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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…(<b>C</b>) Isoginkgetin treatment leads to a decreased rate of lariat formation (* indicates <i>p</i> = 0.02) without affecting exon ligation or excised lariat degradation (<i>p</i> = 0.22, 0.08), with calculations as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089673#pone-0089673-g001" target="_blank">Fig. 1</a>. …”
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Resveratrol decreases PKM2 expression.
Published 2013“…<p>Resveratrol treatment decreases PKM2 mRNA in (A), HeLa; (B), HepG2 and (C), MCF-7; by approximately two-folds. β-actin was taken as endogenous control and normalized to PKM2 mRNA. …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Decreased macrophage recruitment correlates with decreased angiogenesis.
Published 2013“…<p>A) Quantification of BrdU incorporation demonstrates that decreased macrophage infiltration does not significantly correlate with a change in epithelial cell proliferation (N.S. = not significant). …”
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GFRα2 expression was dramatically decreased in Runx1 knockout mice.
Published 2013“…<p>ISH for GFRα2 in WT (<b><i>A</i></b>) and Runx1 knock out (<b><i>A<sup>/</sup></i></b>) mouse DRG showed significant reduction of GFRα2 in Runx1<sup>−/−</sup> ganglia. …”
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The ATR IR signal decreases with decreasing dilutions of cells.
Published 2013“…<p>Shown is a box plot for serial dilutions of a glioblastoma cell suspension. …”
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Decrease in proliferation after ENU-exposure as decrease in BrdU immunostaining.
Published 2013“…<p>Micrograph of the BrdU+ cells immunolabeled with DAB showed a decrease in the proliferation in the SVZ (B) and DG (D) of treated animals, compared with control group (A and C, respectively). …”
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Top Genes with Significantly Decreased Transcript Levels at the Site of SSTI<sup>1</sup>.
Published 2015“…<p><sup>1</sup>Top 50 genes with greatest negative change in LFC when comparing infected ears to uninfected ears from challenged mice for each time point represented</p><p><sup>2</sup>Function determined via Entrez (<a href="http://www.ncbi.nlm.nih.gov/" target="_blank">www.ncbi.nlm.nih.gov</a>) or Uniprot (<a href="http://www.uniprot.org/" target="_blank">www.uniprot.org</a>)</p><p><sup>3</sup>LFC = Log Fold Change</p><p>Italicized values indicate transcripts are significantly increased at the indicated time point.…”
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