flux of 385 L m^–2 h^–1 and a half-life of 870 min for an oil–water emulsion. …”

Image_1_Corrected Serum Ionized Calcium as a Risk Factor Related to Adult Dyslipidemia.JPEG by Ke Yun (12325793)

“…High [Ca2+]corr levels were positively associated with elevated TC, LDL-C, and Non-HDL-C but inversely associated with decreased HDL-C odds. Moreover, Locally weighted regression (Loess) analyses showed a non-linear, positive relationship between [Ca2+]corr and TG, TC, HDL-C, LDL-C, and Non-HDL-C levels.…”

Examining MEmory Training for Recovery-Adolescent among Afghan adolescent boys: a pilot randomised controlled trial by Sayed Jafar Ahmadi (12377071)

“…Following the intent-to-treat principle, linear mixed effects models found at posttreatment the METRA group had a 20.89-point (95%CI −30.66, −11.11) decrease in PTSD symptoms, while the Control Group had a 1.42-point (95%CI −8.11, 5.27) decrease, with the group over time interaction being significant (<i>p </i>< .001). …”

Development of a multivariable prediction model for identification of patients at risk for medication transfer errors at ICU discharge by Liesbeth B. E. Bosma (6650735)

“…TC=4159" target="_blank">NTR4159</a>, 5 September 2013, retrospectively registered.…”

Image1_Identification of a chromatin regulator signature and potential prognostic ability for adrenocortical carcinoma.TIF by Junwu Li (13431636)

“…Furthermore, this work adopted the R package “pRRophetic” for exploring and estimating the sensitivity of patients to different chemotherapeutic agents.</p><p>Results: A 5-CR model was established to predict ACC survival, and the CR signature was confirmed as a factor in order to independently predict ACC patient prognosis. …”

Impact of a <em>Plasmodium falciparum</em> AMA1 Vaccine on Antibody Responses in Adult Malians by Alassane Dicko (22536)

“…AMA1 antibody responses to the 80 µg dose increased rapidly from baseline levels by days 14 and 28 after the first vaccination and continued to increase after the second vaccination. After a peak 14 days following the second vaccination, antibody levels decreased to baseline levels one year later at the time of the third vaccination that induced little or no increase in antibody levels.…”

Dynamine 3 as a diagnostic and prognostic biomarker in pancreatic cancer: Implications for early detection and targeted therapy by Fatih Yay (20606054)

“…<p>Dynamins are defined as a group of molecules with GTPase activity. Among them, DNM3 has gained recognition in oncology for its tumor suppressor role. …”

Image1_Eldecalcitol effectively prevents alveolar bone loss by partially improving Th17/Treg cell balance in diabetes-associated periodontitis.TIF by Ruihan Gao (8715957)

“…Western blotting and immunofluorescence staining showed increased p-STAT5 and decreased p-STAT3 levels after ELD application.…”